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BUB1B [cytosol]
Stable Identifier
R-SSC-141436
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
BUB1B, I3LEQ9
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle Checkpoints (Sus scrofa)
Mitotic Spindle Checkpoint (Sus scrofa)
Amplification of signal from the kinetochores (Sus scrofa)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Sus scrofa)
MAD2 associates with the Mad1 kinetochore complex (Sus scrofa)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Sus scrofa)
Mad1:kinetochore complex [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Mad1:kinetochore complex [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
MAD2 converted to an inhibitory state via interaction with Mad1 (Sus scrofa)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Sus scrofa)
Mad1:kinetochore complex [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Mad1 binds kinetochore (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Mad1:kinetochore complex [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Release of activated MAD2 from kinetochores (Sus scrofa)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Sus scrofa)
Mad1:kinetochore complex [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Mad1:kinetochore complex [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Sus scrofa)
Inactivation of APC/C via direct inhibition of the APC/C complex (Sus scrofa)
Binding of the MCC complex to the APC/C complex (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Formation of the MCC complex (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
M Phase (Sus scrofa)
Mitotic Metaphase and Anaphase (Sus scrofa)
Mitotic Anaphase (Sus scrofa)
Separation of Sister Chromatids (Sus scrofa)
ESPL1 (Separase) cleaves centromeric cohesin (Sus scrofa)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Separation of sister chromatids (Sus scrofa)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Mitotic Prometaphase (Sus scrofa)
EML4 and NUDC in mitotic spindle formation (Sus scrofa)
EML4 recruits NUDC to mitotic spindle (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Kinetochore capture of astral microtubules (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Resolution of Sister Chromatid Cohesion (Sus scrofa)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Sus scrofa)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Kinetochore assembly (Sus scrofa)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
PP2A-B56 dephosphorylates centromeric cohesin (Sus scrofa)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Phosphorylation of cohesin by PLK1 at centromeres (Sus scrofa)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Regulation of mitotic cell cycle (Sus scrofa)
APC/C-mediated degradation of cell cycle proteins (Sus scrofa)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Sus scrofa)
APC/C:Cdc20 mediated degradation of mitotic proteins (Sus scrofa)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Sus scrofa)
APC-Cdc20 mediated degradation of Nek2A (Sus scrofa)
Degradation of multiubiquitinated Nek2A (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Multiubiquitinated Nek2A [cytosol] (Sus scrofa)
Nek2A:MCC:APC/C complex [cytosol] (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Multiubiquitination of Nek2A (Sus scrofa)
Multiubiquitinated Nek2A [cytosol] (Sus scrofa)
Nek2A:MCC:APC/C complex [cytosol] (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Nek2A:MCC:APC/C complex [cytosol] (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Sus scrofa)
Association of Cyclin A with the APC/C (Sus scrofa)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Degradation multiubiquitinated Cyclin A (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Sus scrofa)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Sus scrofa)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Sus scrofa)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
hBUBR1:hBUB3:MAD2* complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Regulation of APC/C activators between G1/S and early anaphase (Sus scrofa)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Sus scrofa)
Inactivation of APC/C via direct inhibition of the APC/C complex (Sus scrofa)
Binding of the MCC complex to the APC/C complex (Sus scrofa)
MCC:APC/C complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Formation of the MCC complex (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase Effectors (Sus scrofa)
RHO GTPases Activate Formins (Sus scrofa)
AURKB phosphorylates DIAPH2-2 at kinetochores (Sus scrofa)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
CDC42:GTP recruits DIAPH2-2 to kinetochores (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
Microtubule-bound kinetochore [cytosol] (Sus scrofa)
Kinetochore [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
BUB1B [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:I3LEQ9
Gene Names
BUB1B
Reference Genes
ENSEMBL:ENSSSCG00000004782.5
Other Identifiers
102164975
GO:0000278
GO:0000776
GO:0000940
GO:0003824
GO:0004672
GO:0005524
GO:0005634
GO:0005694
GO:0005737
GO:0005819
GO:0005829
GO:0005856
GO:0006468
GO:0007059
GO:0007091
GO:0007094
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0033597
GO:0036211
GO:0043226
GO:0048471
GO:0071459
GO:0140014
GO:0140096
Ssc.7190.1.S1_at
Participates
as a component of
hBUBR1:hBUB3:MAD2* complex [cytosol] (Sus scrofa)
Mitotic checkpoint complex [cytosol] (Sus scrofa)
as an input of
Formation of the MCC complex (Sus scrofa)
Inferred From
BUB1B [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000156970
Ensembl
ENSSSCP00000022548
,
ENSSSCG00000004782
,
ENSSSCT00000031444
VGNC
103039
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