Reactome | SEC16 [cytosol]

SEC16 [cytosol]

Stable Identifier

R-SCE-5685731

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

SEC16B, P48415

Locations in the PathwayBrowser

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Metabolism of proteins (Saccharomyces cerevisiae)

- Post-translational protein modification (Saccharomyces cerevisiae)
  - Asparagine N-linked glycosylation (Saccharomyces cerevisiae)
    - Transport to the Golgi and subsequent modification (Saccharomyces cerevisiae)
      - ER to Golgi Anterograde Transport (Saccharomyces cerevisiae)
        
        COPII-mediated vesicle transport (Saccharomyces cerevisiae)
        
        SEC31:SEC13 and v-SNARE recruitment (Saccharomyces cerevisiae)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
        
        SEC16A:SEC16B [cytosol] (Saccharomyces cerevisiae)
        
        SEC16 [cytosol] (Saccharomyces cerevisiae)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
        
        SEC16A:SEC16B [cytosol] (Saccharomyces cerevisiae)
        
        SEC16 [cytosol] (Saccharomyces cerevisiae)

Vesicle-mediated transport (Saccharomyces cerevisiae)

- Membrane Trafficking (Saccharomyces cerevisiae)
  - ER to Golgi Anterograde Transport (Saccharomyces cerevisiae)
    - COPII-mediated vesicle transport (Saccharomyces cerevisiae)
      - SEC31:SEC13 and v-SNARE recruitment (Saccharomyces cerevisiae)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
        
        SEC16A:SEC16B [cytosol] (Saccharomyces cerevisiae)
        
        SEC16 [cytosol] (Saccharomyces cerevisiae)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
        
        SEC16A:SEC16B [cytosol] (Saccharomyces cerevisiae)
        
        SEC16 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P48415

Gene Names

SEC16

Reference Genes

BioGPS Gene:856020 SEC16

ENSEMBL:YPL085W

KEGG:sce:YPL085W SEC16

Monarch:856020 SEC16

NCBI Gene:856020 SEC16

SGD:YPL085W

UCSC:P48415 SEC16

Reference Transcript

RefSeq:NM_001183899.1 SEC16

Other Identifiers

1779952_at

2532_g_at

2533_s_at

2534_s_at

2535_s_at

2536_s_at

2537_s_at

2538_s_at

7850_at

856020

GO:0000139

GO:0003674

GO:0005515

GO:0005575

GO:0005737

GO:0005783

GO:0005789

GO:0005794

GO:0006914

GO:0007030

GO:0008150

GO:0012505

GO:0012507

GO:0015031

GO:0016020

GO:0016050

GO:0016192

GO:0016236

GO:0030674

GO:0031410

GO:0043495

GO:0046907

GO:0048193

GO:0048208

GO:0070971

GO:0070973

Participates

as a component of

SEC16A:SEC16B [cytosol] (Saccharomyces cerevisiae)

Other forms of this molecule

SEC16 [cytosol]

Inferred From

SEC16B [cytosol] (Homo sapiens)

Cross References

ENSEMBL

YPL085W_mRNA

PRO

P48415

PDB

3MZK

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P15303	4	phospho-p-S738,T744 SEC23A [cytosol] (R-SCE-5685740) SEC23A [ER to Golgi transport vesicle membrane] (R-SCE-204024) SEC23A [cytosol] (R-SCE-203972) SEC23A [endoplasmic reticulum membrane] (R-SCE-203976)	0.716	6
UniProt:P10592	20	SSA2 [cytosol] (R-SCE-264476) SSA2 [nucleoplasm] (R-SCE-5082380) SSA2 [cytosol] (R-SCE-3371410-3) SSA2 [cytosol] (R-SCE-3371408-3) SSA2 [cytosol] (R-SCE-6792602-3) SSA2 [secretory granule lumen] (R-SCE-6801530) SSA2 [secretory granule lumen] (R-SCE-6801472-3) SSA2 [extracellular region] (R-SCE-6806500-3) SSA2 [extracellular region] (R-SCE-6805936) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801496-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494) SSA2 [extracellular region] (R-SCE-6805872-3) SSA2 [nucleoplasm] (R-SCE-6792605-3) SSA2 [nucleoplasm] (R-SCE-912480-3) SSA2 [nucleoplasm] (R-SCE-5082367-3) SSA2 [nucleoplasm] (R-SCE-5252082-3) SSA2 [nucleoplasm] (R-SCE-5252088-3) SSA2 [nucleoplasm] (R-SCE-5252009-3) SSA2 [cytosol] (R-SCE-5251948-3)	0.527	3
UniProt:P02309	14	HHF2 [nucleoplasm] (R-SCE-181902) HHF2 [nucleoplasm] (R-SCE-5651652) HHF2 [nucleoplasm] (R-SCE-5423110) HHF2 [nucleoplasm] (R-SCE-3451124) HHF2 [nucleoplasm] (R-SCE-4568758) HHF2 [nucleoplasm] (R-SCE-4568748) HHF2 [nucleoplasm] (R-SCE-427469) HHF2 [nucleoplasm] (R-SCE-5651656) HHF2 [nucleoplasm] (R-SCE-4754240) HHF2 [nucleoplasm] (R-SCE-4754243) HHF2 [nucleoplasm] (R-SCE-5229015) HHF2 [nucleoplasm] (R-SCE-4568744) HHF2 [nucleoplasm] (R-SCE-212078) HHF2 [nucleoplasm] (R-SCE-4570518)	0.527	2