Reactome | IQGAP1 [cytosol]

IQGAP1 [cytosol]

Stable Identifier

R-SPO-5626371-2

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

cytosol

Synonyms

Q10201

Locations in the PathwayBrowser

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Signal Transduction (Schizosaccharomyces pombe)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Schizosaccharomyces pombe)
  - Signaling by Rho GTPases (Schizosaccharomyces pombe)
    - RHO GTPase Effectors (Schizosaccharomyces pombe)
      - RHO GTPases activate IQGAPs (Schizosaccharomyces pombe)
        
        GTP-bound RAC1 and CDC42 bind IQGAPs (Schizosaccharomyces pombe)
        
        IQGAP [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Schizosaccharomyces pombe)
        
        IQGAP [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 binds CLIP1 and microtubules (Schizosaccharomyces pombe)
        
        RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Schizosaccharomyces pombe)
        
        RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAPs bind F-actin, which is inhibited by calmodulin (Schizosaccharomyces pombe)
        
        RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Schizosaccharomyces pombe)
        
        RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Schizosaccharomyces pombe)
        
        IQGAP [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Schizosaccharomyces pombe)
        
        IQGAP [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
    - RHO GTPase cycle (Schizosaccharomyces pombe)
      - RHOA GTPase cycle (Schizosaccharomyces pombe)
        
        RHOA binds effectors at the plasma membrane (Schizosaccharomyces pombe)
        
        RHOA plasma membrane effectors [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Schizosaccharomyces pombe)
        
        RHOA plasma membrane effectors [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
      - RHOQ GTPase cycle (Schizosaccharomyces pombe)
        
        RHOQ binds effectors at the plasma membrane (Schizosaccharomyces pombe)
        
        RHOQ effectors [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        RHOQ:GTP:RHOQ effectors [plasma membrane] (Schizosaccharomyces pombe)
        
        RHOQ effectors [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
      - RHOU GTPase cycle (Schizosaccharomyces pombe)
        
        RHOU binds effectors at the plasma membrane (Schizosaccharomyces pombe)
        
        RHOU effectors [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        RHOU:GTP:RHOU effectors [plasma membrane] (Schizosaccharomyces pombe)
        
        RHOU effectors [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
      - RHOV GTPase cycle (Schizosaccharomyces pombe)
        
        RHOV binds effectors at the plasma membrane (Schizosaccharomyces pombe)
        
        RHOV effectors [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        RHOV:GTP:RHOV effectors [plasma membrane] (Schizosaccharomyces pombe)
        
        RHOV effectors [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 dimer [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)
        
        IQGAP1 [cytosol] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:Q10201

Reference Genes

BioGPS Gene:2540178

ENSEMBL:SPBC17D1.07c

GeneDB:SPBC17D1.07c

KEGG Gene (Schizosaccharomyces pombe):SPBC17D1.07c

Monarch:2540178

NCBI Gene:2540178

Reference Transcript

RefSeq:NM_001022310.2

Participates

as a member of

Homologues of IQGAP1 [cytosol] (Schizosaccharomyces pombe)

Other forms of this molecule

IQGAP1 [plasma membrane]

IQGAP1 [secretory granule membrane]

IQGAP3 [cytosol]

Inferred From

IQGAP1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_596389.2

PRO

Q10201

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