Reactome | Ghost homologue of Ub [nucleoplasm]

Ghost homologue of Ub [nucleoplasm]

Stable Identifier

R-SCE-68524

Type

Genes and Transcripts [GenomeEncodedEntity]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Locations in the PathwayBrowser

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DNA Repair (Saccharomyces cerevisiae)

- Nucleotide Excision Repair (Saccharomyces cerevisiae)
  - Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Saccharomyces cerevisiae)
    - Dual incision in TC-NER (Saccharomyces cerevisiae)
      - 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Saccharomyces cerevisiae)
        
        TC-NER incision complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Saccharomyces cerevisiae)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of Ub [nucleoplasm] (Saccharomyces cerevisiae)
        
        TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of Ub [nucleoplasm] (Saccharomyces cerevisiae)
      - DNA polymerases delta, epsilon or kappa bind the TC-NER site (Saccharomyces cerevisiae)
        
        TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of Ub [nucleoplasm] (Saccharomyces cerevisiae)
        
        TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of Ub [nucleoplasm] (Saccharomyces cerevisiae)
      - ERCC2-facilitated RNA Pol II backtracking in TC-NER (Saccharomyces cerevisiae)
        
        TC-NER pre-incision complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of Ub [nucleoplasm] (Saccharomyces cerevisiae)
        
        TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of Ub [nucleoplasm] (Saccharomyces cerevisiae)
      - ERCC3-facilitated RNA Pol II backtracking in TC-NER (Saccharomyces cerevisiae)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of Ub [nucleoplasm] (Saccharomyces cerevisiae)
        
        TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of Ub [nucleoplasm] (Saccharomyces cerevisiae)
    - Gap-filling DNA repair synthesis and ligation in TC-NER (Saccharomyces cerevisiae)
      - Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Saccharomyces cerevisiae)
        
        TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of Ub [nucleoplasm] (Saccharomyces cerevisiae)
        
        TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of Ub [nucleoplasm] (Saccharomyces cerevisiae)

Participates

as a component of

Inferred From

Ub [nucleoplasm] (Homo sapiens)

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