Reactome | KGD2 [mitochondrial matrix]

KGD2 [mitochondrial matrix]

Stable Identifier

R-SCE-9853485

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

mitochondrial matrix

Synonyms

LipoH2-K110-DLST, P19262

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P19262

Gene Names

KGD2

Reference Genes

BioGPS Gene:851726 KGD2

ENSEMBL:YDR148C

KEGG:sce:YDR148C KGD2

Monarch:851726 KGD2

NCBI Entrez Gene:851726 KGD2

SGD:YDR148C

UCSC:P19262 KGD2

Reference Transcript

RefSeq:NM_001180455.3 KGD2

Other Identifiers

851726

GO:0004149

GO:0005515

GO:0005575

GO:0005739

GO:0006099

GO:0006103

GO:0006520

GO:0009353

GO:0016740

GO:0016746

GO:0033512

GO:0042645

GO:0044281

GO:0045252

GO:0045333

GO:0055086

Participates

as an output of

DLST transfers succinyl to CoA (Saccharomyces cerevisiae)

as an input of

DLD dimer dehydrogenates dihydrolipoyl (Saccharomyces cerevisiae)

Other forms of this molecule

KGD2 [mitochondrial matrix]

Inferred From

LipoH2-K110-DLST [mitochondrial matrix] (Homo sapiens)

Modified Residues

Name

N6-lipoyl-L-lysine ((R)-N6-dihydrolipoyl-L-lysine residue) at 110 (in Homo sapiens)

Coordinate

110

Modification

(R)-N6-dihydrolipoyl-L-lysine residue

PsiMod Name

N6-lipoyl-L-lysine [MOD:00127]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-lipoyl-L-lysine.

Cross References

RefSeq

NP_010432.3

ENSEMBL

YDR148C_mRNA, YDR148C, YDR148C

PRO

P19262

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P20967	1	OGDH [mitochondrial matrix] (R-SCE-69981)	0.817	10
UniProt:P09624	1	DLD [mitochondrial matrix] (R-SCE-69978)	0.735	7
UniProt:P19955	1	YMR31 [mitochondrial inner membrane] (R-SCE-5368206)	0.643	5
UniProt:P19882 HSP60	7	HSP60 [mitochondrial matrix] (R-SCE-1252181) HSP60 [mitochondrial matrix] (R-SCE-1299448) HSP60 [mitochondrial inner membrane] (R-SCE-1267982) HSP60 precursor [mitochondrial inner membrane] (R-SCE-1267967) HSP60 precursor [mitochondrial intermembrane space] (R-SCE-1252158) HSP60 [cytosol] (R-SCE-1252153) HSP60 [mitochondrial matrix] (R-SCE-8986171)	0.527	2
UniProt:P11484	17	HSPA1L [cytosol] (R-SCE-3371410-4) HSPA2 [cytosol] (R-SCE-3371408-4) HSPA1A [cytosol] (R-SCE-6792602-4) HSPA6 [secretory granule lumen] (R-SCE-6801472-4) HSPA6 [extracellular region] (R-SCE-6806500-4) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-4) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) HSPA1A [extracellular region] (R-SCE-6805872-4) HSPA1A [nucleoplasm] (R-SCE-6792605-4) HSPA2 [nucleoplasm] (R-SCE-912480-4) HSPA1L [nucleoplasm] (R-SCE-5082367-4) HSPA14 [nucleoplasm] (R-SCE-5252082-4) HSPA6 [nucleoplasm] (R-SCE-5252088-4) HSPA13 [nucleoplasm] (R-SCE-5252009-4) HSPA14 [cytosol] (R-SCE-5251948-4) HSPA13 [cytosol] (R-SCE-5251981-4) HSPA6 [cytosol] (R-SCE-3371521-4)	0.527	2

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