Reactome | SSA2 [secretory granule lumen]

SSA2 [secretory granule lumen]

Stable Identifier

R-SCE-6801530

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

secretory granule lumen

Synonyms

HSPA8, P10592

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P10592

Gene Names

SSA2

Reference Genes

BioGPS Gene:850636 SSA2

ENSEMBL:YLL024C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YLL024C SSA2

KEGG Gene (Saccharomyces cerevisiae):YLL024C SSA2

Monarch:850636 SSA2

NCBI Gene:850636 SSA2

SGD:YLL024C

Reference Transcript

RefSeq:NM_001181844.1 SSA2

Other Identifiers

10362_at

11317_s_at

1774486_at

850636

GO:0000049

GO:0000166

GO:0000329

GO:0003674

GO:0003723

GO:0005515

GO:0005524

GO:0005575

GO:0005576

GO:0005618

GO:0005634

GO:0005737

GO:0005739

GO:0005773

GO:0005829

GO:0005844

GO:0005886

GO:0006457

GO:0006605

GO:0006616

GO:0008150

GO:0009277

GO:0015031

GO:0015931

GO:0016020

GO:0016787

GO:0016887

GO:0017053

GO:0031072

GO:0035719

GO:0042026

GO:0043161

GO:0043167

GO:0044183

GO:0045892

GO:0051082

GO:0051085

GO:0051169

GO:0051603

GO:0055085

GO:0070482

GO:0090344

GO:0140657

GO:0140662

Participates

as a member of

Secretory granule lumen proteins [secretory granule lumen] (Saccharomyces cerevisiae)

Other forms of this molecule

SSA2 [cytosol]

SSA2 [nucleoplasm]

SSA2 [ficolin-1-rich granule lumen]

SSA2 [extracellular region]

SSA2 [cytosol]

SSA2 [nucleoplasm]

Inferred From

HSPA8 [secretory granule lumen] (Homo sapiens)

Cross References

RefSeq

NP_013076.1

PRO

P10592

Interactors (55)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P22696	2	ESS1 [cytosol] (R-SCE-9626823) ESS1 [nucleoplasm] (R-SCE-936016)	0.702	3
UniProt:P02829	11	HSP90AB1 [secretory granule lumen] (R-SCE-6801477) HSP90AA1 [secretory granule lumen] (R-SCE-6801515) HSP90AB1 [extracellular region] (R-SCE-6806463) HSP90AA1 [extracellular region] (R-SCE-3221946) HSP90AA1 [ficolin-1-rich granule lumen] (R-SCE-6801470) HSP90AB1 [ficolin-1-rich granule lumen] (R-SCE-6801491) HSP90AA1 [plasma membrane] (R-SCE-534996) HSP90AB1 [cytosol] (R-SCE-419617) HSP90AA1 [nucleoplasm] (R-SCE-5082401) HSP90AB1 [nucleoplasm] (R-SCE-5082399) HSP90AA1 [cytosol] (R-SCE-192864)	0.669	3
UniProt:Q12118 SGT2	2	SGT2 [cytosol] (R-SCE-9629049) SGT2 [cytosol] (R-SCE-5423595)	0.669	3
UniProt:P38920	1	MLH1 [nucleoplasm] (R-SCE-912495)	0.592	3
UniProt:Q12189	1	RKI1 [cytosol] (R-SCE-71304)	0.564	2
UniProt:P00546	8	phospho-p-T160-CDK2 [nucleoplasm] (R-SCE-187967) CDK2 [nucleoplasm] (R-SCE-68365) CDK2 [cytosol] (R-SCE-157440) CDK6 [nucleoplasm] (R-SCE-141283) CDK4 [nucleoplasm] (R-SCE-113843) CDK6 [cytosol] (R-SCE-68336) CDK4 [cytosol] (R-SCE-68330) phospho-p-CDK2 [nucleoplasm] (R-SCE-68370)	0.527	3
UniProt:P32469	1	DPH5 [cytosol] (R-SCE-5358485)	0.527	3
UniProt:Q06245	1	SEC10 [cytosol] (R-SCE-265045)	0.527	2
UniProt:P32567	9	phospho-PAH1 [nucleoplasm] (R-SCE-4419936) phospho-PAH1 [nucleoplasm] (R-SCE-4419933) phospho-PAH1 [nucleoplasm] (R-SCE-4419935) PAH1 [nuclear envelope] (R-SCE-4419927) PAH1 [nuclear envelope] (R-SCE-4419928) PAH1 [nuclear envelope] (R-SCE-4419926) PAH1 [endoplasmic reticulum membrane] (R-SCE-549157) PAH1 [endoplasmic reticulum membrane] (R-SCE-549160) PAH1 [endoplasmic reticulum membrane] (R-SCE-549165)	0.527	2
UniProt:P04819	1	LIG1 [nucleoplasm] (R-SCE-53787)	0.527	2
UniProt:P53550	1	DCP2 [cytosol] (R-SCE-429937)	0.527	2
UniProt:P02309	13	HHF2 [nucleoplasm] (R-SCE-4570518) HHF2 [nucleoplasm] (R-SCE-212078) HHF2 [nucleoplasm] (R-SCE-5229015) HHF2 [nucleoplasm] (R-SCE-4754243) HHF2 [nucleoplasm] (R-SCE-4754240) HHF2 [nucleoplasm] (R-SCE-5651656) HHF2 [nucleoplasm] (R-SCE-427469) HHF2 [nucleoplasm] (R-SCE-4568748) HHF2 [nucleoplasm] (R-SCE-4568758) HHF2 [nucleoplasm] (R-SCE-5423110) HHF2 [nucleoplasm] (R-SCE-3451124) HHF2 [nucleoplasm] (R-SCE-181902) HHF2 [nucleoplasm] (R-SCE-5651652)	0.527	3
UniProt:P25694	7	VCP [cytosol] (R-SCE-1181251) VCP [ficolin-1-rich granule lumen] (R-SCE-6800425) VCP [extracellular region] (R-SCE-6806191) VCP [azurophil granule lumen] (R-SCE-6800438) VCP [secretory granule lumen] (R-SCE-6801039) VCP [nucleoplasm] (R-SCE-5643745) Me3K315-VCP [cytosol] (R-SCE-8932209)	0.527	2
UniProt:P28707	2	SBA1 [cytosol] (R-SCE-265269) SBA1 [nucleoplasm] (R-SCE-5082403)	0.527	2
UniProt:Q00955	6	phospho-Btn-p-S222-ACACB [mitochondrial outer membrane] (R-SCE-8876892-2) ACACB [cytosol] (R-SCE-52493-2) Btn-ACACB [mitochondrial outer membrane] (R-SCE-2993858-2) ACACA [cytosol] (R-SCE-1660609) Btn-ACACA [cytosol] (R-SCE-2976730) ACACB [mitochondrial outer membrane] (R-SCE-4167505-2)	0.527	2
UniProt:P20081	1	FPR1 [cytosol] (R-SCE-2026007)	0.527	2
UniProt:Q06682	2	UBX5 [cytosol] (R-SCE-9755305) UBX5 [cytosol] (R-SCE-8956071)	0.527	2
UniProt:P06700	1	SIRT1 [nucleoplasm] (R-SCE-427531)	0.527	2
UniProt:P53256 RRP46	2	RRP46 [nucleoplasm] (R-SCE-6791550) RRP46 [cytosol] (R-SCE-429889)	0.527	2
UniProt:P22147 XRN1	2	XRN1_YEAST [cytosol] (R-SCE-429980) XRN1 [cytosol] (R-SCE-429835)	0.527	2
UniProt:Q03012	1	SPP1 [nucleoplasm] (R-SCE-535610)	0.527	2
UniProt:P25037	2	UBP1 [mitochondrial outer membrane] (R-SCE-5696931) UBP1 [peroxisomal membrane] (R-SCE-9674135)	0.527	2
UniProt:P15705	1	STI1 [cytosol] (R-SCE-443857)	0.527	3
UniProt:P29496 MCM5	2	MCM5 [nucleoplasm] (R-SCE-68551) yMcm5 [nucleoplasm] (R-SCE-169511)	0.527	4
UniProt:P53973	1	HDA1 [cytosol] (R-SCE-5324660)	0.527	2
UniProt:Q06142	4	KAP95 [specific granule lumen] (R-SCE-6799646) KAP95 [extracellular region] (R-SCE-6806306) KAP95 [ficolin-1-rich granule lumen] (R-SCE-6800978) KAP95 [cytosol] (R-SCE-180733)	0.527	2
UniProt:P12385 SUP45	4	Erf-1 [cytosol] (R-SCE-141665) SUP45 [cytosol] (R-SCE-6800157) SUP45 [cytosol] (R-SCE-9629948) SUP45 [cytosol] (R-SCE-54433)	0.527	2
UniProt:P53730	1	ALG12 [endoplasmic reticulum membrane] (R-SCE-449348)	0.527	2
UniProt:P53858	2	BNI4 [plasma membrane] (R-SCE-8848883) BNI4 [platelet alpha granule membrane] (R-SCE-8848893)	0.527	2
UniProt:P34216	2	ITSN2 [cytosol] (R-SCE-8862264) ITSN1 [cytosol] (R-SCE-3006481)	0.527	2
UniProt:P11746	2	phospho-MCM1 [nucleoplasm] (R-SCE-9612518) MCM1 [nucleoplasm] (R-SCE-5666000)	0.527	2
UniProt:P39986	1	ATP13A1 [endoplasmic reticulum membrane] (R-SCE-939749)	0.527	2
UniProt:P17065	2	SEC2 [cytosol] (R-SCE-8875296) SEC2 [cytosol] (R-SCE-5617610)	0.527	2
UniProt:Q03834	1	MSH6 [nucleoplasm] (R-SCE-5357528)	0.527	2
UniProt:P38431	1	EIF5 [cytosol] (R-SCE-72616)	0.527	2
UniProt:P25847	1	MSH2 [nucleoplasm] (R-SCE-5357525)	0.527	2
UniProt:P52917	1	VPS4A [cytosol] (R-SCE-917732)	0.527	2
UniProt:P32447	1	ASF1 [nucleoplasm] (R-SCE-417169)	0.527	2
UniProt:P40344	8	ATG3 [cytosol] (R-SCE-5671860) CysO264-ATG3-MAP1LC3A [cytosol] (R-SCE-9819371) CysO264-ATG3-GABARAP [cytosol] (R-SCE-9819379) CysO264-ATG3-GABARAPL2 [cytosol] (R-SCE-9819376) CysO264-ATG3-MAP1LC3C [cytosol] (R-SCE-9819377) CysO264-ATG3-GABARAPL1 [cytosol] (R-SCE-9819381) CysO264-ATG3-MAP1LC3B [cytosol] (R-SCE-9819365) CysO264-ATG3-GABARAPL3 [cytosol] (R-SCE-5683569)	0.527	2
UniProt:P25357	2	SNT1 [nucleoplasm] (R-SCE-442469) SNT1 [nucleoplasm] (R-SCE-442501)	0.527	2
UniProt:P30771	2	phospho-p-4S-UPF1 [cytosol] (R-SCE-927856) UPF1 [cytosol] (R-SCE-927734)	0.527	2
UniProt:P43593	1	UBP6 [cytosol] (R-SCE-5689541)	0.527	2
UniProt:P25454	2	RAD51 [nucleoplasm] (R-SCE-62637) phospho-p-T309-RAD51 [nucleoplasm] (R-SCE-5685231)	0.527	2
UniProt:P28817	1	HIBCH [mitochondrial matrix] (R-SCE-70872)	0.527	2
UniProt:P34160	2	STO1 [cytosol] (R-SCE-162459) STO1 [nucleoplasm] (R-SCE-51469)	0.527	2
UniProt:Q04458	8	ALDH3A2-2 [cytosol] (R-SCE-9603785) ALDH3A2-2 [peroxisomal membrane] (R-SCE-6811617) ALDH3A1 [cytosol] (R-SCE-5692291) ALDH3B1 [specific granule membrane] (R-SCE-6799510) ALDH3B1 [secretory granule membrane] (R-SCE-6801023) ALDH3B1 [plasma membrane] (R-SCE-5696096) ALDH3A2-1 [endoplasmic reticulum membrane] (R-SCE-6811616) ALDH3B2 [lipid droplet] (R-SCE-6808466)	0.527	2
UniProt:P30822	1	CRM1 [nucleoplasm] (R-SCE-165529)	0.527	2
UniProt:P47047	1	SKIV2L2 [nucleoplasm] (R-SCE-6791189)	0.527	2
UniProt:P54839	2	ERG13 [cytosol] (R-SCE-191329) ERG13 [mitochondrial matrix] (R-SCE-56573)	0.527	3
UniProt:Q99247	1	DUF1 [nucleoplasm] (R-SCE-419549)	0.527	2
UniProt:P54861	2	DNM1L [mitochondrial outer membrane] (R-SCE-351942) DNM1L [cytosol] (R-SCE-351943)	0.527	3
UniProt:P41910	3	phospho-MAF1 [cytosol] (R-SCE-8944455) MAF1 [cytosol] (R-SCE-8944460) MAF1 [nucleoplasm] (R-SCE-8944422)	0.527	2
UniProt:P35845	3	OSBP [cytosol] (R-SCE-429725) OSBPL1A [cytosol] (R-SCE-2213214) OSBPL2 [cytosol] (R-SCE-8867527)	0.527	3
UniProt:P32833 ORC2	2	yORC2 [nucleoplasm] (R-SCE-9749316) ORC2 [nucleoplasm] (R-SCE-68405)	0.527	2
UniProt:P15303	4	phospho-p-S738,T744 SEC23A [cytosol] (R-SCE-5685740) SEC23A [ER to Golgi transport vesicle membrane] (R-SCE-204024) SEC23A [cytosol] (R-SCE-203972) SEC23A [endoplasmic reticulum membrane] (R-SCE-203976)	0.527	2

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