Reactome | FUS3 [cytosol]

FUS3 [cytosol]

Stable Identifier

R-SCE-59282

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

MAPK1, P16892

Locations in the PathwayBrowser for interactor UniProt:P23561

Expand all

Signal Transduction (Saccharomyces cerevisiae)

- MAPK family signaling cascades (Saccharomyces cerevisiae)
  - MAPK1/MAPK3 signaling (Saccharomyces cerevisiae)
    - RAF-independent MAPK1/3 activation (Saccharomyces cerevisiae)
      - MAPK1 (ERK2) activation (Saccharomyces cerevisiae)
        
        MAP2K2 binds MAPK1 (Saccharomyces cerevisiae)
        
        FUS3 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P16892

Gene Names

FUS3

Reference Genes

BioGPS Gene:852265 FUS3

ENSEMBL:YBL016W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YBL016W FUS3

Monarch:852265 FUS3

NCBI Gene:852265 FUS3

SGD:YBL016W

Reference Transcript

RefSeq:NM_001178256.1 FUS3

Other Identifiers

1772084_at

2458_g_at

7391_at

852265

GO:0000746

GO:0000750

GO:0001403

GO:0003674

GO:0004672

GO:0004707

GO:0005524

GO:0005575

GO:0005634

GO:0005737

GO:0006468

GO:0007050

GO:0008150

GO:0010468

GO:0010494

GO:0010526

GO:0015031

GO:0016301

GO:0016740

GO:0023052

GO:0030427

GO:0031399

GO:0032196

GO:0042221

GO:0042597

GO:0042802

GO:0043167

GO:0043332

GO:0043409

GO:0043934

GO:0043935

GO:0046777

GO:0046827

GO:0051049

GO:0051169

GO:0051301

GO:0051321

GO:0051726

Participates

as a component of

as an input of

MAP2K2 binds MAPK1 (Saccharomyces cerevisiae)

as a member of

MAPKs [cytosol] (Saccharomyces cerevisiae)

Other forms of this molecule

FUS3 [ficolin-1-rich granule lumen]

FUS3 [extracellular region]

FUS3 [azurophil granule lumen]

phospho-FUS3 [cytosol]

FUS3 [nucleoplasm]

FUS3 [cytosol]

phospho-FUS3 [cytosol]

phospho-FUS3 [nucleoplasm]

Inferred From

MAPK1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_009537.1

PRO

P16892

PDB

2B9J, 2B9F, 2F9G, 2B9H, 2FA2, 2B9I, 2F49

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06784	17	phospho-STE7 [cytosol] (R-SCE-109837) phospho-STE7 [cytosol] (R-SCE-169292) STE7 [cytosol] (R-SCE-59502) phospho-STE7 [cytosol] (R-SCE-112339) phospho-STE7 [cytosol] (R-SCE-112374) STE7 [cytosol] (R-SCE-168107) phospho-STE7 [cytosol] (R-SCE-168170) phospho-STE7 [cytosol] (R-SCE-109848) phospho-STE7 [cytosol] (R-SCE-450353) STE7 [cytosol] (R-SCE-450276) phospho-STE7 [nucleoplasm] (R-SCE-450229) phospho-STE7 [nucleoplasm] (R-SCE-450258) phospho-STE7 [cytosol] (R-SCE-167955) phospho-STE7 [cytosol] (R-SCE-206255) STE7 [cytosol] (R-SCE-168051) STE7 [cytosol] (R-SCE-167998) phospho-STE7 [cytosol] (R-SCE-5674490)	0.932	15
UniProt:P32917 STE5			0.91	11
UniProt:P23561	1	STE11 [cytosol] (R-SCE-167709)	0.721	6
UniProt:P16892	13	FUS3 [ficolin-1-rich granule lumen] (R-SCE-6800964) FUS3 [extracellular region] (R-SCE-6806250) FUS3 [azurophil granule lumen] (R-SCE-6799225) phospho-FUS3 [cytosol] (R-SCE-9635775-2) phospho-FUS3 [cytosol] (R-SCE-9635773) FUS3 [nucleoplasm] (R-SCE-199960) FUS3 [nucleoplasm] (R-SCE-73724-2) FUS3 [cytosol] (R-SCE-59284-2) FUS3 [cytosol] (R-SCE-59282) phospho-FUS3 [cytosol] (R-SCE-109853) phospho-FUS3 [cytosol] (R-SCE-109842-2) phospho-FUS3 [nucleoplasm] (R-SCE-112359-2) phospho-FUS3 [nucleoplasm] (R-SCE-112354)	0.592	2
UniProt:Q12329 HSP42			0.564	2
UniProt:P19882 HSP60	6	HSP60 [mitochondrial matrix] (R-SCE-1252181) HSP60 [mitochondrial inner membrane] (R-SCE-1267982) HSP60 precursor [mitochondrial inner membrane] (R-SCE-1267967) HSP60 precursor [mitochondrial intermembrane space] (R-SCE-1252158) HSP60 [cytosol] (R-SCE-1252153) HSP60 [mitochondrial matrix] (R-SCE-8986171)	0.564	2
UniProt:P15992 HSP26			0.564	2
UniProt:Q03063 DIG1			0.547	2
UniProt:Q03373 DIG2			0.547	2
UniProt:P08539 GPA1			0.544	2
UniProt:P33306 BCK2			0.499	2

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