Reactome | GCD7 [cytosol]

GCD7 [cytosol]

Stable Identifier

R-SCE-72519

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

EIF2B2, P32502

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P32502

Gene Names

GCD7

Reference Genes

BioGPS Gene:850998 GCD7

ENSEMBL:YLR291C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YLR291C GCD7

KEGG Gene (Saccharomyces cerevisiae):YLR291C GCD7

Monarch:850998 GCD7

NCBI Gene:850998 GCD7

SGD:YLR291C

Reference Transcript

RefSeq:NM_001182179.1 GCD7

Other Identifiers

10051_at

1771830_at

850998

GO:0003674

GO:0003743

GO:0005085

GO:0005515

GO:0005575

GO:0005737

GO:0005739

GO:0005829

GO:0005851

GO:0006412

GO:0006413

GO:0006417

GO:0006446

GO:0008135

GO:0008150

GO:0030234

GO:0032045

GO:0043547

GO:0044237

GO:1901566

Participates

as a component of

eIF2B subunits complex [cytosol] (Saccharomyces cerevisiae)

Inferred From

EIF2B2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_013394.1

PRO

P32502

PDB

6QG0, 6QG2, 6QG5, 6I3M, 6QG6, 6QG1, 6QG3, 6I7T

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13490 BIRC2	5	K63polyUb-BIRC2 [cytosol] (R-HSA-5668512) BIRC2(1-372) [cytosol] (R-HSA-202913) BIRC2(373-618) [cytosol] (R-HSA-202931) K48pUb-BIRC2 [cytosol] (R-HSA-5675479) BIRC2 [cytosol] (R-HSA-50847)	0.556	3
UniProt:P55212 CASP6	5	CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(194-293) [cytosol] (R-HSA-266128) CASP6 (1-293) [cytosol] (R-HSA-6798132)	0.556	3
UniProt:Q9UNE7 STUB1	1	STUB1 [cytosol] (R-HSA-975970)	0.556	3
UniProt:O96006 ZBED1	1	ZBED1 [nucleoplasm] (R-HSA-8956376)	0.556	3
UniProt:P14373 TRIM27	2	TRIM27 [nucleoplasm] (R-HSA-2997690) TRIM27 [cytosol] (R-HSA-8851002)	0.556	3
UniProt:P04271 S100B	1	S100B [extracellular region] (R-HSA-879433)	0.556	3
UniProt:O14641 DVL2	5	pp-DVL2 [cytosol] (R-HSA-3772398) p-DVL2 [cytosol] (R-HSA-201706) p-DVL2 [clathrin-coated endocytic vesicle] (R-HSA-5138444) DVL2 [cytosol] (R-HSA-201694) ub-DVL2 [cytosol] (R-HSA-4652689)	0.556	3
UniProt:Q9H0E2 TOLLIP	4	TOLLIP [cytosol] (R-HSA-446885) TOLLIP [azurophil granule lumen] (R-HSA-6799709) TOLLIP [extracellular region] (R-HSA-6800448) TOLLIP [specific granule lumen] (R-HSA-6799719)	0.556	3
UniProt:O43597 SPRY2	8	p-S111,S120-SPRY2 [cytosol] (R-HSA-1295590) p-Y55-SPRY2 [cytosol] (R-HSA-182950) SPRY2 [plasma membrane] (R-HSA-182924) SPRY2 [cytosol] (R-HSA-182949) p-S112,S115-SPRY2 [cytosol] (R-HSA-1295619) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-934555) p-S112,S121-SPRY2 [plasma membrane] (R-HSA-934595) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-1295629)	0.556	3
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.556	3
UniProt:P14174 MIF	3	MIF [secretory granule lumen] (R-HSA-6803282) MIF [extracellular region] (R-HSA-212594) MIF [ficolin-1-rich granule lumen] (R-HSA-6803289)	0.556	3
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.556	3
UniProt:P98170 XIAP	3	K48pUb-XIAP [cytosol] (R-HSA-5675477) XIAP [nucleoplasm] (R-HSA-3322366) XIAP [cytosol] (R-HSA-50849)	0.556	3
UniProt:P49247 RPIA	2	RPIA [cytosol] (R-HSA-71304) RPIA A61V [cytosol] (R-HSA-5660009)	0.556	3
UniProt:Q9Y6D9 MAD1L1	1	MAD1L1 [cytosol] (R-HSA-141433)	0.556	3
UniProt:P63279 UBE2I	9	monoSUMO1-K14-UBE2I [nucleoplasm] (R-HSA-4085358) UBE2I [nuclear envelope] (R-HSA-4655408) SUMO3-C93-UBE2I [nucleoplasm] (R-HSA-3730629) SUMO2-C93-UBE2I [cytosol] (R-HSA-4656944) UBE2I [cytosol] (R-HSA-4655342) SUMO1-C93-UBE2I [cytosol] (R-HSA-4656909) SUMO1-C93-UBE2I [nucleoplasm] (R-HSA-3730617) UBE2I [nucleoplasm] (R-HSA-912481) SUMO2-C93-UBE2I [nucleoplasm] (R-HSA-3730619)	0.556	3

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