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TGFBR2 [plasma membrane]
Stable Identifier
R-SSC-170842
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
plasma membrane
Synonyms
A0A5G2RC56
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
Signaling by TGFB family members (Sus scrofa)
Signaling by TGF-beta Receptor Complex (Sus scrofa)
TGF-beta receptor signaling activates SMADs (Sus scrofa)
Activated type I receptor phosphorylates SMAD2/3 directly (Sus scrofa)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
CBL binds TGFBR2 (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFBR2:CBL [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
CBL neddylates TGFBR2 (Sus scrofa)
TGFBR2:CBL [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
Dimeric TGF-beta-1 binds to the receptor (Sus scrofa)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
Downregulation of TGF-beta receptor signaling (Sus scrofa)
BAMBI interferes with the interaction of type I receptor with type II receptor (Sus scrofa)
TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
Degradation of TGF-beta receptor complex (Sus scrofa)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Sus scrofa)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Sus scrofa)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Sus scrofa)
TGFB1: p-TGFBR: STRAP: SMAD7 [plasma membrane] (Sus scrofa)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
Phosphorylated SMAD2/3 dissociates from TGFBR (Sus scrofa)
TGFB1:p-TGFBR:ZFYVE9 [early endosome membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFBR2 phosphorylates TGFBR1 (Sus scrofa)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFBR2 recruits TGFBR1 (Sus scrofa)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Sus scrofa)
Disassembly of tight junctions (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
SMURF1 binds phosphorylated PARD6A (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
SMURF1 ubiquitinates RHOA (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Sus scrofa)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
TGFBR2 [plasma membrane] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A5G2RC56
Reference Genes
ENSEMBL:ENSSSCG00000011226.6
Other Identifiers
100038019
GO:0000166
GO:0001569
GO:0001570
GO:0001701
GO:0001837
GO:0001947
GO:0002053
GO:0002088
GO:0002376
GO:0002651
GO:0002663
GO:0002666
GO:0003148
GO:0003149
GO:0003151
GO:0003180
GO:0003181
GO:0003186
GO:0003214
GO:0003274
GO:0003417
GO:0003430
GO:0003824
GO:0004672
GO:0004674
GO:0004675
GO:0005024
GO:0005026
GO:0005524
GO:0005539
GO:0005886
GO:0005901
GO:0006468
GO:0006915
GO:0007155
GO:0007178
GO:0007179
GO:0007219
GO:0007224
GO:0007369
GO:0007420
GO:0007507
GO:0009410
GO:0009897
GO:0010468
GO:0010634
GO:0010718
GO:0012501
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0019209
GO:0023052
GO:0030154
GO:0030324
GO:0034713
GO:0035162
GO:0035909
GO:0036211
GO:0042127
GO:0043235
GO:0045121
GO:0045766
GO:0046332
GO:0046872
GO:0048701
GO:0048844
GO:0048856
GO:0048870
GO:0050431
GO:0051138
GO:0051216
GO:0060021
GO:0060089
GO:0060391
GO:0060395
GO:0060412
GO:0060425
GO:0060433
GO:0060434
GO:0060439
GO:0060440
GO:0060443
GO:0060463
GO:0061520
GO:0062009
GO:0070021
GO:0070723
GO:0072091
GO:0098772
GO:0140096
GO:1905007
GO:1905317
GO:1990086
GO:1990428
GO:2000379
GO:2000563
GO:2000736
Ssc.19140.1.A1_at
Participates
as an input of
CBL binds TGFBR2 (Sus scrofa)
Dimeric TGF-beta-1 binds to the receptor (Sus scrofa)
as a component of
TGFBR2:CBL [plasma membrane] (Sus scrofa)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Sus scrofa)
TGFBR2 homodimer [plasma membrane] (Sus scrofa)
Other forms of this molecule
NEDD8-K556,K567-TGFBR2 [plasma membrane]
Inferred From
TGFBR2 [plasma membrane]
(Homo sapiens)
Cross References
Ensembl
ENSSSCP00000071792
,
ENSSSCG00000011226
,
ENSSSCT00000067593
VGNC
93931
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