Reactome | GNA13 [plasma membrane]

GNA13 [plasma membrane]

Stable Identifier

R-SSC-167451

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

GNA13, A0A287A853

Locations in the PathwayBrowser

Expand all

Hemostasis (Sus scrofa)

- Platelet activation, signaling and aggregation (Sus scrofa)
  - Signal amplification (Sus scrofa)
    - Thromboxane signalling through TP receptor (Sus scrofa)
      - Activated TP receptor binds G-protein G13 (Sus scrofa)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein alpha (13):GDP [plasma membrane] (Sus scrofa)
        
        GNA13 [plasma membrane] (Sus scrofa)
        
        TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein alpha (13):GDP [plasma membrane] (Sus scrofa)
        
        GNA13 [plasma membrane] (Sus scrofa)
      - Dissociation of the TP:G13 complex (Sus scrofa)
        
        G-protein alpha (13):GTP [plasma membrane] (Sus scrofa)
        
        GNA13 [plasma membrane] (Sus scrofa)
        
        TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Sus scrofa)
        
        G-protein alpha (13):GTP [plasma membrane] (Sus scrofa)
        
        GNA13 [plasma membrane] (Sus scrofa)
      - G13 activation by TP receptor (Sus scrofa)
        
        TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Sus scrofa)
        
        G-protein alpha (13):GTP [plasma membrane] (Sus scrofa)
        
        GNA13 [plasma membrane] (Sus scrofa)
        
        TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein alpha (13):GDP [plasma membrane] (Sus scrofa)
        
        GNA13 [plasma membrane] (Sus scrofa)
  - Thrombin signalling through proteinase activated receptors (PARs) (Sus scrofa)
    - Thrombin-activated PARs activate G12/13 (Sus scrofa)
      - Thrombin activated PAR:G12/13 (active) [plasma membrane] (Sus scrofa)
        
        G-protein G12/G13 (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Sus scrofa)
        
        G-protein alpha (13):GTP [plasma membrane] (Sus scrofa)
        
        GNA13 [plasma membrane] (Sus scrofa)
      - Thrombin activated PAR:G12/13 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein G12/G13 (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein alpha (13):GDP [plasma membrane] (Sus scrofa)
        
        GNA13 [plasma membrane] (Sus scrofa)
    - Thrombin-activated PARs:G12/13 (active) dissociate (Sus scrofa)
      - G-protein alpha (12/13):GTP [plasma membrane] (Sus scrofa)
        
        G-protein alpha (13):GTP [plasma membrane] (Sus scrofa)
        
        GNA13 [plasma membrane] (Sus scrofa)
      - Thrombin activated PAR:G12/13 (active) [plasma membrane] (Sus scrofa)
        
        G-protein G12/G13 (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Sus scrofa)
        
        G-protein alpha (13):GTP [plasma membrane] (Sus scrofa)
        
        GNA13 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287A853

Gene Names

GNA13

Reference Genes

BioGPS Gene:100522824 GNA13

ENSEMBL:ENSSSCG00000039336.2

KEGG Gene (Sus scrofa):100522824 GNA13

Monarch:100522824 GNA13

NCBI Gene:100522824 GNA13

Reference Transcript

RefSeq:XM_003357998.3 GNA13

Other Identifiers

100522824

GO:0000166

GO:0001525

GO:0001569

GO:0001664

GO:0001701

GO:0003013

GO:0003824

GO:0003924

GO:0005525

GO:0005634

GO:0005737

GO:0005829

GO:0005834

GO:0005886

GO:0007165

GO:0007186

GO:0007188

GO:0007189

GO:0007266

GO:0008217

GO:0008360

GO:0010762

GO:0016020

GO:0016787

GO:0019001

GO:0023052

GO:0030154

GO:0030168

GO:0031526

GO:0031683

GO:0031752

GO:0035556

GO:0042060

GO:0043226

GO:0048856

GO:0048870

Participates

as a candidate of

CDC42 GEFs [cytosol] (Sus scrofa)

as a member of

RAC1 GEFs [cytosol] (Sus scrofa)

as a component of

Inferred From

GNA13 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_003358046.1

OpenTargets

ENSG00000120063

Ensembl

ENSSSCG00000039336, ENSSSCP00000040165, ENSSSCT00000057079

VGNC

98997

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