Reactome | cig2 [nucleoplasm]

cig2 [nucleoplasm]

Stable Identifier

R-SPO-113832-3

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

nucleoplasm

Synonyms

CCND1, P36630

Locations in the PathwayBrowser

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Cell Cycle (Schizosaccharomyces pombe)

- Cell Cycle, Mitotic (Schizosaccharomyces pombe)
  - Mitotic G1 phase and G1/S transition (Schizosaccharomyces pombe)
    - G1 Phase (Schizosaccharomyces pombe)
      - Cyclin D associated events in G1 (Schizosaccharomyces pombe)
        
        CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Schizosaccharomyces pombe)
        
        CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Schizosaccharomyces pombe)
        
        CDK4:CCND [nucleoplasm] (Schizosaccharomyces pombe)
        
        CDK4:CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        cig2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        CDK6:CCND [nucleoplasm] (Schizosaccharomyces pombe)
        
        Cyclin D1:Cdk6 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        cig2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T172-CDK4:CCND [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T172-CDK4:CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        cig2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T177-CDK6:CCND [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T177-CDK6:CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        cig2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Drug-mediated inhibition of CDK4/CDK6 activity (Schizosaccharomyces pombe)
        
        CDK4 inhibitors bind CDK4 (Schizosaccharomyces pombe)
        
        p-T172-CDK4:CCND [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T172-CDK4:CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        cig2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T172-CDK4:CCND1:CDK4 inhibitors (CCND1) [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T172-CDK4:CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        cig2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        CDK6 inhibitors bind CDK6 (Schizosaccharomyces pombe)
        
        p-T177-CDK6:CCND [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T177-CDK6:CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        cig2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T177-CDK6:CCND1:CDK6 inhibitors (CCND1) [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T177-CDK6:CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        cig2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Schizosaccharomyces pombe)
        
        CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Schizosaccharomyces pombe)
        
        CDK4:CCND [nucleoplasm] (Schizosaccharomyces pombe)
        
        CDK4:CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        cig2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        CDK6:CCND [nucleoplasm] (Schizosaccharomyces pombe)
        
        Cyclin D1:Cdk6 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCND1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        cig2 [nucleoplasm] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:P36630

Gene Names

cig2

Reference Genes

BioGPS Gene:2543481 cig2

ENSEMBL:SPAPB2B4.03

GeneDB:SPAPB2B4.03

KEGG Gene (Schizosaccharomyces pombe):SPAPB2B4.03 cig2

Monarch:2543481 cig2

NCBI Gene:2543481 cig2

Reference Transcript

RefSeq:NM_001019319.2 cig2

Participates

as a member of

Homologues of CCND1 [nucleoplasm] (Schizosaccharomyces pombe)

Other forms of this molecule

cig2 [nucleoplasm]

phospho-cig2 [cytosol]

phospho-cig2 [nucleoplasm]

cig2 [cytosol]

cig2 [nucleoplasm]

cig2 [cytosol]

cig2 [nucleoplasm]

cig2 [cytosol]

cig2 [nucleoplasm]

Inferred From

CCND1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_593889.1

PRO

P36630

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