Reactome | rps1601 [cytosol]

rps1601 [cytosol]

Stable Identifier

R-SPO-72337

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

cytosol

Synonyms

RPS16, P0CT64

Locations in the PathwayBrowser

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Metabolism of RNA (Schizosaccharomyces pombe)

- Nonsense-Mediated Decay (NMD) (Schizosaccharomyces pombe)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Schizosaccharomyces pombe)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Schizosaccharomyces pombe)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        40S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPS16 [cytosol] (Schizosaccharomyces pombe)
        
        rps1601 [cytosol] (Schizosaccharomyces pombe)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        40S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPS16 [cytosol] (Schizosaccharomyces pombe)
        
        rps1601 [cytosol] (Schizosaccharomyces pombe)
    - SMG6 hydrolyzes mRNA with premature termination codon (Schizosaccharomyces pombe)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        40S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPS16 [cytosol] (Schizosaccharomyces pombe)
        
        rps1601 [cytosol] (Schizosaccharomyces pombe)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Schizosaccharomyces pombe)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Schizosaccharomyces pombe)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        40S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPS16 [cytosol] (Schizosaccharomyces pombe)
        
        rps1601 [cytosol] (Schizosaccharomyces pombe)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        40S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPS16 [cytosol] (Schizosaccharomyces pombe)
        
        rps1601 [cytosol] (Schizosaccharomyces pombe)
- rRNA processing (Schizosaccharomyces pombe)
  - rRNA processing in the nucleus and cytosol (Schizosaccharomyces pombe)
    - Major pathway of rRNA processing in the nucleolus and cytosol (Schizosaccharomyces pombe)
      - 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Schizosaccharomyces pombe)
        
        40S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPS16 [cytosol] (Schizosaccharomyces pombe)
        
        rps1601 [cytosol] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:P0CT64

Gene Names

rps1601

Reference Genes

BioGPS Gene:2540812 rps1601

BioGPS Gene:2543559 rps1601

ENSEMBL:SPBC18H10.14

KEGG:spo:2540812 rps1601

KEGG:spo:2543559 rps1601

Monarch:2540812 rps1601

Monarch:2543559 rps1601

NCBI Gene:2540812 rps1601

NCBI Gene:2543559 rps1601

PomBase:SPBC18H10.14

UCSC:P0CT64 rps1601

Reference Transcript

Participates

as a member of

Homologues of RPS16 [cytosol] (Schizosaccharomyces pombe)

Other forms of this molecule

rps1601 [nucleoplasm]

Inferred From

RPS16 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_593452.1, NP_595738.1

PRO

P0CT64

PDB

9AXV, 9AXT

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