TRM10 methylates guanosine-9 in tRNA

Stable Identifier
R-SCE-6786632
Type
Reaction [transition]
Species
Saccharomyces cerevisiae
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
TRM10 methylates guanosine-9 in tRNA
TRM10 methylates the 1 position of guanosine at nucleotide 9 of tRNAs (Jackman et al. 2003). In yeast these tRNAs include at least tRNA(Gly), tRNA(Val), tRNA(Trp), tRNA(Pro), tRNA(Met), tRNA(Ile), and tRNA(Arg).
Literature References
PubMed ID Title Journal Year
12702816 Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9

Phizicky, EM, Malik, HS, Jackman, JE, Montange, RK

RNA 2003
Participants
Input
Output
Event Information
Go Biological Process
tRNA modification (0006400)
Catalyst Activity

tRNA (guanine(9)-N(1))-methyltransferase activity of TRM10 [nucleoplasm]

Physical Entity
TRM10 [nucleoplasm] (Saccharomyces cerevisiae)
Activity
tRNA (guanine(9)-N(1))-methyltransferase activity (GO:0052905)
Orthologous Events
TRMT10A methylates guanosine-9 in tRNA (Homo sapiens)
Authored
May, B  (2015-06-30)
Reviewed
Motorin, Y  (2015-08-25)
Jarrous, N  (2015-10-24)
Created
May, B  (2015-07-09)
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