Reactome | SED5 [endoplasmic reticulum-Golgi intermediate compartment membrane]

SED5 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-SCE-5688157

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

STX5, Q01590

Locations in the PathwayBrowser

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Metabolism of proteins (Saccharomyces cerevisiae)

- Post-translational protein modification (Saccharomyces cerevisiae)
  - Asparagine N-linked glycosylation (Saccharomyces cerevisiae)
    - Transport to the Golgi and subsequent modification (Saccharomyces cerevisiae)
      - ER to Golgi Anterograde Transport (Saccharomyces cerevisiae)
        
        COPII-mediated vesicle transport (Saccharomyces cerevisiae)
        
        NSF ATPase activity dissociates cis-SNARE (Saccharomyces cerevisiae)
        
        STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        SED5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        cis-SNARE:NSF hexamer:3xSNAP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        SED5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        NSF and SNAPs bind cis-SNARE complex (Saccharomyces cerevisiae)
        
        cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        SED5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        cis-SNARE:NSF hexamer:3xSNAP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        SED5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:Q01590

Gene Names

SED5

Reference Genes

BioGPS Gene:850713 SED5

ENSEMBL:YLR026C

KEGG:sce:YLR026C SED5

Monarch:850713 SED5

NCBI Gene:850713 SED5

SGD:YLR026C

UCSC:Q01590 SED5

Reference Transcript

RefSeq:NM_001181913.1 SED5

Other Identifiers

850713

GO:0000139

GO:0000149

GO:0003674

GO:0005484

GO:0005515

GO:0005575

GO:0005789

GO:0005794

GO:0005801

GO:0006886

GO:0006888

GO:0006891

GO:0006906

GO:0008150

GO:0012505

GO:0015031

GO:0016020

GO:0016021

GO:0016050

GO:0016192

GO:0030674

GO:0031201

GO:0048193

GO:0048278

GO:0048280

GO:0048284

GO:0061025

GO:0090083

GO:1990674

Participates

as a member of

STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)

Other forms of this molecule

SED5 [cytosol]

SED5 [Golgi membrane]

SED5 [ER to Golgi transport vesicle membrane]

SED5 [endoplasmic reticulum membrane]

Inferred From

STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Cross References

RefSeq

NP_013126.1

ENSEMBL

YLR026C, YLR026C, YLR026C_mRNA

PRO

Q01590

PDB

1PD0, 1MQS

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P22213	1	SLY1 [cytosol] (R-SCE-5688147)	0.853	8
UniProt:P22214	5	SEC22 [Golgi membrane] (R-SCE-6810993) SEC22 [transport vesicle] (R-SCE-6810994) SEC22 [ER to Golgi transport vesicle membrane] (R-SCE-5688565) SEC22 [endoplasmic reticulum membrane] (R-SCE-5688150) SEC22 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-SCE-5688566)	0.845	13
UniProt:P38736	1	GOS1 [Golgi membrane] (R-SCE-6807753)	0.8	6
UniProt:P01123	20	phospho-YPT1 [Golgi membrane] (R-SCE-2422374) phospho-YPT1 [Golgi membrane] (R-SCE-2172190) YPT1 [Golgi membrane] (R-SCE-2422381) YPT1 [Golgi membrane] (R-SCE-2167938) YPT1 [cytosol] (R-SCE-5685727) YPT1 [cytosol] (R-SCE-5685725) YPT1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-SCE-6807766) YPT1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-SCE-6807768) YPT1 [transport vesicle] (R-SCE-6808796) YPT1 [transport vesicle] (R-SCE-6808799) YPT1 [cytosol] (R-SCE-6813902) YPT1 [cytosol] (R-SCE-8873714) YPT1 [cytosol] (R-SCE-8873773) YPT1 [cytosol] (R-SCE-8874038) YPT1 [cytosol] (R-SCE-8870426) YPT1 [cytosol] (R-SCE-8870424) YPT1 [transport vesicle membrane] (R-SCE-8877470) YPT1 [transport vesicle membrane] (R-SCE-8877472) YPT1 [trans-Golgi network membrane] (R-SCE-6814810) YPT1 [endoplasmic reticulum membrane] (R-SCE-6810974)	0.591	3
UniProt:Q04338	3	VTI1 [trans-Golgi network membrane] (R-SCE-6813927) VTI1 [extracellular region] (R-SCE-8862983) VTI1 [platelet alpha granule lumen] (R-SCE-8862964)	0.59	2
UniProt:P43682	1	SFT1 [Golgi membrane] (R-SCE-6807744-2)	0.564	2
UniProt:Q9UI14 PRAF1			0.556	3
UniProt:Q8N6L0 KASH5			0.556	3
UniProt:P22804	4	BET1 [Golgi membrane] (R-SCE-6807744) BET1 [Golgi membrane] (R-SCE-6807743) BET1 [transport vesicle] (R-SCE-6808719) BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-SCE-5688142)	0.527	4
UniProt:P40094	1	COG3 [trans-Golgi network membrane] (R-SCE-6813865)	0.524	4
UniProt:P53271 COG2			0.524	2