Reactome | end3 [cytosol]

end3 [cytosol]

Stable Identifier

R-SPO-8862265-5

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

cytosol

Synonyms

REPS1, Q9USZ7

Locations in the PathwayBrowser

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Vesicle-mediated transport (Schizosaccharomyces pombe)

- Membrane Trafficking (Schizosaccharomyces pombe)
  - Clathrin-mediated endocytosis (Schizosaccharomyces pombe)
    - AAK1 phosphorylates AP-2 mu subunit at T156 (Schizosaccharomyces pombe)
      - PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Schizosaccharomyces pombe)
        
        PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Schizosaccharomyces pombe)
        
        Homologues of REPS1 [cytosol] (Schizosaccharomyces pombe)
        
        end3 [cytosol] (Schizosaccharomyces pombe)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Schizosaccharomyces pombe)
        
        Homologues of REPS1 [cytosol] (Schizosaccharomyces pombe)
        
        end3 [cytosol] (Schizosaccharomyces pombe)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Schizosaccharomyces pombe)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
        
        Homologues of REPS1 [cytosol] (Schizosaccharomyces pombe)
        
        end3 [cytosol] (Schizosaccharomyces pombe)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
        
        Homologues of REPS1 [cytosol] (Schizosaccharomyces pombe)
        
        end3 [cytosol] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:Q9USZ7

Gene Names

end3

Reference Genes

BioGPS Gene:2539902 end3

ENSEMBL:SPBC11G11.02c

GeneDB:SPBC11G11.02c

KEGG Gene (Schizosaccharomyces pombe):SPBC11G11.02c end3

Monarch:2539902 end3

NCBI Gene:2539902 end3

Reference Transcript

RefSeq:NM_001021618.2 end3

Participates

as a member of

Homologues of REPS1 [cytosol] (Schizosaccharomyces pombe)

Other forms of this molecule

end3 [cytosol]

Inferred From

REPS1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_595720.1

PRO

Q9USZ7

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