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SMT3 [nucleoplasm]
Stable Identifier
R-SCE-3730616
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
nucleoplasm
Synonyms
UBA2-G97-SUMO1, Q12306
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
SUMOylation (Saccharomyces cerevisiae)
Processing and activation of SUMO (Saccharomyces cerevisiae)
SUMO is conjugated to E1 (UBA2:SAE1) (Saccharomyces cerevisiae)
Conjugation of SUMO1 to UBA2:SAE1 (Saccharomyces cerevisiae)
SUMO1:UBA2:SAE1 [nucleoplasm] (Saccharomyces cerevisiae)
SUMO1:UBA2 [nucleoplasm] (Saccharomyces cerevisiae)
SMT3 [nucleoplasm] (Saccharomyces cerevisiae)
SUMO is transferred from E1 to E2 (UBE2I, UBC9) (Saccharomyces cerevisiae)
Transfer of SUMO1 from E1 to UBE2I (UBC9) (Saccharomyces cerevisiae)
SUMO1:UBA2:SAE1 [nucleoplasm] (Saccharomyces cerevisiae)
SUMO1:UBA2 [nucleoplasm] (Saccharomyces cerevisiae)
SMT3 [nucleoplasm] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:Q12306
Gene Names
SMT3
Reference Genes
BioGPS Gene:852122 SMT3
ENSEMBL:YDR510W
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YDR510W SMT3
Monarch:852122 SMT3
NCBI Gene:852122 SMT3
SGD:YDR510W
Reference Transcript
RefSeq:NM_001180818.1 SMT3
Other Identifiers
1776081_at
5979_at
852122
GO:0000794
GO:0003674
GO:0005515
GO:0005575
GO:0005634
GO:0005694
GO:0005737
GO:0005856
GO:0005938
GO:0005940
GO:0008150
GO:0016925
GO:0018193
GO:0019899
GO:0031386
GO:0042802
GO:0044389
GO:0070647
Participates
as a component of
SUMO1:UBA2 [nucleoplasm] (Saccharomyces cerevisiae)
Other forms of this molecule
SMT3 [cytosol]
SMT3 [nucleoplasm]
SMT3 [nucleoplasm]
SMT3 [nucleoplasm]
Inferred From
UBA2-G97-SUMO1 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
Inter-chain Crosslink via S-(glycyl)-L-cysteine (Cys-Gly) at 97 and 173 (in Homo sapiens)
Coordinate
97
PsiMod Name
S-(glycyl)-L-cysteine (Cys-Gly)
PsiMod Definition
A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.
Cross References
RefSeq
NP_010798.1
PRO
Q12306
PDB
1L2N
,
6UKX
,
6RPQ
,
6UKY
,
6O4A
,
5D6J
,
7P9P
,
3QHT
,
5JNE
,
4GGQ
,
5YC2
,
5V8T
,
6UKV
,
3TIX
,
6UKW
,
7ZHS
,
7P9L
,
6P81
,
3VAW
,
4G50
,
6UKM
,
4FN2
,
7SDE
,
8DMB
,
6Q2S
,
6UKZ
,
8UZH
,
6UL0
,
3PGE
,
5YCA
,
3UF8
,
1EUV
,
7ZWL
,
7O2W
,
6O49
,
7P7W
,
6CFP
,
6VW2
,
4GIV
,
3UQB
,
8B7F
,
6UKU
,
7P47
,
7PA1
,
3V62
,
7P7I
,
2EKE
,
3UQA
,
3V61
,
6VEL
,
5KLX
,
8R1G
,
7LTO
,
8R1F
,
3V60
,
7P9Y
Interactors (33)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P50623
5
UBC9 [nucleoplasm]
(R-SCE-4085358)
UBC9 [cytosol]
(R-SCE-4656944)
UBC9 [cytosol]
(R-SCE-4656909)
UBC9 [nucleoplasm]
(R-SCE-3730617)
UBC9 [nucleoplasm]
(R-SCE-912481)
0.757
4
UniProt:Q08204
1
SMC5 [nucleoplasm]
(R-SCE-2993751)
0.728
5
UniProt:P14291 RED1
0.704
9
UniProt:P12954 SRS2
0.704
4
UniProt:P15873
5
POL30 [nucleoplasm]
(R-SCE-4615861)
POL30 [nucleoplasm]
(R-SCE-8943000)
POL30 [nucleoplasm]
(R-SCE-5653768)
POL30 [nucleoplasm]
(R-SCE-5651986)
POL30 [nucleoplasm]
(R-SCE-68439)
0.698
6
UniProt:Q12050 ELG1
0.683
11
UniProt:Q12306
5
SMT3 [cytosol]
(R-SCE-4656941)
SMT3 [nucleoplasm]
(R-SCE-3730622)
SMT3 [nucleoplasm]
(R-SCE-3730616)
SMT3 [nucleoplasm]
(R-SCE-877304)
SMT3 [nucleoplasm]
(R-SCE-2990831)
0.681
3
UniProt:P06778
3
RAD52 [nucleoplasm]
(R-SCE-4568909)
RAD52 [nucleoplasm]
(R-SCE-62639)
phospho-RAD52 [nucleoplasm]
(R-SCE-5686588)
0.589
2
UniProt:P53044
2
UFD1 [nucleoplasm]
(R-SCE-5654993)
UFD1 [cytosol]
(R-SCE-9668519)
0.567
3
UniProt:P25694
7
VCP [cytosol]
(R-SCE-1181251)
VCP [azurophil granule lumen]
(R-SCE-6800438)
VCP [extracellular region]
(R-SCE-6806191)
VCP [ficolin-1-rich granule lumen]
(R-SCE-6800425)
VCP [secretory granule lumen]
(R-SCE-6801039)
VCP [nucleoplasm]
(R-SCE-5643745)
Me3K315-VCP [cytosol]
(R-SCE-8932209)
0.567
3
UniProt:P52488
2
SUMO1-C173-UBA2 [nucleoplasm]
(R-SCE-3730628)
UBA2 [nucleoplasm]
(R-SCE-947696)
0.558
2
UniProt:P63279 UBE2I
9
monoSUMO1-K14-UBE2I [nucleoplasm]
(R-HSA-4085358)
UBE2I [nuclear envelope]
(R-HSA-4655408)
SUMO2-C93-UBE2I [cytosol]
(R-HSA-4656944)
SUMO3-C93-UBE2I [nucleoplasm]
(R-HSA-3730629)
UBE2I [cytosol]
(R-HSA-4655342)
SUMO1-C93-UBE2I [cytosol]
(R-HSA-4656909)
SUMO2-C93-UBE2I [nucleoplasm]
(R-HSA-3730619)
SUMO1-C93-UBE2I [nucleoplasm]
(R-HSA-3730617)
UBE2I [nucleoplasm]
(R-HSA-912481)
0.556
3
UniProt:P23497-2 SP100
0.556
3
UniProt:Q9HCK0 ZBT26
0.556
3
UniProt:H3BQQ9 H3BQQ9
0.556
3
UniProt:Q03718 NSE5
0.553
2
UniProt:P38319 TYDP1
0.553
2
UniProt:Q04110 ECM11
0.553
2
UniProt:P32828 SLX5
0.553
2
UniProt:P35187
1
BLM [nucleoplasm]
(R-SCE-174881)
0.527
3
UniProt:P07271 PIF1
0.524
2
UniProt:P32797 CDC13
0.524
3
UniProt:Q04437
3
YKU80 [extracellular region]
(R-SCE-6806530)
YKU80 [secretory granule lumen]
(R-SCE-6801297)
YKU80 [nucleoplasm]
(R-SCE-58274)
0.524
2
UniProt:P30665 MCM4
2
yMcm4 [nucleoplasm]
(R-SCE-169496)
MCM4 [nucleoplasm]
(R-SCE-68549)
0.524
2
UniProt:P29496 MCM5
2
yMcm5 [nucleoplasm]
(R-SCE-169511)
MCM5 [nucleoplasm]
(R-SCE-68551)
0.524
3
UniProt:P32807
4
YKU70 [secretory granule lumen]
(R-SCE-6801312)
YKU70 [extracellular region]
(R-SCE-6806444)
YKU70 [ficolin-1-rich granule lumen]
(R-SCE-6801300)
YKU70 [nucleoplasm]
(R-SCE-58272)
0.524
2
UniProt:P29469 MCM2
2
MCM2 [nucleoplasm]
(R-SCE-68557)
yMcm2 [nucleoplasm]
(R-SCE-169497)
0.524
2
UniProt:P38132 MCM7
2
yMcm7 [nucleoplasm]
(R-SCE-169505)
MCM7 [nucleoplasm]
(R-SCE-68555)
0.524
2
UniProt:P53091 MCM6
2
yMcm6 [nucleoplasm]
(R-SCE-169504)
MCM6 [nucleoplasm]
(R-SCE-68553)
0.524
2
UniProt:P24279 MCM3
2
yMcm3 [nucleoplasm]
(R-SCE-169513)
MCM3 [nucleoplasm]
(R-SCE-68546)
0.524
2
UniProt:P31111
5
ZIP1 [cytosol]
(R-SCE-1449561-2)
ZIP1 [cytosol]
(R-SCE-419176-2)
ZIP1 [cytosol]
(R-SCE-419173-2)
ZIP1 [cytosol]
(R-SCE-420855-2)
ZIP1 [cytosol]
(R-SCE-419174-2)
0.502
2
UniProt:P32908
4
SMC1A [cytosol]
(R-SCE-2484798)
SMC1A [chromosome]
(R-SCE-1638774)
SMC1A [chromosome, centromeric region]
(R-SCE-2466015)
SMC1A [nucleoplasm]
(R-SCE-64561)
0.499
2
UniProt:P25454
2
RAD51 [nucleoplasm]
(R-SCE-62637)
phospho-p-T309-RAD51 [nucleoplasm]
(R-SCE-5685231)
0.482
2
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