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What is Reactome ?
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cnp1 [nucleoplasm]
Stable Identifier
R-SPO-181914
Type
Protein [EntityWithAccessionedSequence]
Species
Schizosaccharomyces pombe
Compartment
nucleoplasm
Synonyms
HIST3H3, Q9Y812
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Cellular Senescence (Schizosaccharomyces pombe)
Oxidative Stress Induced Senescence (Schizosaccharomyces pombe)
KDM6B demethylates H3K27me3 on p16INK4A promoter (Schizosaccharomyces pombe)
CDKN2A Gene:Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
Histone H3 [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA Repair (Schizosaccharomyces pombe)
DNA Double-Strand Break Repair (Schizosaccharomyces pombe)
DNA Double Strand Break Response (Schizosaccharomyces pombe)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Schizosaccharomyces pombe)
ATM phosphorylates HERC2 (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:HERC2:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+ [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:p-T4827-HERC2:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+ [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
ATM phosphorylates MDC1 (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
ATM phosphorylates TP53BP1 at DNA DSBs (Schizosaccharomyces pombe)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:TP53BP1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
ATM phosphorylates WHSC1 (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
ATM recognizes H2AFX-Nucleosomes (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:p-T4827-HERC2:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+ [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
PPP5C dephosphorylates TP53BP1 (Schizosaccharomyces pombe)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:TP53BP1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
RNF8 and RNF168 ubiquitinate H2AFX (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
RNF8 binds phosphorylated MDC1 at DNA DSBs (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+ [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
TP53BP1 associates with H4K20Me2 at DNA DSBs (Schizosaccharomyces pombe)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:TP53BP1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
WHSC1 binds DNA DSBs (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
DNA Replication (Schizosaccharomyces pombe)
DNA Replication Pre-Initiation (Schizosaccharomyces pombe)
Assembly of the pre-replicative complex (Schizosaccharomyces pombe)
Assembly of the ORC complex at the origin of replication (Schizosaccharomyces pombe)
ORC1 binds to H4K20me2 (Schizosaccharomyces pombe)
H4K20Me2-nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
Histone H3 [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
ORC1:H4K20Me2-nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
H4K20Me2-nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
Histone H3 [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
Gene expression (Transcription) (Schizosaccharomyces pombe)
Epigenetic regulation of gene expression (Schizosaccharomyces pombe)
Negative epigenetic regulation of rRNA expression (Schizosaccharomyces pombe)
SIRT1 negatively regulates rRNA expression (Schizosaccharomyces pombe)
eNoSC deacetylates histone H3 (Schizosaccharomyces pombe)
Chromatin [nucleoplasm] (Schizosaccharomyces pombe)
Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
Histone H3 [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
eNoSC dimethylates histone H3 at lysine-9 (Schizosaccharomyces pombe)
Chromatin [nucleoplasm] (Schizosaccharomyces pombe)
Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
Histone H3 [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
Gene Silencing by RNA (Schizosaccharomyces pombe)
Transcriptional regulation by small RNAs (Schizosaccharomyces pombe)
AGO1,2:small RNA complexes interact with chromatin (Schizosaccharomyces pombe)
AGO1,2:miRNA:chromatin:RNA pol II [nucleoplasm] (Schizosaccharomyces pombe)
Chromatin [nucleoplasm] (Schizosaccharomyces pombe)
Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
Histone H3 [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
Chromatin [nucleoplasm] (Schizosaccharomyces pombe)
Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
Histone H3 [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
Signal Transduction (Schizosaccharomyces pombe)
Signaling by Nuclear Receptors (Schizosaccharomyces pombe)
ESR-mediated signaling (Schizosaccharomyces pombe)
Estrogen-dependent gene expression (Schizosaccharomyces pombe)
KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Schizosaccharomyces pombe)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Schizosaccharomyces pombe)
HIST1H2AC nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
Histone H3 [nucleoplasm] (Schizosaccharomyces pombe)
cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
External Reference Information
External Reference
UniProt:Q9Y812
Gene Names
cnp1
Reference Genes
BioGPS Gene:2539658 cnp1
ENSEMBL:SPBC1105.17
KEGG:spo:2539658 cnp1
Monarch:2539658 cnp1
NCBI Gene:2539658 cnp1
PomBase:SPBC1105.17
UCSC:Q9Y812 cnp1
Reference Transcript
RefSeq:NM_001022392.2 cnp1
Participates
as a candidate of
Histone H3 [nucleoplasm] (Schizosaccharomyces pombe)
as a member of
Histone H3 [nucleoplasm] (Schizosaccharomyces pombe)
as a component of
Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
H2AFX-Nucleosome [nucleoplasm] (Schizosaccharomyces pombe)
Other forms of this molecule
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [cytosol]
cnp1 [cytosol]
cnp1 [cytosol]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
phospho-cnp1 [nucleoplasm]
phospho-cnp1 [nucleoplasm]
phospho-cnp1 [nucleoplasm]
phospho-cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
cnp1 [nucleoplasm]
Inferred From
HIST1H3A [nucleoplasm]
(Homo sapiens)
HIST3H3 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_596473.1
PRO
Q9Y812
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y738 MIS12
0.528
3
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