Reactome | rpl39 [cytosol]

rpl39 [cytosol]

Stable Identifier

R-SPO-72472

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

cytosol

Synonyms

RPL39, P05767

Locations in the PathwayBrowser

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Metabolism of RNA (Schizosaccharomyces pombe)

- Nonsense-Mediated Decay (NMD) (Schizosaccharomyces pombe)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Schizosaccharomyces pombe)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Schizosaccharomyces pombe)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        rpl39 [cytosol] (Schizosaccharomyces pombe)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        rpl39 [cytosol] (Schizosaccharomyces pombe)
    - SMG6 hydrolyzes mRNA with premature termination codon (Schizosaccharomyces pombe)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        rpl39 [cytosol] (Schizosaccharomyces pombe)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Schizosaccharomyces pombe)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Schizosaccharomyces pombe)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        rpl39 [cytosol] (Schizosaccharomyces pombe)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        rpl39 [cytosol] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:P05767

Gene Names

rpl39

Reference Genes

ENSEMBL:SPCC663.04

GeneDB:SPCC663.04

Reference Transcript

RefSeq:NM_001023256.2 rpl39

Participates

as a component of

Other forms of this molecule

rpl39 [cytosol]

Inferred From

RPL39,RPL39L [cytosol] (Homo sapiens)

RPL39 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_588266.1

PRO

P05767

PDB

8EUG, 8ESR, 8ETC, 8ESQ, 8EUI

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