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SSA1 [cytosol]
Stable Identifier
R-SCE-3371408-2
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
HSPA2, P10591
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Cellular response to heat stress (Saccharomyces cerevisiae)
Regulation of HSF1-mediated heat shock response (Saccharomyces cerevisiae)
HSP110s exchange ATP for ADP on HSP70s:ADP (Saccharomyces cerevisiae)
HSP70s:ADP [cytosol] (Saccharomyces cerevisiae)
HSPA2:ADP [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
HSP70s:ATP [cytosol] (Saccharomyces cerevisiae)
HSPA2:ATP [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Saccharomyces cerevisiae)
HSP70s:ADP [cytosol] (Saccharomyces cerevisiae)
HSPA2:ADP [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
HSP70s:ATP [cytosol] (Saccharomyces cerevisiae)
HSPA2:ATP [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
Hikeshi binds HSP70s:ATP (Saccharomyces cerevisiae)
HSP70s:ATP [cytosol] (Saccharomyces cerevisiae)
HSPA2:ATP [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
Hikeshi:HSP70s:ATP [cytosol] (Saccharomyces cerevisiae)
HSP70s:ATP [cytosol] (Saccharomyces cerevisiae)
HSPA2:ATP [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Saccharomyces cerevisiae)
Hikeshi:HSP70s:ATP [cytosol] (Saccharomyces cerevisiae)
HSP70s:ATP [cytosol] (Saccharomyces cerevisiae)
HSPA2:ATP [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Saccharomyces cerevisiae)
ATP binding to HSP90 triggers conformation change (Saccharomyces cerevisiae)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70:ADP [cytosol] (Saccharomyces cerevisiae)
HSP70 proteins [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
HSP90:STIP1:HSP70:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70:ADP:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70:ADP [cytosol] (Saccharomyces cerevisiae)
HSP70 proteins [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
ATP hydrolysis by HSP70 (Saccharomyces cerevisiae)
HSP40:HSP70:ADP:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70 proteins [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
HSP40:HSP70:ATP:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70 proteins [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
HSP70 proteins [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
HSP70 binds to HSP40:nascent protein (Saccharomyces cerevisiae)
HSP40:HSP70:ATP:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70 proteins [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
HSP70:ATP [cytosol] (Saccharomyces cerevisiae)
HSP70 proteins [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Saccharomyces cerevisiae)
HSP40:HSP70:ADP:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70 proteins [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
HSP90:STIP1:HSP70:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70:ADP:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70:ADP [cytosol] (Saccharomyces cerevisiae)
HSP70 proteins [cytosol] (Saccharomyces cerevisiae)
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
SSA1 [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P10591
Gene Names
SSA1
Reference Genes
BioGPS Gene:851259 SSA1
ENSEMBL:YAL005C
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YAL005C SSA1
Monarch:851259 SSA1
NCBI Gene:851259 SSA1
SGD:YAL005C
Reference Transcript
RefSeq:NM_001178151.1 SSA1
Other Identifiers
11315_i_at
11316_r_at
11317_s_at
1771860_at
851259
GO:0000049
GO:0000060
GO:0000166
GO:0000209
GO:0000329
GO:0002181
GO:0003674
GO:0003723
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005618
GO:0005634
GO:0005737
GO:0005773
GO:0005829
GO:0005844
GO:0005886
GO:0006457
GO:0006605
GO:0006606
GO:0006616
GO:0006626
GO:0007005
GO:0008150
GO:0009277
GO:0015031
GO:0016020
GO:0016787
GO:0016887
GO:0017053
GO:0031072
GO:0035617
GO:0042026
GO:0043161
GO:0043167
GO:0044183
GO:0045892
GO:0051082
GO:0051085
GO:0051169
GO:0051603
GO:0055085
GO:0070482
GO:0070647
GO:0072318
GO:0072671
GO:0090344
GO:0140657
GO:0140662
Participates
as a member of
Homologues of HSPA2 [cytosol] (Saccharomyces cerevisiae)
Other forms of this molecule
SSA1 [cytosol]
SSA1 [cytosol]
SSA1 [ficolin-1-rich granule lumen]
SSA1 [ficolin-1-rich granule lumen]
SSA1 [extracellular region]
SSA1 [extracellular region]
SSA1 [secretory granule lumen]
SSA1 [nucleoplasm]
SSA1 [nucleoplasm]
SSA1 [nucleoplasm]
SSA1 [nucleoplasm]
SSA1 [nucleoplasm]
SSA1 [nucleoplasm]
SSA1 [cytosol]
SSA1 [cytosol]
SSA1 [cytosol]
Inferred From
HSPA2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_009396.2
PRO
P10591
PDB
5LYN
,
3LCA
,
5Z8I
,
5Z8Q
Interactors (40)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P32589
5
SSE1 [nucleoplasm]
(R-SCE-5252053)
SSE1 [nucleoplasm]
(R-SCE-5251998)
SSE1 [cytosol]
(R-SCE-5251943)
SSE1 [cytosol]
(R-SCE-5251946)
SSE1 [cytosol]
(R-SCE-3299412)
0.892
10
UniProt:Q12118 SGT2
2
SGT2 [cytosol]
(R-SCE-9629049)
SGT2 [cytosol]
(R-SCE-5423595)
0.744
4
UniProt:P02829
11
HSP90AB1 [secretory granule lumen]
(R-SCE-6801477)
HSP90AA1 [secretory granule lumen]
(R-SCE-6801515)
HSP90AB1 [extracellular region]
(R-SCE-6806463)
HSP90AA1 [ficolin-1-rich granule lumen]
(R-SCE-6801470)
HSP90AB1 [ficolin-1-rich granule lumen]
(R-SCE-6801491)
HSP90AA1 [plasma membrane]
(R-SCE-534996)
HSP90AA1 [extracellular region]
(R-SCE-3221946)
HSP90AB1 [cytosol]
(R-SCE-419617)
HSP90AA1 [nucleoplasm]
(R-SCE-5082401)
HSP90AB1 [nucleoplasm]
(R-SCE-5082399)
HSP90AA1 [cytosol]
(R-SCE-192864)
0.744
5
UniProt:Q01939
1
PSMC5 [cytosol]
(R-SCE-68780)
0.669
3
UniProt:Q08972
1
ABCF1 [cytosol]
(R-SCE-5216139)
0.643
3
UniProt:P38996
2
NAB3 [nucleoplasm]
(R-SCE-4570543)
NAB3 [nucleoplasm]
(R-SCE-71933)
0.643
3
UniProt:P29547
1
CAM1 [cytosol]
(R-SCE-156925)
0.643
3
UniProt:P14680
3
monoSUMO1-K32-HIPK2 [nucleoplasm]
(R-SCE-4090405)
HIPK2 [nucleoplasm]
(R-SCE-3215222)
HIPK1 [nucleoplasm]
(R-SCE-3215224)
0.643
3
UniProt:P40344
8
ATG3 [cytosol]
(R-SCE-5671860)
CysO264-ATG3-MAP1LC3A [cytosol]
(R-SCE-9819371)
CysO264-ATG3-GABARAP [cytosol]
(R-SCE-9819379)
CysO264-ATG3-GABARAPL2 [cytosol]
(R-SCE-9819376)
CysO264-ATG3-MAP1LC3C [cytosol]
(R-SCE-9819377)
CysO264-ATG3-GABARAPL1 [cytosol]
(R-SCE-9819381)
CysO264-ATG3-MAP1LC3B [cytosol]
(R-SCE-9819365)
CysO264-ATG3-GABARAPL3 [cytosol]
(R-SCE-5683569)
0.527
2
UniProt:Q08920
2
NCBP2 [cytosol]
(R-SCE-162458)
NCBP2 [nucleoplasm]
(R-SCE-51463)
0.527
2
UniProt:P53043
1
PPP5C [nucleoplasm]
(R-SCE-5683410)
0.527
2
UniProt:P32324 EFT1
11
Me3K525-EEF2 [cytosol]
(R-SCE-8932237)
diphthine EFT1 [cytosol]
(R-SCE-5367015)
Me-diphthine EFT1 [cytosol]
(R-SCE-5367013)
diphthine EEF2 [cytosol]
(R-SCE-5358501)
nascent EEF2 [cytosol]
(R-SCE-5358472)
Me-diphthine EEF2 [cytosol]
(R-SCE-5367025)
aminocarboxypropyl EEF2 [cytosol]
(R-SCE-5358478)
EEF2 [cytosol]
(R-SCE-156901)
EEF2 [secretory granule lumen]
(R-SCE-6801504)
EEF2 [ficolin-1-rich granule lumen]
(R-SCE-6801513)
EEF2 [extracellular region]
(R-SCE-6806499)
0.527
3
UniProt:P29055
1
GTF2B [nucleoplasm]
(R-SCE-65888)
0.527
2
UniProt:Q12447
1
PAA1 [cytosol]
(R-SCE-209813)
0.527
2
UniProt:P38431
1
EIF5 [cytosol]
(R-SCE-72616)
0.527
2
UniProt:P33298
1
PSMC4 [cytosol]
(R-SCE-68777)
0.527
2
UniProt:P39935
2
phospho-TIF4631 [cytosol]
(R-SCE-165762)
TIF4631 [cytosol]
(R-SCE-72584)
0.527
2
UniProt:P38972
1
PFAS [cytosol]
(R-SCE-62500)
0.527
2
UniProt:P15303
4
phospho-p-S738,T744 SEC23A [cytosol]
(R-SCE-5685740)
SEC23A [ER to Golgi transport vesicle membrane]
(R-SCE-204024)
SEC23A [cytosol]
(R-SCE-203972)
SEC23A [endoplasmic reticulum membrane]
(R-SCE-203976)
0.527
2
UniProt:Q12377
4
RPN6 [cytosol]
(R-SCE-68790)
RPN6 [ficolin-1-rich granule lumen]
(R-SCE-6800436)
RPN6 [extracellular region]
(R-SCE-6806441)
RPN6 [secretory granule lumen]
(R-SCE-6800943)
0.527
2
UniProt:P15705
1
STI1 [cytosol]
(R-SCE-443857)
0.527
2
UniProt:P32471
2
EFB1 [cytosol]
(R-SCE-156926)
EFB1 [cytosol]
(R-SCE-156914)
0.527
2
UniProt:P22147 XRN1
2
XRN1 [nucleoplasm]
(R-SCE-6791205)
XRN1_YEAST [cytosol]
(R-SCE-429980)
0.527
2
UniProt:P43558
1
YOD1 [cytosol]
(R-SCE-6781909)
0.527
3
UniProt:P33299
4
PSMC2 [cytosol]
(R-SCE-68771)
PSMC2 [ficolin-1-rich granule lumen]
(R-SCE-6800421)
PSMC2 [extracellular region]
(R-SCE-6806472)
PSMC2 [secretory granule lumen]
(R-SCE-6800994)
0.527
2
UniProt:P36070
1
RRN3 [nucleoplasm]
(R-SCE-73714)
0.527
2
UniProt:Q04958
1
PNPLA6 [endoplasmic reticulum membrane]
(R-SCE-1498821)
0.527
2
UniProt:P12695
4
LAT1 [mitochondrial matrix]
(R-SCE-6792585)
LAT1 [mitochondrial matrix]
(R-SCE-9861594)
LAT1 [mitochondrial matrix]
(R-SCE-9861664)
LAT1 [mitochondrial matrix]
(R-SCE-69969)
0.527
2
UniProt:P06786
4
monoSUMO1-K-TOP2B [nucleoplasm]
(R-SCE-4641297)
TOP2B [nucleoplasm]
(R-SCE-4641359)
monoSUMO1-K-TOP2A [nucleoplasm]
(R-SCE-4641367)
TOP2A [nucleoplasm]
(R-SCE-1362276)
0.527
2
UniProt:Q00955
5
phospho-Btn-p-S222-ACACB [mitochondrial outer membrane]
(R-SCE-8876892-2)
Btn-ACACA [cytosol]
(R-SCE-2976730)
ACACA [cytosol]
(R-SCE-1660609)
ACACB [mitochondrial outer membrane]
(R-SCE-4167505-2)
Btn-ACACB [mitochondrial outer membrane]
(R-SCE-2993858-2)
0.527
2
UniProt:P50101
4
UBP15 [cytosol]
(R-SCE-5696900)
UBP15 [nucleoplasm]
(R-SCE-3215039)
UBP15 [cytosol]
(R-SCE-8853511)
UBP15 [nucleoplasm]
(R-SCE-3215278)
0.527
2
UniProt:Q01477
2
UBP3 [nucleoplasm]
(R-SCE-3222218)
UBP3 [cytosol]
(R-SCE-6782974)
0.527
2
UniProt:Q08723
4
RPN8 [secretory granule lumen]
(R-SCE-6801008)
RPN8 [extracellular region]
(R-SCE-6806488)
RPN8 [ficolin-1-rich granule lumen]
(R-SCE-6800406)
RPN8 [cytosol]
(R-SCE-68806)
0.527
2
UniProt:P32598
1
PPP1CC [cytosol]
(R-SCE-163443)
0.527
2
UniProt:P10592
20
SSA2 [cytosol]
(R-SCE-264476)
SSA2 [nucleoplasm]
(R-SCE-5082380)
SSA2 [cytosol]
(R-SCE-3371410-3)
SSA2 [cytosol]
(R-SCE-3371408-3)
SSA2 [cytosol]
(R-SCE-6792602-3)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801512-3)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801496-3)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801494)
SSA2 [extracellular region]
(R-SCE-6805872-3)
SSA2 [extracellular region]
(R-SCE-6806500-3)
SSA2 [extracellular region]
(R-SCE-6805936)
SSA2 [secretory granule lumen]
(R-SCE-6801530)
SSA2 [secretory granule lumen]
(R-SCE-6801472-3)
SSA2 [nucleoplasm]
(R-SCE-6792605-3)
SSA2 [nucleoplasm]
(R-SCE-912480-3)
SSA2 [nucleoplasm]
(R-SCE-5082367-3)
SSA2 [nucleoplasm]
(R-SCE-5252082-3)
SSA2 [nucleoplasm]
(R-SCE-5252088-3)
SSA2 [nucleoplasm]
(R-SCE-5252009-3)
SSA2 [cytosol]
(R-SCE-5251948-3)
0.527
3
UniProt:P16603
11
NOS2 [peroxisomal matrix]
(R-SCE-9033124)
phospho-2xPalmC-MyrG-p-S1177,S1179-NOS3 [plasma membrane]
(R-SCE-9860783)
phospho-2xPalmC-MyrG-p-S633-NOS3 [plasma membrane]
(R-SCE-9861341)
phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane]
(R-SCE-202139)
MyrG-NOS3 [Golgi membrane]
(R-SCE-534995)
MyrG-NOS3 [cytosol]
(R-SCE-203687)
2xPalmC-MyrG-NOS3 [plasma membrane]
(R-SCE-534993)
2xPalmC-MyrG-NOS3 [Golgi membrane]
(R-SCE-203769)
NOS1 [cytosol]
(R-SCE-419293)
NOS2 [cytosol]
(R-SCE-202107)
NOS3 [cytosol]
(R-SCE-202114)
0.527
2
UniProt:P25694
7
VCP [cytosol]
(R-SCE-1181251)
VCP [azurophil granule lumen]
(R-SCE-6800438)
VCP [extracellular region]
(R-SCE-6806191)
VCP [ficolin-1-rich granule lumen]
(R-SCE-6800425)
VCP [secretory granule lumen]
(R-SCE-6801039)
VCP [nucleoplasm]
(R-SCE-5643745)
Me3K315-VCP [cytosol]
(R-SCE-8932209)
0.527
2
UniProt:Q01217
1
ARG5,6 [mitochondrial matrix]
(R-SCE-70528)
0.527
2
UniProt:P12385 SUP45
4
Erf-1 [cytosol]
(R-SCE-141665)
SUP45 [cytosol]
(R-SCE-6800157)
SUP45 [cytosol]
(R-SCE-9629948)
SUP45 [cytosol]
(R-SCE-54433)
0.527
2
UniProt:P25491
3
SOH-C149,C150-DNAJA1 [cytosol]
(R-SCE-9857072)
DNAJA4 [cytosol]
(R-SCE-3371578)
DNAJA2 [cytosol]
(R-SCE-3371555)
0.527
3
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