Reactome | NDUFB5 [mitochondrial inner membrane]

NDUFB5 [mitochondrial inner membrane]

Stable Identifier

R-SSC-163944

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

mitochondrial inner membrane

Synonyms

NDUFB5, F1SGC6

Locations in the PathwayBrowser

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Metabolism (Sus scrofa)

- Aerobic respiration and respiratory electron transport (Sus scrofa)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Sus scrofa)
    - Respiratory electron transport (Sus scrofa)
      - Complex I biogenesis (Sus scrofa)
        
        Intermediate 1 binds HP subcomplex to form Intermediate 2 (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)
        
        ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)
        
        Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)
        
        980kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)
        
        The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)
        
        The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Sus scrofa)
        
        980kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)
        
        Complex I [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Sus scrofa)
        
        Complex I [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB5 [mitochondrial inner membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SGC6

Gene Names

NDUFB5

Reference Genes

BioGPS Gene:100523751 NDUFB5

ENSEMBL:ENSSSCG00000011764.5

ENSEMBL:ENSSSCG00005010015.1 NDUFB5

KEGG Gene (Sus scrofa):100523751 NDUFB5

Monarch:100523751 NDUFB5

NCBI Gene:100523751 NDUFB5

Reference Transcript

RefSeq:XM_003132546.2 NDUFB5

Other Identifiers

100523751

GO:0005634

GO:0005654

GO:0005739

GO:0005743

GO:0005747

GO:0007005

GO:0016020

GO:0032981

GO:0043226

GO:0065003

Ssc.1155.1.S1_at

Ssc.2003.1.A1_at

Participates

as a component of

HP subcomplex [mitochondrial inner membrane] (Sus scrofa)

Inferred From

NDUFB5 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

XP_003132594.1

OpenTargets

ENSG00000136521

Ensembl

ENSSSCP00000012534, ENSSSCG00000011764, ENSSSCT00000012875

VGNC

104006

PDB

7W4C, 7W2R, 7VXS, 7W2U, 7VY9, 7VZW, 7V2D, 7V2F, 7W2Y, 7W4G, 7W1O, 7V2K, 7W4M, 7VBP, 7W4K, 7VYG, 7VYI, 7V31, 7V2R, 7W1U, 7V33, 7W1Z, 5GPN, 7VZ8, 7W0R, 7W2K, 7V3M, 7VY1, 7W0Y, 5GUP, 7W4E, 7V2C, 7W4D, 7V2E, 7VBL, 7W4J, 7VZV, 7V2H, 7W4F, 7W32, 7W00, 7VC0, 7W4N, 7W35, 7W1P, 7VYE, 7W4L, 7W20, 7V30, 7W1T, 7VWL, 7W4Q, 7V32, 7W1V, 7VYS, 7W0H, 7W31, 7W2L

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