Reactome | RPL1B [cytosol]

RPL1B [cytosol]

Stable Identifier

R-SCE-9633206

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

fullName evidence="11"60S ribosomal protein L1-B, RL1B_YEAST

Locations in the PathwayBrowser

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Metabolism of RNA (Saccharomyces cerevisiae)

- Nonsense-Mediated Decay (NMD) (Saccharomyces cerevisiae)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Saccharomyces cerevisiae)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Saccharomyces cerevisiae)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPL1A,B [cytosol] (Saccharomyces cerevisiae)
        
        RPL1B [cytosol] (Saccharomyces cerevisiae)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPL1A,B [cytosol] (Saccharomyces cerevisiae)
        
        RPL1B [cytosol] (Saccharomyces cerevisiae)
    - SMG6 hydrolyzes mRNA with premature termination codon (Saccharomyces cerevisiae)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPL1A,B [cytosol] (Saccharomyces cerevisiae)
        
        RPL1B [cytosol] (Saccharomyces cerevisiae)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Saccharomyces cerevisiae)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Saccharomyces cerevisiae)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPL1A,B [cytosol] (Saccharomyces cerevisiae)
        
        RPL1B [cytosol] (Saccharomyces cerevisiae)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPL1A,B [cytosol] (Saccharomyces cerevisiae)
        
        RPL1B [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P0CX44 RPL1B

Gene Names

RPL1B, SSM1B, SSM2, YGL135W, G2834

Chain

initiator methionine:, chain:2-217

Reference Genes

BioGPS Gene:852742 RPL1B

BioGPS Gene:855881 RPL1B

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YGL135W RPL1B

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YPL220W RPL1B

Monarch:852742 RPL1B

Monarch:855881 RPL1B

NCBI Gene:852742 RPL1B

NCBI Gene:855881 RPL1B

Reference Transcript

Other Identifiers

1779233_s_at

7984_s_at

852742

855881

GO:0000054

GO:0000055

GO:0000470

GO:0002181

GO:0003674

GO:0003723

GO:0003735

GO:0005198

GO:0005575

GO:0005737

GO:0005829

GO:0005840

GO:0006364

GO:0006412

GO:0008150

GO:0015934

GO:0022625

GO:0042273

GO:0051169

GO:1990904

Participates

as a member of

RPL1A,B [cytosol] (Saccharomyces cerevisiae)

Inferred From

RPL10A [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_011380.3, NP_015104.1

PRO

P0CX44

PDB

5JCS

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