Reactome | NAS6 [cytosol]

NAS6 [cytosol]

Stable Identifier

R-SCE-3640824-3

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

TNKS2, P50086

Locations in the PathwayBrowser

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Signal Transduction (Saccharomyces cerevisiae)

- Intracellular signaling by second messengers (Saccharomyces cerevisiae)
  - PIP3 activates AKT signaling (Saccharomyces cerevisiae)
    - PTEN Regulation (Saccharomyces cerevisiae)
      - Regulation of PTEN stability and activity (Saccharomyces cerevisiae)
        
        TNKS and TNKS2 PARylate PTEN (Saccharomyces cerevisiae)
        
        TNKS1/2 [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of TNKS2 [cytosol] (Saccharomyces cerevisiae)
        
        NAS6 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P50086

Gene Names

NAS6

Reference Genes

BioGPS Gene:853147 NAS6

ENSEMBL:YGR232W

KEGG:sce:YGR232W NAS6

Monarch:853147 NAS6

NCBI Gene:853147 NAS6

SGD:YGR232W

UCSC:P50086 NAS6

Reference Transcript

RefSeq:NM_001181361.3 NAS6

Other Identifiers

853147

GO:0003674

GO:0005515

GO:0005634

GO:0005829

GO:0006457

GO:0044183

GO:0070682

GO:1904855

Participates

as a member of

Homologues of TNKS2 [cytosol] (Saccharomyces cerevisiae)

Inferred From

TNKS2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_011748.3

ENSEMBL

YGR232W_mRNA, YGR232W, YGR232W

PRO

P50086

PDB

2DZO, 1IXV, 2DZN, 1WG0

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P33298	1	RPT3 [cytosol] (R-SCE-68777)	0.947	13
UniProt:P33299	4	RPT1 [cytosol] (R-SCE-68771) RPT1 [secretory granule lumen] (R-SCE-6800994) RPT1 [extracellular region] (R-SCE-6806472) RPT1 [ficolin-1-rich granule lumen] (R-SCE-6800421)	0.871	7
UniProt:Q04062	4	RPN9 [cytosol] (R-SCE-68794) RPN9 [secretory granule lumen] (R-SCE-6800983) RPN9 [extracellular region] (R-SCE-6806469) RPN9 [ficolin-1-rich granule lumen] (R-SCE-6800413)	0.784	7
UniProt:Q01939	2	RPT6 [cytosol] (R-SCE-68780) RPT6 [nucleoplasm] (R-SCE-174312)	0.784	8
UniProt:P33297	4	RPT5 [cytosol] (R-SCE-68774) RPT5 [secretory granule lumen] (R-SCE-6800917) RPT5 [extracellular region] (R-SCE-6806496) RPT5 [ficolin-1-rich granule lumen] (R-SCE-6800429)	0.784	5
UniProt:Q08723	4	RPN8 [cytosol] (R-SCE-68806) RPN8 [secretory granule lumen] (R-SCE-6801008) RPN8 [extracellular region] (R-SCE-6806488) RPN8 [ficolin-1-rich granule lumen] (R-SCE-6800406)	0.784	7
UniProt:P38886	1	RPN10 [cytosol] (R-SCE-68800)	0.773	5
UniProt:Q12250	4	RPN5 [cytosol] (R-SCE-68792) RPN5 [secretory granule lumen] (R-SCE-6800934) RPN5 [extracellular region] (R-SCE-6806480) RPN5 [ficolin-1-rich granule lumen] (R-SCE-6800416)	0.723	5
UniProt:Q12377	4	RPN6 [cytosol] (R-SCE-68790) RPN6 [secretory granule lumen] (R-SCE-6800943) RPN6 [extracellular region] (R-SCE-6806441) RPN6 [ficolin-1-rich granule lumen] (R-SCE-6800436)	0.723	6
UniProt:P32496	1	RPN12 [cytosol] (R-SCE-68808)	0.623	3
UniProt:P40327	1	RPT2 [cytosol] (R-SCE-68768)	0.623	3
UniProt:P53549	1	RPT4 [cytosol] (R-SCE-68783)	0.623	3
UniProt:P43593	1	UBP6 [cytosol] (R-SCE-5689541)	0.527	2
UniProt:P43588	4	RPN11 [cytosol] (R-SCE-68722) RPN11 [secretory granule lumen] (R-SCE-6800926) RPN11 [extracellular region] (R-SCE-6806511) RPN11 [ficolin-1-rich granule lumen] (R-SCE-6800419)	0.527	2

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