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MLH1:PMS2 [nucleoplasm]
Stable Identifier
R-SPO-5357522
Type
Complex
Species
Schizosaccharomyces pombe
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Schizosaccharomyces pombe)
Mismatch Repair (Schizosaccharomyces pombe)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Schizosaccharomyces pombe)
EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Schizosaccharomyces pombe)
EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2 [nucleoplasm] (Schizosaccharomyces pombe)
EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Schizosaccharomyces pombe)
EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2 [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2 [nucleoplasm] (Schizosaccharomyces pombe)
Formation of MSH1:PMS2 Complex (Schizosaccharomyces pombe)
MLH1:PMS2 [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Schizosaccharomyces pombe)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2 [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2 [nucleoplasm] (Schizosaccharomyces pombe)
MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Schizosaccharomyces pombe)
MLH1:PMS2 [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2 [nucleoplasm] (Schizosaccharomyces pombe)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
mlh1 [nucleoplasm]
(Schizosaccharomyces pombe)
pms1 [nucleoplasm]
(Schizosaccharomyces pombe)
Participates
as a component of
EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Schizosaccharomyces pombe)
as an input of
MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Schizosaccharomyces pombe)
as an output of
Formation of MSH1:PMS2 Complex (Schizosaccharomyces pombe)
Inferred From
MLH1:PMS2 [nucleoplasm]
(Homo sapiens)
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