Diphthamide biosynthesis protein 7 hydrolyzes a methyl group on Me-diphthine elongation factor 2

Stable Identifier
R-SCE-5367021
Type
Reaction [transition]
Species
Saccharomyces cerevisiae
Compartment
General
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Diphthamide biosynthesis protein 7 hydrolyzes a methyl group on Me-diphthine elongation factor 2

Yeast cytosolic diphthamide biosynthesis protein 7 (RRT2) catalyzes the removal of a methyl group of Me-diphthine elongation factor 2 (EFT1), yielding diphthine EFT1 (Lin et al. 2014).

Literature References
PubMed ID Title Journal Year
24739148 Dph7 catalyzes a previously unknown demethylation step in diphthamide biosynthesis

Chen, W, Ci, B, Zhang, S, Su, X, Lin, Z, Lin, H

J. Am. Chem. Soc. 2014
Participants
Catalyst Activity

protein methylesterase activity of Diphthamide biosynthesis protein 7 [cytosol]

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