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ATG8 [cytosol]
Stable Identifier
R-SCE-5205676
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
MAP1LC3A, P38182
Locations in the PathwayBrowser
Expand all
Autophagy (Saccharomyces cerevisiae)
Macroautophagy (Saccharomyces cerevisiae)
ATG16L1 complex transfers LC3 from ATG3 to PE (Saccharomyces cerevisiae)
LC3:PE [phagophore assembly site membrane] (Saccharomyces cerevisiae)
ATG8 [cytosol] (Saccharomyces cerevisiae)
Autophagosome maturation (Saccharomyces cerevisiae)
LC3:PE [phagophore assembly site membrane] (Saccharomyces cerevisiae)
ATG8 [cytosol] (Saccharomyces cerevisiae)
LC3 binds ATG7 dimer (Saccharomyces cerevisiae)
ATG8 [cytosol] (Saccharomyces cerevisiae)
Selective autophagy (Saccharomyces cerevisiae)
Mitophagy (Saccharomyces cerevisiae)
Receptor Mediated Mitophagy (Saccharomyces cerevisiae)
LC3 binds the autophagosome membrane Atg5-Atg12 complex (Saccharomyces cerevisiae)
p-S17-FUNDC1:LC3 [mitochondrial outer membrane] (Saccharomyces cerevisiae)
ATG8 [cytosol] (Saccharomyces cerevisiae)
p-S17-FUNDC1:LC3:ATG5:ATG12 [cytosol] (Saccharomyces cerevisiae)
p-S17-FUNDC1:LC3 [mitochondrial outer membrane] (Saccharomyces cerevisiae)
ATG8 [cytosol] (Saccharomyces cerevisiae)
Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Saccharomyces cerevisiae)
ATG8 [cytosol] (Saccharomyces cerevisiae)
p-S17-FUNDC1:LC3 [mitochondrial outer membrane] (Saccharomyces cerevisiae)
ATG8 [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P38182
Gene Names
ATG8
Reference Genes
BioGPS Gene:852200 ATG8
ENSEMBL:YBL078C
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YBL078C ATG8
Monarch:852200 ATG8
NCBI Gene:852200 ATG8
SGD:YBL078C
Reference Transcript
RefSeq:NM_001178318.1 ATG8
Other Identifiers
1772778_at
7464_at
852200
GO:0000045
GO:0000329
GO:0000407
GO:0000421
GO:0000422
GO:0003674
GO:0005515
GO:0005575
GO:0005737
GO:0005739
GO:0005740
GO:0005773
GO:0005774
GO:0005776
GO:0005829
GO:0006605
GO:0006888
GO:0006914
GO:0006995
GO:0007005
GO:0007033
GO:0008150
GO:0008289
GO:0008429
GO:0010324
GO:0015031
GO:0016020
GO:0016236
GO:0016241
GO:0019898
GO:0031386
GO:0031410
GO:0031503
GO:0031966
GO:0032258
GO:0033110
GO:0034497
GO:0034629
GO:0034727
GO:0042594
GO:0044804
GO:0044805
GO:0048193
GO:0061025
GO:0061709
GO:0070925
GO:0071211
GO:0120095
GO:1905153
Participates
as an input of
LC3 binds ATG7 dimer (Saccharomyces cerevisiae)
Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Saccharomyces cerevisiae)
as a component of
LC3:PE [phagophore assembly site membrane] (Saccharomyces cerevisiae)
p-S17-FUNDC1:LC3 [mitochondrial outer membrane] (Saccharomyces cerevisiae)
Other forms of this molecule
ATG8 [cytosol]
ATG8 [cytosol]
ATG8 [cytosol]
ATG8 [cytosol]
ATG8 [cytosol]
ATG8 [cytosol]
ATG8 [cytosol]
ATG8 [autophagosome membrane]
ATG8 [autophagosome membrane]
ATG8 [autophagosome membrane]
ATG8 [autophagosome membrane]
Inferred From
LC3 family [cytosol]
(Homo sapiens)
LC3 [cytosol]
(Homo sapiens)
MAP1LC3A [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_009475.1
PRO
P38182
PDB
7BRN
,
2KWC
,
2ZPN
,
3VXW
,
2KQ7
,
3RUI
,
6AAG
,
5YEC
,
3VH3
,
2LI5
,
6WY6
,
3VH4
Interactors (18)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P38862
12
ATG7 [cytosol]
(R-SCE-947867)
ATG7 [cytosol]
(R-SCE-5683584)
ATG7 [cytosol]
(R-SCE-9820420)
ATG7 [cytosol]
(R-SCE-9820421)
ATG7 [cytosol]
(R-SCE-9820407)
ATG7 [cytosol]
(R-SCE-9820406)
ATG7 [cytosol]
(R-SCE-9820417)
ATG7 [cytosol]
(R-SCE-9820413)
ATG7 [cytosol]
(R-SCE-9820410)
ATG7 [ficolin-1-rich granule lumen]
(R-SCE-6801293)
ATG7 [extracellular region]
(R-SCE-6806451)
ATG7 [secretory granule lumen]
(R-SCE-6801316)
0.942
12
UniProt:P40344
8
ATG3 [cytosol]
(R-SCE-5671860)
CysO264-ATG3-MAP1LC3A [cytosol]
(R-SCE-9819371)
CysO264-ATG3-GABARAP [cytosol]
(R-SCE-9819379)
CysO264-ATG3-GABARAPL2 [cytosol]
(R-SCE-9819376)
CysO264-ATG3-MAP1LC3C [cytosol]
(R-SCE-9819377)
CysO264-ATG3-GABARAPL1 [cytosol]
(R-SCE-9819381)
CysO264-ATG3-MAP1LC3B [cytosol]
(R-SCE-9819365)
CysO264-ATG3-GABARAPL3 [cytosol]
(R-SCE-5683569)
0.924
10
UniProt:Q12292 ATG34
0.743
4
UniProt:O60238 BNIP3L
1
BNIP3L [mitochondrial outer membrane]
(R-HSA-6798001)
0.666
4
UniProt:P35193 ATG19
0.65
5
UniProt:Q14596 NBR1
2
NBR1 [peroxisomal membrane]
(R-HSA-9665177)
NBR1 [cytosol]
(R-HSA-9665180)
0.635
7
UniProt:P53867 ATG4
0.635
3
UniProt:Q08412
3
CUE5 [specific granule lumen]
(R-SCE-6799719)
CUE5 [extracellular region]
(R-SCE-6800448)
CUE5 [azurophil granule lumen]
(R-SCE-6799709)
0.591
4
UniProt:Q12983 BNIP3
0.556
3
UniProt:Q92609 TBCD5
0.556
3
UniProt:O43379 WDR62
0.556
3
UniProt:Q96GX9 APIP
1
APIP [cytosol]
(R-HSA-1237171)
0.556
3
UniProt:Q9UH92-3 MLX
0.556
3
UniProt:P53104
7
ULK1 [recycling endosome]
(R-SCE-8854761)
phospho-p-S758-ULK1 [cytosol]
(R-SCE-5672131)
phospho-p-S317,467,556,638,T575-ULK1 [cytosol]
(R-SCE-5673747)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol]
(R-SCE-5675858)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [endoplasmic reticulum membrane]
(R-SCE-8948047)
ULK1 [mitochondrial outer membrane]
(R-SCE-8948145)
ULK1 [cytosol]
(R-SCE-1632847)
0.544
3
UniProt:Q99325 ATG40
0.508
3
UniProt:Q06159 ATG39
0.508
3
UniProt:Q13501 SQSTM1
7
SQSTM1(2-251)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9711967)
SQSTM1(2-251)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9711954)
K7 ub-SQSTM1 [cytosol]
(R-HSA-9759088)
p-S349 SQSTM1 [cytosol]
(R-HSA-9766524)
ub K420 p-S349 SQSTM1 [cytosol]
(R-HSA-9766536)
SQSTM1 [nucleoplasm]
(R-HSA-210961)
SQSTM1 [cytosol]
(R-HSA-193937)
0.508
3
UniProt:P22804
4
BET1 [Golgi membrane]
(R-SCE-6807744)
BET1 [Golgi membrane]
(R-SCE-6807743)
BET1 [transport vesicle]
(R-SCE-6808719)
BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-SCE-5688142)
0.499
2
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