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CUL5 [cytosol]
Stable Identifier
R-SSC-180528
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
CUL5, A0A5G2R2M6
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Class I MHC mediated antigen processing & presentation (Sus scrofa)
Antigen processing: Ubiquitination & Proteasome degradation (Sus scrofa)
Interaction of E3 with substrate and E2-Ub complex (Sus scrofa)
Ag-substrate:E3:E2:Ub [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
Polyubiquitination of substrate (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
E3:K48-polyubiquitinated substrate [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
E3:Ub:substrate [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
Release of E3 from polyubiquitinated substrate (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
E3:K48-polyubiquitinated substrate [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
Transfer of Ub from E2 to substrate and release of E2 (Sus scrofa)
Ag-substrate:E3:E2:Ub [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
E3:Ub:substrate [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Neddylation (Sus scrofa)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Sus scrofa)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Sus scrofa)
CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Sus scrofa)
CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by ERBB2 (Sus scrofa)
Downregulation of ERBB2 signaling (Sus scrofa)
CUL5 mediates ubiquitination of ERBB2 (Sus scrofa)
CUL5 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A5G2R2M6
Gene Names
CUL5
Reference Genes
ENSEMBL:ENSSSCG00000029198.4
Other Identifiers
100525708
GO:0005694
GO:0006511
GO:0016567
GO:0030163
GO:0031461
GO:0031466
GO:0031625
GO:0036211
GO:0043226
GO:0090734
Ssc.4549.1.A1_at
Ssc.8607.1.S1_at
Participates
as a component of
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 [endocytic vesicle membrane] (Sus scrofa)
CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Sus scrofa)
Cul5-SCF complex [cytosol] (Sus scrofa)
Other forms of this molecule
CUL5 [cytosol]
Inferred From
CUL5 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000166266
Ensembl
ENSSSCT00000078414
,
ENSSSCP00000068452
,
ENSSSCG00000029198
VGNC
87089
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