Reactome | RPN8 [cytosol]

RPN8 [cytosol]

Stable Identifier

R-SCE-68806

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

PSMD7, Q08723

Locations in the PathwayBrowser for interactor UniProt:Q12250

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External Reference Information

External Reference

UniProt:Q08723

Gene Names

RPN8

Reference Genes

BioGPS Gene:854435 RPN8

ENSEMBL:YOR261C

KEGG:sce:YOR261C RPN8

Monarch:854435 RPN8

NCBI Gene:854435 RPN8

SGD:YOR261C

UCSC:Q08723 RPN8

Reference Transcript

RefSeq:NM_001183680.3 RPN8

Other Identifiers

1774707_at

8282_at

854435

GO:0000502

GO:0003674

GO:0005515

GO:0005575

GO:0005737

GO:0005838

GO:0006511

GO:0008150

GO:0008233

GO:0008237

GO:0008541

GO:0016787

GO:0034515

GO:0043161

GO:0051603

Participates

as an input of

Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Saccharomyces cerevisiae)

as a component of

PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Saccharomyces cerevisiae)

Other forms of this molecule

RPN8 [secretory granule lumen]

RPN8 [extracellular region]

RPN8 [ficolin-1-rich granule lumen]

Inferred From

PSMD7 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_014904.3

ENSEMBL

YOR261C_mRNA

PRO

Q08723

PDB

3JCO, 4CR3, 5MPB, 6J2N, 5MPC, 3JCP, 6J30, 4CR4, 6FVV, 6FVW, 6FVU, 6FVT, 4OCM, 5WVK, 7QO3, 4OCN, 4OWP, 4O8Y, 5W83, 5WVI, 4CR2, 4OCL, 3J47, 7QO5, 6J2C, 5MPE, 6J2Q, 4O8X, 7QO6, 5MPD, 6J2X, 3JCK, 5U4P, 6FVX, 6FVY, 5A5B

Interactors (30)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P43588	4	PSMD14 [cytosol] (R-SCE-68722) PSMD14 [secretory granule lumen] (R-SCE-6800926) PSMD14 [extracellular region] (R-SCE-6806511) PSMD14 [ficolin-1-rich granule lumen] (R-SCE-6800419)	0.928	22
UniProt:Q12250	4	RPN5 [cytosol] (R-SCE-68792) RPN5 [secretory granule lumen] (R-SCE-6800934) RPN5 [extracellular region] (R-SCE-6806480) RPN5 [ficolin-1-rich granule lumen] (R-SCE-6800416)	0.91	27
UniProt:Q04062	4	RPN9 [cytosol] (R-SCE-68794) RPN9 [secretory granule lumen] (R-SCE-6800983) RPN9 [extracellular region] (R-SCE-6806469) RPN9 [ficolin-1-rich granule lumen] (R-SCE-6800413)	0.863	16
UniProt:Q12377	4	RPN6 [cytosol] (R-SCE-68790) RPN6 [secretory granule lumen] (R-SCE-6800943) RPN6 [extracellular region] (R-SCE-6806441) RPN6 [ficolin-1-rich granule lumen] (R-SCE-6800436)	0.818	31
UniProt:P32496	1	RPN12 [cytosol] (R-SCE-68808)	0.818	10
UniProt:P38764	4	RPN1 [cytosol] (R-SCE-68796) RPN1 [secretory granule lumen] (R-SCE-6800919) RPN1 [extracellular region] (R-SCE-6806479) RPN1 [ficolin-1-rich granule lumen] (R-SCE-6800435)	0.813	25
UniProt:P50086 PSD10			0.784	7
UniProt:P40016	4	RPN3 [cytosol] (R-SCE-68798) RPN3 [secretory granule lumen] (R-SCE-6800873) RPN3 [extracellular region] (R-SCE-6806443) RPN3 [ficolin-1-rich granule lumen] (R-SCE-6800408)	0.77	21
UniProt:P43593	1	UBP6 [cytosol] (R-SCE-5689541)	0.758	17
UniProt:P32565	3	RPN2 [cytosol] (R-SCE-68786) RPN2 [azurophil granule lumen] (R-SCE-6798741) RPN2 [extracellular region] (R-SCE-6806194)	0.758	17
UniProt:P38348 HSM3			0.758	5
UniProt:P38886 RPN10			0.744	12
UniProt:Q06103	4	RPN7 [cytosol] (R-SCE-68804) RPN7 [secretory granule lumen] (R-SCE-6801036) RPN7 [extracellular region] (R-SCE-6806486) RPN7 [ficolin-1-rich granule lumen] (R-SCE-6800440)	0.744	12
UniProt:P53196 RPN14			0.708	4
UniProt:P38737 ECM29			0.69	5
UniProt:Q01939	1	PSMC5 [cytosol] (R-SCE-68780)	0.688	18
UniProt:P33299	4	PSMC2 [cytosol] (R-SCE-68771) PSMC2 [secretory granule lumen] (R-SCE-6800994) PSMC2 [extracellular region] (R-SCE-6806472) PSMC2 [ficolin-1-rich granule lumen] (R-SCE-6800421)	0.669	9
UniProt:P33298	1	PSMC4 [cytosol] (R-SCE-68777)	0.669	8
UniProt:O13563 RPN13			0.669	5
UniProt:P53549	1	PSMC6 [cytosol] (R-SCE-68783)	0.667	8
UniProt:P33297	4	PSMC3 [cytosol] (R-SCE-68774) PSMC3 [secretory granule lumen] (R-SCE-6800917) PSMC3 [extracellular region] (R-SCE-6806496) PSMC3 [ficolin-1-rich granule lumen] (R-SCE-6800429)	0.564	7
UniProt:O94742 SEM1			0.564	15
UniProt:P40327	1	PSMC1 [cytosol] (R-SCE-68768)	0.564	10
UniProt:P12753 RAD50	1	DNA repair protein RAD50 [nucleoplasm] (R-SCE-981774)	0.527	2
UniProt:P32628	2	RAD23 [nucleoplasm] (R-SCE-62590) RAD23 [nucleoplasm] (R-SCE-5688076)	0.527	2
UniProt:P10591	17	SSA1 [cytosol] (R-SCE-3371410-2) SSA1 [cytosol] (R-SCE-3371408-2) SSA1 [cytosol] (R-SCE-6792602-2) SSA1 [secretory granule lumen] (R-SCE-6801472-2) SSA1 [extracellular region] (R-SCE-6806500-2) SSA1 [ficolin-1-rich granule lumen] (R-SCE-6801512-2) SSA1 [ficolin-1-rich granule lumen] (R-SCE-6801496-2) SSA1 [extracellular region] (R-SCE-6805872-2) SSA1 [nucleoplasm] (R-SCE-6792605-2) SSA1 [nucleoplasm] (R-SCE-912480-2) SSA1 [nucleoplasm] (R-SCE-5082367-2) SSA1 [nucleoplasm] (R-SCE-5252082-2) SSA1 [nucleoplasm] (R-SCE-5252088-2) SSA1 [nucleoplasm] (R-SCE-5252009-2) SSA1 [cytosol] (R-SCE-5251948-2) SSA1 [cytosol] (R-SCE-5251981-2) SSA1 [cytosol] (R-SCE-3371521-2)	0.527	2
UniProt:P40303	1	PRE6 [cytosol] (R-SCE-68736)	0.527	2
UniProt:P40302	1	PRE5 [cytosol] (R-SCE-68724)	0.527	2
UniProt:P23638	1	PRE9 [cytosol] (R-SCE-68730)	0.527	2
UniProt:P30657	2	PRE4 [cytosol] (R-SCE-68750) PRE4 [cytosol] (R-SCE-9908138)	0.527	2

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