Reactome | RPN12 [cytosol]

RPN12 [cytosol]

Stable Identifier

R-SCE-68808

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

PSMD8, P32496

Locations in the PathwayBrowser for interactor UniProt:P38737 ECM29

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External Reference Information

External Reference

UniProt:P32496

Gene Names

RPN12

Reference Genes

BioGPS Gene:850613 RPN12

ENSEMBL:YFR052W

KEGG:sce:YFR052W RPN12

Monarch:850613 RPN12

NCBI Gene:850613 RPN12

SGD:YFR052W

UCSC:P32496 RPN12

Reference Transcript

RefSeq:NM_001180017.1 RPN12

Other Identifiers

1777244_at

5306_at

850613

GO:0000502

GO:0003674

GO:0005515

GO:0005575

GO:0005634

GO:0005737

GO:0005829

GO:0005838

GO:0006508

GO:0006511

GO:0006807

GO:0008150

GO:0008541

GO:0034515

GO:0043161

GO:0043170

GO:0043248

GO:0044238

GO:0051603

Participates

as an input of

Formation of the 19S regulatory particle lid (Saccharomyces cerevisiae)

as a component of

19S RP lid [cytosol] (Saccharomyces cerevisiae)

Inferred From

PSMD8 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_116710.1

ENSEMBL

YFR052W, YFR052W_mRNA, YFR052W

PRO

P32496

PDB

3JCK, 7QO3, 5A5B, 6FVY, 6FVX, 6FVW, 6FVV, 6FVT, 6FVU, 5WVK, 6J2Q, 6J2X, 4CR2, 7QO5, 5WVI, 4CR4, 5MPC, 5MPB, 3JCP, 6J2N, 6J2C, 3JCO, 4CR3, 6J30, 5MPE, 5MPD, 3J47

Interactors (29)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q01939	1	PSMC5 [cytosol] (R-SCE-68780)	0.822	11
UniProt:Q08723	4	RPN8 [cytosol] (R-SCE-68806) RPN8 [ficolin-1-rich granule lumen] (R-SCE-6800406) RPN8 [extracellular region] (R-SCE-6806488) RPN8 [secretory granule lumen] (R-SCE-6801008)	0.818	10
UniProt:P38764	4	RPN1 [cytosol] (R-SCE-68796) RPN1 [ficolin-1-rich granule lumen] (R-SCE-6800435) RPN1 [extracellular region] (R-SCE-6806479) RPN1 [secretory granule lumen] (R-SCE-6800919)	0.813	18
UniProt:P38886 RPN10			0.813	10
UniProt:Q12250	4	RPN5 [cytosol] (R-SCE-68792) RPN5 [ficolin-1-rich granule lumen] (R-SCE-6800416) RPN5 [extracellular region] (R-SCE-6806480) RPN5 [secretory granule lumen] (R-SCE-6800934)	0.802	16
UniProt:Q06103	4	RPN7 [cytosol] (R-SCE-68804) RPN7 [ficolin-1-rich granule lumen] (R-SCE-6800440) RPN7 [extracellular region] (R-SCE-6806486) RPN7 [secretory granule lumen] (R-SCE-6801036)	0.802	10
UniProt:P53549	1	PSMC6 [cytosol] (R-SCE-68783)	0.745	4
UniProt:P43588	4	PSMD14 [cytosol] (R-SCE-68722) PSMD14 [ficolin-1-rich granule lumen] (R-SCE-6800419) PSMD14 [extracellular region] (R-SCE-6806511) PSMD14 [secretory granule lumen] (R-SCE-6800926)	0.744	7
UniProt:P33298	1	PSMC4 [cytosol] (R-SCE-68777)	0.738	4
UniProt:P38737 ECM29			0.69	5
UniProt:P38348 HSM3			0.688	3
UniProt:Q12377	4	RPN6 [cytosol] (R-SCE-68790) RPN6 [ficolin-1-rich granule lumen] (R-SCE-6800436) RPN6 [extracellular region] (R-SCE-6806441) RPN6 [secretory granule lumen] (R-SCE-6800943)	0.669	12
UniProt:Q04062	4	RPN9 [cytosol] (R-SCE-68794) RPN9 [ficolin-1-rich granule lumen] (R-SCE-6800413) RPN9 [extracellular region] (R-SCE-6806469) RPN9 [secretory granule lumen] (R-SCE-6800983)	0.669	8
UniProt:P32565	3	RPN2 [cytosol] (R-SCE-68786) RPN2 [azurophil granule lumen] (R-SCE-6798741) RPN2 [extracellular region] (R-SCE-6806194)	0.669	11
UniProt:P33299	4	PSMC2 [cytosol] (R-SCE-68771) PSMC2 [ficolin-1-rich granule lumen] (R-SCE-6800421) PSMC2 [extracellular region] (R-SCE-6806472) PSMC2 [secretory granule lumen] (R-SCE-6800994)	0.669	4
UniProt:P40327	1	PSMC1 [cytosol] (R-SCE-68768)	0.669	4
UniProt:P40016	4	RPN3 [cytosol] (R-SCE-68798) RPN3 [ficolin-1-rich granule lumen] (R-SCE-6800408) RPN3 [extracellular region] (R-SCE-6806443) RPN3 [secretory granule lumen] (R-SCE-6800873)	0.669	8
UniProt:P53196 RPN14			0.623	3
UniProt:P50086 PSD10			0.623	3
UniProt:P43593	1	UBP6 [cytosol] (R-SCE-5689541)	0.564	13
UniProt:O94742 SEM1			0.564	16
UniProt:P33297	4	PSMC3 [cytosol] (R-SCE-68774) PSMC3 [ficolin-1-rich granule lumen] (R-SCE-6800429) PSMC3 [extracellular region] (R-SCE-6806496) PSMC3 [secretory granule lumen] (R-SCE-6800917)	0.527	2
UniProt:P32628	2	RAD23 [nucleoplasm] (R-SCE-62590) RAD23 [nucleoplasm] (R-SCE-5688076)	0.527	2
UniProt:P32589	5	SSE1 [nucleoplasm] (R-SCE-5252053) SSE1 [nucleoplasm] (R-SCE-5251998) SSE1 [cytosol] (R-SCE-5251943) SSE1 [cytosol] (R-SCE-5251946) SSE1 [cytosol] (R-SCE-3299412)	0.527	2
UniProt:P11484	17	HSPA1L [cytosol] (R-SCE-3371410-4) HSPA2 [cytosol] (R-SCE-3371408-4) HSPA1A [cytosol] (R-SCE-6792602-4) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-4) HSPA1A [extracellular region] (R-SCE-6805872-4) HSPA6 [extracellular region] (R-SCE-6806500-4) HSPA6 [secretory granule lumen] (R-SCE-6801472-4) HSPA1A [nucleoplasm] (R-SCE-6792605-4) HSPA2 [nucleoplasm] (R-SCE-912480-4) HSPA1L [nucleoplasm] (R-SCE-5082367-4) HSPA14 [nucleoplasm] (R-SCE-5252082-4) HSPA6 [nucleoplasm] (R-SCE-5252088-4) HSPA13 [nucleoplasm] (R-SCE-5252009-4) HSPA14 [cytosol] (R-SCE-5251948-4) HSPA13 [cytosol] (R-SCE-5251981-4) HSPA6 [cytosol] (R-SCE-3371521-4)	0.527	2
UniProt:P40302	1	PRE5 [cytosol] (R-SCE-68724)	0.527	2
UniProt:O13563 RPN13			0.527	2
UniProt:P22141	1	PRE1 [cytosol] (R-SCE-68744)	0.527	2
UniProt:P43583 BLM10			0.508	2

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