TRM13 methylates the 2' hydroxyl group of cytidine-4 in the acceptor stems of tRNA(Gly) and tRNA(Pro) (Wilkinson et al. 2007). The subcellular location of the reaction is unknown. Yeast lacking TRM13 have no obvious growth defect.
tRNA (cytosine-2'-O-)-methyltransferase activity of TRM13 [cytoplasm]