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phospho-p-4S-UPF1 [cytosol]
Stable Identifier
R-SCE-927856
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
P30771
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Saccharomyces cerevisiae)
Nonsense-Mediated Decay (NMD) (Saccharomyces cerevisiae)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Saccharomyces cerevisiae)
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Saccharomyces cerevisiae)
mRNA Cleaved by SMG6 [cytosol] (Saccharomyces cerevisiae)
phospho-p-4S-UPF1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-4S-UPF1 [cytosol] (Saccharomyces cerevisiae)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Saccharomyces cerevisiae)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
phospho-p-4S-UPF1 [cytosol] (Saccharomyces cerevisiae)
SMG6 hydrolyzes mRNA with premature termination codon (Saccharomyces cerevisiae)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
phospho-p-4S-UPF1 [cytosol] (Saccharomyces cerevisiae)
mRNA Cleaved by SMG6 [cytosol] (Saccharomyces cerevisiae)
phospho-p-4S-UPF1 [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P30771
Reference Genes
BioGPS Gene:855104
ENSEMBL:YMR080C
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YMR080C
Monarch:855104
NCBI Gene:855104
SGD:YMR080C
Reference Transcript
RefSeq:NM_001182579.1
Other Identifiers
1777049_at
855104
9566_at
GO:0000166
GO:0000184
GO:0000932
GO:0000956
GO:0003674
GO:0003677
GO:0003697
GO:0003723
GO:0003724
GO:0003729
GO:0004004
GO:0004386
GO:0005524
GO:0005575
GO:0005634
GO:0005737
GO:0005829
GO:0005844
GO:0005886
GO:0006310
GO:0006325
GO:0006401
GO:0006417
GO:0006449
GO:0008150
GO:0008270
GO:0008298
GO:0009611
GO:0009863
GO:0009867
GO:0010182
GO:0010468
GO:0016020
GO:0016567
GO:0016787
GO:0016887
GO:0023052
GO:0030466
GO:0032508
GO:0036121
GO:0042221
GO:0042742
GO:0043024
GO:0043167
GO:0046872
GO:0048571
GO:0070478
GO:0070647
GO:0071026
GO:0140657
Participates
as a component of
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
mRNA Cleaved by SMG6 [cytosol] (Saccharomyces cerevisiae)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
This entity regulates
Positively
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex
(Saccharomyces cerevisiae)
Other forms of this molecule
UPF1 [cytosol]
Inferred From
p-4S-UPF1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 1089 (in Homo sapiens)
Coordinate
1089
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1107 (in Homo sapiens)
Coordinate
1107
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1084 (in Homo sapiens)
Coordinate
1084
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1127 (in Homo sapiens)
Coordinate
1127
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_013797.1
IntEnz
3.6.4.13
PRO
P30771
PDB
2XZL
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P10592
20
SSA2 [cytosol]
(R-SCE-264476)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801512-3)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801496-3)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801494)
SSA2 [extracellular region]
(R-SCE-6805872-3)
SSA2 [extracellular region]
(R-SCE-6806500-3)
SSA2 [extracellular region]
(R-SCE-6805936)
SSA2 [secretory granule lumen]
(R-SCE-6801530)
SSA2 [secretory granule lumen]
(R-SCE-6801472-3)
SSA2 [cytosol]
(R-SCE-3371410-3)
SSA2 [cytosol]
(R-SCE-3371408-3)
SSA2 [cytosol]
(R-SCE-6792602-3)
SSA2 [nucleoplasm]
(R-SCE-5082380)
SSA2 [nucleoplasm]
(R-SCE-6792605-3)
SSA2 [nucleoplasm]
(R-SCE-912480-3)
SSA2 [nucleoplasm]
(R-SCE-5082367-3)
SSA2 [nucleoplasm]
(R-SCE-5252082-3)
SSA2 [nucleoplasm]
(R-SCE-5252088-3)
SSA2 [nucleoplasm]
(R-SCE-5252009-3)
SSA2 [cytosol]
(R-SCE-5251948-3)
0.527
2
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