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active PDGF-BB dimer [extracellular region]
Stable Identifier
R-SSC-184206
Type
Complex
Species
Sus scrofa
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Hemostasis (Sus scrofa)
Platelet activation, signaling and aggregation (Sus scrofa)
Response to elevated platelet cytosolic Ca2+ (Sus scrofa)
Platelet degranulation (Sus scrofa)
Exocytosis of platelet alpha granule contents (Sus scrofa)
Platelet alpha granule contents [extracellular region] (Sus scrofa)
PDGF dimer [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Signal Transduction (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
PIP3 activates AKT signaling (Sus scrofa)
Negative regulation of the PI3K/AKT network (Sus scrofa)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Sus scrofa)
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
Activator:PI3K [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
Activator:PI3K [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
RAS GEFs promote RAS nucleotide exchange (Sus scrofa)
RAS GEFs [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by PDGF (Sus scrofa)
Autophosphorylation of PDGF alpha receptors (Sus scrofa)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Sus scrofa)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Phospho PDGF alpha receptor:PDGF dimers [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Autophosphorylation of PDGF alpha/beta receptors (Sus scrofa)
PDGF alpha/beta:PDGF AB and BB dimers [plasma membrane] (Sus scrofa)
PDGF AB or BB homodimers [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Phospho PDGF alpha-beta dimer:PDGF AB or BB dimers [plasma membrane] (Sus scrofa)
PDGF AB or BB homodimers [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Autophosphorylation of PDGF beta receptors (Sus scrofa)
PDGF beta receptor:PDGF chain B homodimer [plasma membrane] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Phospho PDGF beta receptor: PDGF chain B homodimer [plasma membrane] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Downstream signal transduction (Sus scrofa)
Activated PLC gamma dissociates from the PDGF receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Activation of Src (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Crk binds to the active PDGF receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
GAP binds to PDGF-beta receptors only (Sus scrofa)
Phospho PDGF beta receptor: PDGF chain B homodimer [plasma membrane] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Phospho-beta receptor homodimer:GAP [plasma membrane] (Sus scrofa)
Phospho PDGF beta receptor: PDGF chain B homodimer [plasma membrane] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
GRB2:SOS1 complex binds to the active receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Grb7 binds to the active PDGF receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Nck binds to the active PDGF receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PI3-kinase binds to the active receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PLC-gamma binds to the active receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Phosphorylation of PLCgamma by PDGFR (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
SH2 domain of Src binds to the active receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
SHP2 binds to the active receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:SHP2 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
STAT binds to the active receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
p130Cas and C3G bind PDGFR bound Crk (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF dimer binds two receptors simultaneously (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF:PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGF-BB clevage by Furin (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGFRs bind type I TKI (Sus scrofa)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Sus scrofa)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
PTPN12 dephosphorylates PDGFRB at Y1021 (Sus scrofa)
p-PDGFRB homo and heterodimers [plasma membrane] (Sus scrofa)
Phospho PDGF alpha-beta dimer:PDGF AB or BB dimers [plasma membrane] (Sus scrofa)
PDGF AB or BB homodimers [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Phospho PDGF beta receptor: PDGF chain B homodimer [plasma membrane] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
p-PDGFRB homo and heterodimers dephosphorylated at Y1021 [plasma membrane] (Sus scrofa)
Phospho PDGF alpha-beta dimer:PDGF AB or BB dimers dephosphorylated at Y1021 of PDGFRB [plasma membrane] (Sus scrofa)
PDGF AB or BB homodimers [extracellular region] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
Phospho PDGF beta receptor: PDGF chain B homodimer dephosphorylated at Y1021 [plasma membrane] (Sus scrofa)
active PDGF-BB dimer [extracellular region] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
PDGFB [extracellular region]
(Sus scrofa)
Participates
as a member of
PDGF dimer [extracellular region] (Sus scrofa)
PDGF AB or BB homodimers [extracellular region] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
as a component of
Phospho PDGF beta receptor: PDGF chain B homodimer dephosphorylated at Y1021 [plasma membrane] (Sus scrofa)
Phospho PDGF beta receptor: PDGF chain B homodimer [plasma membrane] (Sus scrofa)
PDGF beta receptor:PDGF chain B homodimer [plasma membrane] (Sus scrofa)
as an output of
PDGF-BB clevage by Furin (Sus scrofa)
Inferred From
active PDGF-BB dimer [extracellular region]
(Homo sapiens)
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