Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
EIF2AK2 [cytosol]
Stable Identifier
R-SSC-168699
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
A0A287BKF1
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Interferon Signaling (Sus scrofa)
Antiviral mechanism by IFN-stimulated genes (Sus scrofa)
ISG15 antiviral mechanism (Sus scrofa)
ISGylation of host proteins (Sus scrofa)
ISG15 targets [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
ISGylated host proteins [cytosol] (Sus scrofa)
ISG15 targets [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Sus scrofa)
ISG15 targets [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
ISGylated host proteins [cytosol] (Sus scrofa)
ISG15 targets [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
PKR-mediated signaling (Sus scrofa)
ADAR1 binds PKR (Sus scrofa)
ADAR1 dimer:EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
DNAJC3 binds PKR (Sus scrofa)
DNAJC3:EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
DUS2 binds PKR (Sus scrofa)
DUS2:EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
FA core complex:HSP70s binds PKR (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
FA Core Complex:HSP70s:EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
Heparin binds PKR (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 dimer:heparin [cytosol] (Sus scrofa)
EIF2AK2 dimer [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
IKK complex is activated by PKR (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2:CHUK:IKBKB:IKBKG [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
ILF3 binds PKR (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
ILF3:EIF2AK2 dimer [cytosol] (Sus scrofa)
EIF2AK2 dimer [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
ISGylation of PKR (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
NCK1 binds PKR (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2:NCK1 [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
NPM binds PKR (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
NPM1:EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
PKR binds activating host RNA (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 dimer:Host RNA activators [cytosol] (Sus scrofa)
EIF2AK2 dimer [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
PKR inhibitors bind PKR (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2:PKR inhibitors [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
SPHK1 binds PKR (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2:p-SPHK1 [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
STAT1,STAT3 binds PKR (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
STAT1,STAT3:EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
p-PRKRA dimer binds PKR (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
p-TARBP2 binds PKR (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
p-TARBP2:EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A287BKF1
Reference Genes
ENSEMBL:ENSSSCG00000008496.6
Other Identifiers
397588
GO:0001819
GO:0002376
GO:0003723
GO:0003725
GO:0003824
GO:0004672
GO:0004694
GO:0005737
GO:0005829
GO:0006412
GO:0009615
GO:0012501
GO:0016301
GO:0016740
GO:0017148
GO:0023052
GO:0030154
GO:0030968
GO:0032722
GO:0032874
GO:0033689
GO:0034198
GO:0035455
GO:0036211
GO:0042802
GO:0043066
GO:0043410
GO:0045071
GO:0045182
GO:0048471
GO:0048856
GO:0051607
GO:0065003
GO:0098542
GO:0140096
GO:0140374
GO:1900225
GO:1901224
GO:1901532
GO:1902033
GO:1902036
Ssc.6430.1.A1_at
Ssc.7274.1.A1_at
Participates
as a member of
ISG15 targets [cytosol] (Sus scrofa)
as an input of
ADAR1 binds PKR (Sus scrofa)
DUS2 binds PKR (Sus scrofa)
SPHK1 binds PKR (Sus scrofa)
DNAJC3 binds PKR (Sus scrofa)
Heparin binds PKR (Sus scrofa)
PKR binds activating host RNA (Sus scrofa)
STAT1,STAT3 binds PKR (Sus scrofa)
NCK1 binds PKR (Sus scrofa)
ISGylation of PKR (Sus scrofa)
ILF3 binds PKR (Sus scrofa)
NPM binds PKR (Sus scrofa)
p-PRKRA dimer binds PKR (Sus scrofa)
PKR inhibitors bind PKR (Sus scrofa)
p-TARBP2 binds PKR (Sus scrofa)
FA core complex:HSP70s binds PKR (Sus scrofa)
IKK complex is activated by PKR (Sus scrofa)
as a component of
p-TARBP2:EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2:PKR inhibitors [cytosol] (Sus scrofa)
ADAR1 dimer:EIF2AK2 [cytosol] (Sus scrofa)
DNAJC3:EIF2AK2 [cytosol] (Sus scrofa)
DUS2:EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2:NCK1 [cytosol] (Sus scrofa)
EIF2AK2:p-SPHK1 [cytosol] (Sus scrofa)
STAT1,STAT3:EIF2AK2 [cytosol] (Sus scrofa)
NPM1:EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2 dimer [cytosol] (Sus scrofa)
FA Core Complex:HSP70s:EIF2AK2 [cytosol] (Sus scrofa)
EIF2AK2:CHUK:IKBKB:IKBKG [cytosol] (Sus scrofa)
Other forms of this molecule
phospho-p-EIF2AK2 [nucleoplasm]
SUMO-EIF2AK2 [cytosol]
ISG15-EIF2AK2 [cytosol]
phospho-p-EIF2AK2 [cytosol]
Inferred From
EIF2AK2 [cytosol]
(Homo sapiens)
Cross References
Ensembl
ENSSSCG00000008496
,
ENSSSCT00000034217
,
ENSSSCP00000057073
VGNC
87607
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text