Reactome | MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm]

MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm]

Stable Identifier

R-SPO-5358528

Type

Complex

Species

Schizosaccharomyces pombe

Compartment

nucleoplasm

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

DNA containing 1-2 base mismatch and single-strand incision [nucleoplasm]
MLH1:PMS2 [nucleoplasm] (Schizosaccharomyces pombe)
MSH2:MSH6:ATP [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)

Participates

as an input of

EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Schizosaccharomyces pombe)

as an output of

MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Schizosaccharomyces pombe)

Inferred From

MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Homo sapiens)

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