Reactome | ASF1 [nucleoplasm]

ASF1 [nucleoplasm]

Stable Identifier

R-SCE-417169

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

ASF1A, P32447

Locations in the PathwayBrowser for interactor UniProt:P40513

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Cellular responses to stimuli (Saccharomyces cerevisiae)

- Cellular responses to stress (Saccharomyces cerevisiae)
  - Cellular Senescence (Saccharomyces cerevisiae)
    - DNA Damage/Telomere Stress Induced Senescence (Saccharomyces cerevisiae)
      - Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Saccharomyces cerevisiae)
        
        Initiation of SAHF formation (Saccharomyces cerevisiae)
        
        ASF1 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P32447

Gene Names

ASF1

Reference Genes

BioGPS Gene:853327 ASF1

ENSEMBL:YJL115W

KEGG:sce:YJL115W ASF1

Monarch:853327 ASF1

NCBI Gene:853327 ASF1

SGD:YJL115W

UCSC:P32447 ASF1

Reference Transcript

RefSeq:NM_001181548.1 ASF1

Other Identifiers

853327

GO:0000781

GO:0000785

GO:0000790

GO:0001207

GO:0001932

GO:0003674

GO:0005515

GO:0005575

GO:0005634

GO:0005829

GO:0006282

GO:0006325

GO:0006334

GO:0006335

GO:0006336

GO:0006337

GO:0006348

GO:0006357

GO:0008150

GO:0010468

GO:0010698

GO:0016573

GO:0030234

GO:0030466

GO:0031399

GO:0031509

GO:0032968

GO:0033523

GO:0033554

GO:0035066

GO:0036211

GO:0042393

GO:0043486

GO:0043618

GO:0051052

GO:0051726

GO:0070775

GO:2000002

Participates

as an input of

Initiation of SAHF formation (Saccharomyces cerevisiae)

as a component of

HIRA:ASF1A:UBN1:CABIN1 [nucleoplasm] (Saccharomyces cerevisiae)

Inferred From

ASF1A [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_012420.1

ENSEMBL

YJL115W, YJL115W_mRNA, YJL115W

PRO

P32447

PDB

5UEK, 1WG3, 6AYZ, 1ROC, 5EII, 2IDC, 6F0Y, 5UEA, 4EO5, 2HUE, 5UCB, 2YGV, 4ZBJ, 6O22, 7UNK, 6AZ2

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P22216 RAD53			0.905	33
UniProt:P47171	1	HIR3 [nucleoplasm] (R-SCE-3878125)	0.814	12
UniProt:P02309	14	HHF1; HHF2 [nucleoplasm] (R-SCE-181902) HHF1; HHF2 [nucleoplasm] (R-SCE-5651652) HHF1; HHF2 [nucleoplasm] (R-SCE-5423110) HHF1; HHF2 [nucleoplasm] (R-SCE-3451124) HHF1; HHF2 [nucleoplasm] (R-SCE-4568758) HHF1; HHF2 [nucleoplasm] (R-SCE-4568748) HHF1; HHF2 [nucleoplasm] (R-SCE-427469) HHF1; HHF2 [nucleoplasm] (R-SCE-5651656) HHF1; HHF2 [nucleoplasm] (R-SCE-4754240) HHF1; HHF2 [nucleoplasm] (R-SCE-4754243) HHF1; HHF2 [nucleoplasm] (R-SCE-5229015) HHF1; HHF2 [nucleoplasm] (R-SCE-4568744) HHF1; HHF2 [nucleoplasm] (R-SCE-212078) HHF1; HHF2 [nucleoplasm] (R-SCE-4570518)	0.809	20
UniProt:P32479	1	HIR1 [nucleoplasm] (R-SCE-2532790)	0.797	17
UniProt:P61830	13	HHT1; HHT2 [nucleoplasm] (R-SCE-1214206) HHT1; HHT2 [nucleoplasm] (R-SCE-212295) HHT1; HHT2 [nucleoplasm] (R-SCE-212282) HHT1; HHT2 [nucleoplasm] (R-SCE-5250654) phospho-HHT1; HHT2 [nucleoplasm] (R-SCE-5625878) phospho-HHT1; HHT2 [nucleoplasm] (R-SCE-5625858) HHT1; HHT2 [nucleoplasm] (R-SCE-5625800) phospho-HHT1; HHT2 [nucleoplasm] (R-SCE-5625758) HHT1; HHT2 [nucleoplasm] (R-SCE-5625747) HHT1; HHT2 [nucleoplasm] (R-SCE-427324) HHT1; HHT2 [nucleoplasm] (R-SCE-1214216) HHT1; HHT2 [nucleoplasm] (R-SCE-427504) HHT1; HHT2 [nucleoplasm] (R-SCE-427369)	0.752	36
UniProt:Q04003 SAS4			0.721	5
UniProt:Q01448	1	HPC2 [nucleoplasm] (R-SCE-2532791)	0.69	11
UniProt:P32480 HIR2			0.69	17
UniProt:P40963 SAS2			0.632	4
UniProt:P84233 Unknown	2	Histone H3.2 [nucleoplasm] (R-XLA-4549227) Ack15-histone H3.2 [nucleoplasm] (R-XLA-4549248)	0.59	3
UniProt:P62799 H4			0.59	3
UniProt:P15790 CKA1	5	CKA1 [nucleoplasm] (R-SCE-6790643) CKA1 [nucleoplasm] (R-SCE-6805057) CKA1 [nucleoplasm] (R-SCE-6805065) CKA1 [cytosol] (R-SCE-201721) CKA1 [cytosol] (R-SCE-201713)	0.564	8
UniProt:P19454 CKA2	5	CKA2 [nucleoplasm] (R-SCE-6790631) CKA2 [nucleoplasm] (R-SCE-6805057-2) CKA2 [nucleoplasm] (R-SCE-6805065-2) CKA2 [cytosol] (R-SCE-201721-2) CKA2 [cytosol] (R-SCE-201713-2)	0.564	5
UniProt:Q99314 SAS5			0.547	2
UniProt:P10592	20	SSA2 [cytosol] (R-SCE-264476) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801496-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494) SSA2 [extracellular region] (R-SCE-6805872-3) SSA2 [extracellular region] (R-SCE-6806500-3) SSA2 [extracellular region] (R-SCE-6805936) SSA2 [secretory granule lumen] (R-SCE-6801530) SSA2 [secretory granule lumen] (R-SCE-6801472-3) SSA2 [cytosol] (R-SCE-3371410-3) SSA2 [cytosol] (R-SCE-3371408-3) SSA2 [cytosol] (R-SCE-6792602-3) SSA2 [nucleoplasm] (R-SCE-5082380) SSA2 [nucleoplasm] (R-SCE-6792605-3) SSA2 [nucleoplasm] (R-SCE-912480-3) SSA2 [nucleoplasm] (R-SCE-5082367-3) SSA2 [nucleoplasm] (R-SCE-5252082-3) SSA2 [nucleoplasm] (R-SCE-5252088-3) SSA2 [nucleoplasm] (R-SCE-5252009-3) SSA2 [cytosol] (R-SCE-5251948-3)	0.527	2
UniProt:P49723	1	RNR4 [cytosol] (R-SCE-111792-2)	0.527	2
UniProt:P09938	2	RNR2 [cytosol] (R-SCE-73639) RNR2 [cytosol] (R-SCE-111792)	0.527	2
UniProt:P11484	17	SSB1 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) SSB1 [ficolin-1-rich granule lumen] (R-SCE-6801496-4) SSB1 [extracellular region] (R-SCE-6805872-4) SSB1 [extracellular region] (R-SCE-6806500-4) SSB1 [secretory granule lumen] (R-SCE-6801472-4) SSB1 [cytosol] (R-SCE-3371410-4) SSB1 [cytosol] (R-SCE-3371408-4) SSB1 [cytosol] (R-SCE-6792602-4) SSB1 [nucleoplasm] (R-SCE-6792605-4) SSB1 [nucleoplasm] (R-SCE-912480-4) SSB1 [nucleoplasm] (R-SCE-5082367-4) SSB1 [nucleoplasm] (R-SCE-5252082-4) SSB1 [nucleoplasm] (R-SCE-5252088-4) SSB1 [nucleoplasm] (R-SCE-5252009-4) SSB1 [cytosol] (R-SCE-5251948-4) SSB1 [cytosol] (R-SCE-5251981-4) SSB1 [cytosol] (R-SCE-3371521-4)	0.527	3
UniProt:P40513	1	MAM33 [cytosol] (R-SCE-9645690)	0.527	2
UniProt:P40161 RT106			0.499	5

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