Reactome | p-2S-SMAD2,3 [nucleoplasm]

p-2S-SMAD2,3 [nucleoplasm]

Stable Identifier

R-SSC-177105

Type

Set [DefinedSet]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

Phospho-R-SMAD

Locations in the PathwayBrowser

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Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - Generic Transcription Pathway (Sus scrofa)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Sus scrofa)
      - Downregulation of SMAD2/3:SMAD4 transcriptional activity (Sus scrofa)
        
        TRIM33 monoubiquitinates SMAD4 (Sus scrofa)
        
        p-2S-SMAD2,3 [nucleoplasm] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by TGFB family members (Sus scrofa)
  - Signaling by TGF-beta Receptor Complex (Sus scrofa)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Sus scrofa)
      - Downregulation of SMAD2/3:SMAD4 transcriptional activity (Sus scrofa)
        
        TRIM33 monoubiquitinates SMAD4 (Sus scrofa)
        
        p-2S-SMAD2,3 [nucleoplasm] (Sus scrofa)

Participants

members

Participates

as an output of

TRIM33 monoubiquitinates SMAD4 (Sus scrofa)

Inferred From

p-2S-SMAD2,3 [nucleoplasm] (Homo sapiens)

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