Reactome | rad25 [cytosol]

rad25 [cytosol]

Stable Identifier

R-SPO-194368-2

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

cytosol

Synonyms

YWHAE, P42657

Locations in the PathwayBrowser

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Cell Cycle (Schizosaccharomyces pombe)

- Cell Cycle Checkpoints (Schizosaccharomyces pombe)
  - G2/M Checkpoints (Schizosaccharomyces pombe)
    - G2/M DNA damage checkpoint (Schizosaccharomyces pombe)
      - Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Schizosaccharomyces pombe)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Schizosaccharomyces pombe)
        
        YWHAE dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of YWHAE [cytosol] (Schizosaccharomyces pombe)
        
        rad25 [cytosol] (Schizosaccharomyces pombe)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Schizosaccharomyces pombe)
        
        YWHAE dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of YWHAE [cytosol] (Schizosaccharomyces pombe)
        
        rad25 [cytosol] (Schizosaccharomyces pombe)

Gene expression (Transcription) (Schizosaccharomyces pombe)

- RNA Polymerase II Transcription (Schizosaccharomyces pombe)
  - Generic Transcription Pathway (Schizosaccharomyces pombe)
    - Transcriptional Regulation by TP53 (Schizosaccharomyces pombe)
      - TP53 Regulates Metabolic Genes (Schizosaccharomyces pombe)
        
        p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Schizosaccharomyces pombe)
        
        YWHAE dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of YWHAE [cytosol] (Schizosaccharomyces pombe)
        
        rad25 [cytosol] (Schizosaccharomyces pombe)
        
        p-S939,T1462-TSC2:14-3-3 dimer [cytosol] (Schizosaccharomyces pombe)
        
        YWHAE dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of YWHAE [cytosol] (Schizosaccharomyces pombe)
        
        rad25 [cytosol] (Schizosaccharomyces pombe)

Signal Transduction (Schizosaccharomyces pombe)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Schizosaccharomyces pombe)
  - Signaling by Rho GTPases (Schizosaccharomyces pombe)
    - RHO GTPase Effectors (Schizosaccharomyces pombe)
      - RHO GTPases activate PKNs (Schizosaccharomyces pombe)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Schizosaccharomyces pombe)
        
        YWHAE dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of YWHAE [cytosol] (Schizosaccharomyces pombe)
        
        rad25 [cytosol] (Schizosaccharomyces pombe)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Schizosaccharomyces pombe)
        
        YWHAE dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of YWHAE [cytosol] (Schizosaccharomyces pombe)
        
        rad25 [cytosol] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:P42657

Gene Names

rad25

Reference Genes

BioGPS Gene:2542252 rad25

ENSEMBL:SPAC17A2.13c

KEGG:spo:2542252 rad25

Monarch:2542252 rad25

NCBI Gene:2542252 rad25

PomBase:SPAC17A2.13c

UCSC:P42657 rad25

Reference Transcript

RefSeq:NM_001019670.2 rad25

Participates

as a member of

Homologues of YWHAE [cytosol] (Schizosaccharomyces pombe)

Inferred From

YWHAE [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_594247.1

PRO

P42657

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