Reactome | PAC1 [cytosol]

PAC1 [cytosol]

Stable Identifier

R-SCE-976035

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

FBXW11, P39946

Locations in the PathwayBrowser

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Immune System (Saccharomyces cerevisiae)

- Adaptive Immune System (Saccharomyces cerevisiae)
  - Class I MHC mediated antigen processing & presentation (Saccharomyces cerevisiae)
    - Antigen processing: Ubiquitination & Proteasome degradation (Saccharomyces cerevisiae)
      - Release of E3 from polyubiquitinated substrate (Saccharomyces cerevisiae)
        
        E3 ligases in proteasomal degradation [cytosol] (Saccharomyces cerevisiae)
        
        SCF E3 ubiquitin ligase [cytosol] (Saccharomyces cerevisiae)
        
        F-box protein [cytosol] (Saccharomyces cerevisiae)
        
        PAC1 [cytosol] (Saccharomyces cerevisiae)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Saccharomyces cerevisiae)
        
        E3 ligases in proteasomal degradation [cytosol] (Saccharomyces cerevisiae)
        
        SCF E3 ubiquitin ligase [cytosol] (Saccharomyces cerevisiae)
        
        F-box protein [cytosol] (Saccharomyces cerevisiae)
        
        PAC1 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P39946

Gene Names

PAC1

Reference Genes

BioGPS Gene:854443 PAC1

ENSEMBL:YOR269W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YOR269W PAC1

KEGG Gene (Saccharomyces cerevisiae):YOR269W PAC1

Monarch:854443 PAC1

NCBI Gene:854443 PAC1

SGD:YOR269W

Reference Transcript

RefSeq:NM_001183688.1 PAC1

Other Identifiers

1778546_at

8290_at

854443

GO:0000132

GO:0000278

GO:0000776

GO:0000922

GO:0003674

GO:0005515

GO:0005575

GO:0005634

GO:0005635

GO:0005694

GO:0005737

GO:0005856

GO:0005874

GO:0005875

GO:0005881

GO:0007010

GO:0007017

GO:0007049

GO:0007097

GO:0008092

GO:0008150

GO:0012505

GO:0030473

GO:0031023

GO:0042802

GO:0047496

GO:0051010

GO:0051012

GO:0051301

GO:0070840

GO:1903033

GO:2000582

Participates

as a member of

F-box protein [cytosol] (Saccharomyces cerevisiae)

as a component of

CUL1:FBXW11:SKP1 [cytosol] (Saccharomyces cerevisiae)

Inferred From

FBXW11 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_014912.1

PRO

P39946

PDB

5VLJ, 5VH9, 7MGM

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14566 MCM6	1	MCM6 [nucleoplasm] (R-HSA-68553)	0.556	3

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