Reactome | NAM7 [cytosol]

NAM7 [cytosol]

Stable Identifier

R-SCE-927734

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

UPF1, P30771

Locations in the PathwayBrowser for interactor UniProt:P53550

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External Reference Information

External Reference

UniProt:P30771

Gene Names

NAM7

Reference Genes

BioGPS Gene:855104 NAM7

ENSEMBL:YMR080C

KEGG:sce:YMR080C NAM7

Monarch:855104 NAM7

NCBI Gene:855104 NAM7

SGD:YMR080C

UCSC:P30771 NAM7

Reference Transcript

RefSeq:NM_001182579.1 NAM7

Other Identifiers

855104

GO:0000166

GO:0000184

GO:0000956

GO:0003674

GO:0003677

GO:0003678

GO:0003697

GO:0003723

GO:0003724

GO:0003729

GO:0004386

GO:0005524

GO:0005634

GO:0005737

GO:0005844

GO:0006310

GO:0006325

GO:0006401

GO:0006417

GO:0006449

GO:0008150

GO:0008270

GO:0008298

GO:0016567

GO:0016787

GO:0016887

GO:0030466

GO:0036121

GO:0043024

GO:0043167

GO:0046872

GO:0070478

GO:0070647

GO:0071026

GO:0140657

Participates

as an output of

Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Saccharomyces cerevisiae)

as a component of

as an input of

Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Saccharomyces cerevisiae)

Other forms of this molecule

phospho-NAM7 [cytosol]

Inferred From

UPF1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_013797.1

ENSEMBL

YMR080C, YMR080C, YMR080C_mRNA

IntEnz

3.6.4.13

PRO

P30771

PDB

2XZL, 8RD3

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53550	1	DCP2 [cytosol] (R-SCE-429937)	0.659	4
UniProt:P07246 ADH3			0.592	5
UniProt:Q12129 NMD4			0.564	2
UniProt:P38798	1	NMD2 [cytosol] (R-SCE-927799)	0.547	2
UniProt:P39517	1	DHH1 [cytosol] (R-SCE-430032)	0.547	3
UniProt:P38788	20	SSZ1 [nucleoplasm] (R-SCE-8932217-6) SSZ1 [cytosol] (R-SCE-5251954-6) SSZ1 [cytosol] (R-SCE-3371521-6) SSZ1 [cytosol] (R-SCE-5251981-6) SSZ1 [cytosol] (R-SCE-5251948-6) SSZ1 [nucleoplasm] (R-SCE-5252047-6) SSZ1 [nucleoplasm] (R-SCE-5252009-6) SSZ1 [nucleoplasm] (R-SCE-5252088-6) SSZ1 [nucleoplasm] (R-SCE-5252082-6) SSZ1 [nucleoplasm] (R-SCE-5082367-6) SSZ1 [nucleoplasm] (R-SCE-912480-6) SSZ1 [ficolin-1-rich granule lumen] (R-SCE-6801494-6) SSZ1 [ficolin-1-rich granule lumen] (R-SCE-6801512-6) SSZ1 [extracellular region] (R-SCE-6806500-6) SSZ1 [extracellular region] (R-SCE-6805936-6) SSZ1 [secretory granule lumen] (R-SCE-6801530-6) SSZ1 [secretory granule lumen] (R-SCE-6801472-6) SSZ1 [nucleoplasm] (R-SCE-5082380-6) SSZ1 [cytosol] (R-SCE-3371408-6) SSZ1 [cytosol] (R-SCE-3371410-6)	0.527	3
UniProt:P33892 GCN1	1	GCN1 [cytosol] (R-SCE-9633502)	0.527	2
UniProt:P10592	20	SSA2 [cytosol] (R-SCE-264476-3) SSA2 [nucleoplasm] (R-SCE-6792605) SSA2 [cytosol] (R-SCE-3371410-3) SSA2 [cytosol] (R-SCE-3371408-3) SSA2 [cytosol] (R-SCE-6792602) SSA2 [nucleoplasm] (R-SCE-5082380-3) SSA2 [secretory granule lumen] (R-SCE-6801472-3) SSA2 [secretory granule lumen] (R-SCE-6801530-3) SSA2 [extracellular region] (R-SCE-6805936-3) SSA2 [extracellular region] (R-SCE-6806500-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801496) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494-3) SSA2 [extracellular region] (R-SCE-6805872) SSA2 [nucleoplasm] (R-SCE-912480-3) SSA2 [nucleoplasm] (R-SCE-5082367-3) SSA2 [nucleoplasm] (R-SCE-5252082-3) SSA2 [nucleoplasm] (R-SCE-5252088-3) SSA2 [nucleoplasm] (R-SCE-5252009-3) SSA2 [nucleoplasm] (R-SCE-5252047-3)	0.527	2
UniProt:Q01477	3	UBP3 [cytosol] (R-SCE-6782974) UBP3 [cytosol] (R-SCE-6782986) UBP3 [nucleoplasm] (R-SCE-3222218)	0.527	2
UniProt:P49723 RIR4			0.527	2
UniProt:P06169 PDC1			0.527	2
UniProt:P07149 FAS1			0.527	2
UniProt:P32324 EFT1	11	EFT1; EFT2 [secretory granule lumen] (R-SCE-6801504) EFT1; EFT2 [extracellular region] (R-SCE-6806499) EFT1; EFT2 [ficolin-1-rich granule lumen] (R-SCE-6801513) EFT1; EFT2 [cytosol] (R-SCE-156901) EFT1; EFT2 [cytosol] (R-SCE-5358478) EFT1; EFT2 [cytosol] (R-SCE-5367025) EFT1; EFT2 [cytosol] (R-SCE-5358472) EFT1; EFT2 [cytosol] (R-SCE-5358501) Me-diphthine EFT1 [cytosol] (R-SCE-5367013) diphthine EFT1 [cytosol] (R-SCE-5367015) EFT1; EFT2 [cytosol] (R-SCE-8932237)	0.527	2
UniProt:P32589	5	SSE1 [nucleoplasm] (R-SCE-5252053) SSE1 [nucleoplasm] (R-SCE-5251998) SSE1 [cytosol] (R-SCE-5251943) SSE1 [cytosol] (R-SCE-5251946) SSE1 [cytosol] (R-SCE-3299412)	0.527	4
UniProt:P22147 XRN1	2	XRN1 [cytosol] (R-SCE-429835) XRN1_YEAST [cytosol] (R-SCE-429980)	0.527	2
UniProt:P30822	2	CRM1 [cytosol] (R-SCE-165539) CRM1 [nucleoplasm] (R-SCE-165529)	0.527	2

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