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PRE6 [cytosol]
Stable Identifier
R-SCE-68736
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
PSMA7, P40303
Locations in the PathwayBrowser
Expand all
Immune System (Saccharomyces cerevisiae)
Adaptive Immune System (Saccharomyces cerevisiae)
Class I MHC mediated antigen processing & presentation (Saccharomyces cerevisiae)
Antigen processing-Cross presentation (Saccharomyces cerevisiae)
Cross-presentation of soluble exogenous antigens (endosomes) (Saccharomyces cerevisiae)
Proteasomal clevage of exogenous antigen (26S proteasome catalyst) (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
20S core particle [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) (Saccharomyces cerevisiae)
Immunoproteasome [cytosol] (Saccharomyces cerevisiae)
20S immunoproteasome core particle [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
ER-Phagosome pathway (Saccharomyces cerevisiae)
Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) (Saccharomyces cerevisiae)
Immunoproteasome [cytosol] (Saccharomyces cerevisiae)
20S immunoproteasome core particle [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
Antigen processing: Ub, ATP-independent proteasomal degradation (Saccharomyces cerevisiae)
Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) (Saccharomyces cerevisiae)
PA28-alpha-beta-20S proteasome [cytosol] (Saccharomyces cerevisiae)
20S core particle [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) (Saccharomyces cerevisiae)
Immunoproteasome [cytosol] (Saccharomyces cerevisiae)
20S immunoproteasome core particle [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
Cytokine Signaling in Immune system (Saccharomyces cerevisiae)
TNFR2 non-canonical NF-kB pathway (Saccharomyces cerevisiae)
26Sproteasome degrades K48polyUb-NIK (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
20S core particle [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
Deubiquitination (Saccharomyces cerevisiae)
Ub-specific processing proteases (Saccharomyces cerevisiae)
ADRM1:26S proteaseome binds USP14 (Saccharomyces cerevisiae)
ADRM1:26S proteasome [cytosol] (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
20S core particle [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
ADRM1:26S proteasome:USP14 [cytosol] (Saccharomyces cerevisiae)
ADRM1:26S proteasome [cytosol] (Saccharomyces cerevisiae)
26S proteasome [cytosol] (Saccharomyces cerevisiae)
20S core particle [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
Proteasome assembly (Saccharomyces cerevisiae)
Formation of the preholoproteasome (Saccharomyces cerevisiae)
Half-proteasome [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
Preholoproteasome [cytosol] (Saccharomyces cerevisiae)
Half-proteasome [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
Formation of the preholothymoproteasome (Saccharomyces cerevisiae)
Half-thymoproteasome [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
Preholothymoproteasome [cytosol] (Saccharomyces cerevisiae)
Half-thymoproteasome [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
Fromation of the preholoimmunoproteasome (Saccharomyces cerevisiae)
Half-immunoproteasome [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
Preholoimmunoproteasome [cytosol] (Saccharomyces cerevisiae)
Half-immunoproteasome [cytosol] (Saccharomyces cerevisiae)
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
PRE6 [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P40303
Gene Names
PRE6
Reference Genes
BioGPS Gene:854119 PRE6
ENSEMBL:YOL038W
KEGG:sce:YOL038W PRE6
Monarch:854119 PRE6
NCBI Gene:854119 PRE6
SGD:YOL038W
UCSC:P40303 PRE6
Reference Transcript
RefSeq:NM_001183292.1 PRE6
Other Identifiers
854119
GO:0000502
GO:0003674
GO:0004175
GO:0004298
GO:0005515
GO:0005575
GO:0005634
GO:0005737
GO:0005739
GO:0005839
GO:0006511
GO:0008233
GO:0010498
GO:0010499
GO:0019773
GO:0034515
GO:0042175
GO:0043161
GO:0051603
Participates
as a component of
20S CP outer ring [cytosol] (Saccharomyces cerevisiae)
Inferred From
PSMA7 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_014604.1
ENSEMBL
YOL038W
,
YOL038W
,
YOL038W_mRNA
PRO
P40303
PDB
5CZ4
,
5D0V
,
4GK7
,
4Y8T
,
7TEO
,
8RHK
,
4QXJ
,
5L5V
,
3MG0
,
6HUC
,
4Y8P
,
4Y80
,
5L60
,
3MG7
,
4QZ1
,
4INT
,
5L5I
,
5L5D
,
6HVV
,
4FZG
,
5L5R
,
6HW0
,
4QZ5
,
6FVU
,
5L6A
,
4Y9Z
,
4HNP
,
4QV6
,
6HWE
,
4QWL
,
4QWU
,
4Y8J
,
6HVA
,
8T08
,
4QW1
,
8U7U
,
5WVI
,
4QW7
,
4NNW
,
5FGG
,
4YA7
,
4R17
,
5A5B
,
2F16
,
6HWC
,
6HVY
,
5L52
,
5MP9
,
1Z7Q
,
6J30
,
6HTD
,
8OI1
,
4Y7X
,
3MG8
,
5DKJ
,
4Y69
,
3WXR
,
5JHS
,
4Y8G
,
5L67
,
3JCP
,
4NNN
,
5L5Q
,
4QLQ
,
1JD2
,
5L5H
,
4INU
,
5CZ7
,
6G8M
,
4Y8K
,
5L63
,
8RVP
,
4QVQ
,
6FVX
,
4HRC
,
3OKJ
,
4QV7
,
4QVW
,
7QO5
,
4NO8
,
8T0M
,
4R18
,
7O2L
,
4YA2
,
4YA9
,
5CGF
,
5L5U
,
6HVX
,
6HW4
,
6HVU
,
5L55
,
8OHZ
,
4Y8U
,
6EF0
,
3E47
,
4Y81
,
4NO1
,
6HW6
,
5L5Y
,
5L62
,
9FSV
,
4QLS
,
3NZW
,
6HWB
,
4QZW
,
3HYE
,
5CZ6
,
4QZ6
,
3UN8
,
7QO3
,
5CGI
,
5L6C
,
6HV5
,
2ZCY
,
8RVQ
,
4QV8
,
3DY3
,
3OEU
,
3MG4
,
4EU2
,
4Y7Y
,
4Y8Q
,
3GPT
,
6J2Q
,
4NO9
,
5FGF
,
5CGH
,
8BW1
,
5FHS
,
5LTT
,
7LSX
,
5L66
,
6HW9
,
9FT0
,
6HW3
,
5L54
,
6J2N
,
6HW5
,
5L5P
,
4RUR
,
3NZX
,
4QZX
,
6HWA
,
4QLT
,
4Y8L
,
4Y74
,
5BXL
,
6HVS
,
5L5J
,
7LS5
,
6FVT
,
4YA3
,
4QWX
,
4HRD
,
3DY4
,
4QWF
,
6H39
,
5JHR
,
4QZ2
,
4Y82
,
4JSU
,
6HTP
,
5WVK
,
5CGG
,
8RVO
,
5FGA
,
6HV3
,
6HUB
,
4QVL
,
4QV1
,
2FAK
,
4QW3
,
5L5T
,
6HUV
,
6HVT
,
7TEJ
,
5D0X
,
6HTC
,
5NIF
,
5MPC
,
6J2C
,
2GPL
,
1FNT
,
5L5X
,
5L61
,
5L5A
,
4QZZ
,
5CZ9
,
5CZA
,
4Y75
,
4QZ7
,
5D0T
,
6HVR
,
3SDI
,
4QLU
,
9GBK
,
5FGE
,
6ZOU
,
6HV4
,
4QUX
,
3OEV
,
4Y8R
,
4Y8H
,
9EY9
,
6EF1
,
4YA4
,
4JT0
,
3GPJ
,
8OLR
,
4LQI
,
4QVM
,
4QV3
,
5BOU
,
4QW4
,
6FVW
,
4Y70
,
3SDK
,
5L65
,
5CZ5
,
6HUU
,
8RHL
,
4X6Z
,
5MPA
,
4Z1L
,
6HTR
,
5D0Z
,
5L69
,
4CR3
,
6G7F
,
1RYP
,
5DKI
,
4Y6V
,
3TDD
,
4QBY
,
4Y8M
,
4G4S
,
4Y84
,
5L5B
,
6HW8
,
4R00
,
4QLV
,
5FGD
,
4R02
,
6ZP6
,
4QV9
,
4QWG
,
4QV0
,
4QZ3
,
4QWJ
,
6EF2
,
6J2X
,
4YA5
,
4JSQ
,
4QVN
,
4QW5
,
5FGI
,
7LS6
,
5LAI
,
4LTC
,
3NZJ
,
6HTB
,
5D0W
,
8RHJ
,
9FST
,
4INR
,
3BDM
,
4Y77
,
3SHJ
,
3JCO
,
4QZ0
,
5BXN
,
4Y8N
,
3UN4
,
5L5Z
,
5L5S
,
6HVW
,
5D0S
,
9FT1
,
5L5E
,
9D0T
,
4QV4
,
6FVY
,
6HWF
,
4QUY
,
1G0U
,
4QWI
,
5AHJ
,
6ZP8
,
4QWR
,
4Y6A
,
4Y8I
,
1G65
,
6EF3
,
5FG7
,
4QW0
,
4YA0
,
8RVL
,
4QW6
,
6HV7
,
4J70
,
4Y6Z
,
6HUQ
,
3D29
,
6HWD
,
8U6Y
,
6GOP
,
4Q1S
,
5MPB
,
4Y8S
,
5L5O
,
5L68
,
4CR4
,
4QVY
,
4Y78
,
4Y7W
,
4Y8O
,
5L5F
,
3MG6
,
4V7O
,
5CZ8
,
4FZC
,
5M2B
,
6G8N
,
6HW7
,
5L64
,
5L6B
,
5LAJ
,
4Y9Y
,
4QV5
,
4QWK
,
4QWS
,
4QZ4
,
4CR2
,
5L5W
,
4NO6
,
4QVP
,
5FG9
,
4QVV
,
3GPW
,
4YA1
,
6FVV
,
5FGH
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P53549
1
RPT4 [cytosol]
(R-SCE-68783)
0.638
3
UniProt:P43588
4
RPN11 [cytosol]
(R-SCE-68722)
RPN11 [secretory granule lumen]
(R-SCE-6800926)
RPN11 [extracellular region]
(R-SCE-6806511)
RPN11 [ficolin-1-rich granule lumen]
(R-SCE-6800419)
0.564
2
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:Q08723
4
RPN8 [cytosol]
(R-SCE-68806)
RPN8 [secretory granule lumen]
(R-SCE-6801008)
RPN8 [extracellular region]
(R-SCE-6806488)
RPN8 [ficolin-1-rich granule lumen]
(R-SCE-6800406)
0.527
2
UniProt:P32589
5
SSE1 [nucleoplasm]
(R-SCE-5252053)
SSE1 [nucleoplasm]
(R-SCE-5251998)
SSE1 [cytosol]
(R-SCE-5251943)
SSE1 [cytosol]
(R-SCE-5251946)
SSE1 [cytosol]
(R-SCE-3299412)
0.527
2
UniProt:Q12377
4
RPN6 [cytosol]
(R-SCE-68790)
RPN6 [secretory granule lumen]
(R-SCE-6800943)
RPN6 [extracellular region]
(R-SCE-6806441)
RPN6 [ficolin-1-rich granule lumen]
(R-SCE-6800436)
0.527
2
UniProt:P38886
1
RPN10 [cytosol]
(R-SCE-68800)
0.527
2
UniProt:Q12250
4
RPN5 [cytosol]
(R-SCE-68792)
RPN5 [secretory granule lumen]
(R-SCE-6800934)
RPN5 [extracellular region]
(R-SCE-6806480)
RPN5 [ficolin-1-rich granule lumen]
(R-SCE-6800416)
0.527
2
UniProt:Q04062
4
RPN9 [cytosol]
(R-SCE-68794)
RPN9 [secretory granule lumen]
(R-SCE-6800983)
RPN9 [extracellular region]
(R-SCE-6806469)
RPN9 [ficolin-1-rich granule lumen]
(R-SCE-6800413)
0.527
2
UniProt:P33298
1
RPT3 [cytosol]
(R-SCE-68777)
0.527
2
UniProt:P33299
4
RPT1 [cytosol]
(R-SCE-68771)
RPT1 [secretory granule lumen]
(R-SCE-6800994)
RPT1 [extracellular region]
(R-SCE-6806472)
RPT1 [ficolin-1-rich granule lumen]
(R-SCE-6800421)
0.527
2
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