Reactome | Homologues of HSP90AA1 [cytosol]

Cell Cycle (Sus scrofa)

- Cell Cycle, Mitotic (Sus scrofa)
  - M Phase (Sus scrofa)
    - Mitotic Prometaphase (Sus scrofa)
      - Recruitment of NuMA to mitotic centrosomes (Sus scrofa)
        
        Association of NuMA with microtubules (Sus scrofa)
        
        Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Sus scrofa)
        
        Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Sus scrofa)
        
        Mature centrosome:nucleated microtubules [cytosol] (Sus scrofa)
        
        Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Translocation of NuMA to the centrosomes (Sus scrofa)
        
        Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Sus scrofa)
        
        Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
  - Mitotic G2-G2/M phases (Sus scrofa)
    - G2/M Transition (Sus scrofa)
      - AURKA Activation by TPX2 (Sus scrofa)
        
        TPX2 binds AURKA at centrosomes (Sus scrofa)
        
        Centrosome:AURKA [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Centrosome:AURKA:TPX2:HMMR [cytosol] (Sus scrofa)
        
        Centrosome:AURKA [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        TPX2 promotes AURKA autophosphorylation (Sus scrofa)
        
        Centrosome:AURKA:TPX2:HMMR [cytosol] (Sus scrofa)
        
        Centrosome:AURKA [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Centrosome:p-T288-AURKA:TPX2:HMMR [cytosol] (Sus scrofa)
        
        Centrosome:p-T288-AURKA [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - Centrosome maturation (Sus scrofa)
        
        Loss of proteins required for interphase microtubule organization from the centrosome (Sus scrofa)
        
        Loss of C-Nap-1 from centrosomes (Sus scrofa)
        
        cNAP-1 depleted centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Loss of Nlp from mitotic centrosomes (Sus scrofa)
        
        Dissociation of Phospho-Nlp from the centrosome (Sus scrofa)
        
        Nlp-depleted centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        centrosome containing phosphorylated Nlp [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Plk1-mediated phosphorylation of Nlp (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        centrosome containing phosphorylated Nlp [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Recruitment of mitotic centrosome proteins and complexes (Sus scrofa)
        
        Recruitment of CDK11p58 to the centrosomes (Sus scrofa)
        
        Centrosomes containing recruited CDK11p58 [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Recruitment of Plk1 to centrosomes (Sus scrofa)
        
        Centrosome associated Plk1 [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Sus scrofa)
        
        Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - Regulation of PLK1 Activity at G2/M Transition (Sus scrofa)
        
        AJUBA binds centrosome-associated AURKA (Sus scrofa)
        
        Centrosome:AURKA [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Centrosome:AURKA:AJUBA [cytosol] (Sus scrofa)
        
        Centrosome:AURKA [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        AJUBA facilitates AURKA autophosphorylation (Sus scrofa)
        
        Centrosome:AURKA:AJUBA [cytosol] (Sus scrofa)
        
        Centrosome:AURKA [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Centrosome:p-T288-AURKA [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        AURKA phosphorylates PLK1 (Sus scrofa)
        
        Centrosome:p-T288-AURKA [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Sus scrofa)
        
        Centrosome:p-T288-AURKA [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        BORA binds PLK1 and AURKA (Sus scrofa)
        
        Centrosome:p-T288-AURKA [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Sus scrofa)
        
        Centrosome:p-T288-AURKA [cytosol] (Sus scrofa)
        
        centrosome [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - The role of GTSE1 in G2/M progression after G2 checkpoint (Sus scrofa)
        
        GTSE1 binds CDKN1A (Sus scrofa)
        
        GTSE1:CDKN1A:FKBPL:HSP90 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)

Cellular responses to stimuli (Sus scrofa)

- Cellular responses to stress (Sus scrofa)
  - Cellular response to heat stress (Sus scrofa)
    - HSF1 activation (Sus scrofa)
      - Dissociation of cytosolic HSF1:HSP90 complex (Sus scrofa)
        
        HSF1:HSP90:PTGES3 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Sus scrofa)
        
        HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
  - HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Sus scrofa)
    - AR binds AR agonists (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:AR [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:AR:AR agonists [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - AR binds AR antagonists (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:AR [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:AR:AR antagonists [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - ATP binding to HSP90 triggers conformation change (Sus scrofa)
      - HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90 dimer:ATP:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - Androgens binds AR (in the HSP90 chaperone complex) (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:AR [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Sus scrofa)
      - HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90 dimer:ATP:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90 dimer:ATP:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:nascent protein: [cytosol] (Sus scrofa)
        
        HSP90 dimer:ATP:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP5:PTGES3:nascent protein: [cytosol] (Sus scrofa)
        
        HSP90 dimer:ATP:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Sus scrofa)
      - HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90 dimer:ATP:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90 dimer:ATP:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligands [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:PGR:P4 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - NR3C1 binds NR3C1 agonists (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:NR3C1 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 agonists [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:NR3C1 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 agonists [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligands [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - NR3C2 binds NR3C2 antagonists (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - NR3C2:NR3C2 antagonists [cytosol] (Sus scrofa)
        
        HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - NR3C2 binds fludrocortisone (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - NR3C2:fludrocortisone [cytosol] (Sus scrofa)
        
        HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - P4 bind PGR (in the HSP90 chaperone complex) (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:PGR:P4 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - PGR binds PGR agonists (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - PGR:PGR agonists [cytosol] (Sus scrofa)
        
        HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - PGR binds PGR antagonists (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - PGR:PGR antagonists [cytosol] (Sus scrofa)
        
        HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Sus scrofa)
      - HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Sus scrofa)
      - HSP90:ATP:FKBP4:PTGES3:nascent protein: [cytosol] (Sus scrofa)
        
        HSP90 dimer:ATP:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90 dimer:ATP:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Sus scrofa)
      - HSP90:ATP:FKBP5:PTGES3:nascent protein: [cytosol] (Sus scrofa)
        
        HSP90 dimer:ATP:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
        
        HSP90 dimer:ATP:nascent protein [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)

Developmental Biology (Sus scrofa)

- Nervous system development (Sus scrofa)
  - Axon guidance (Sus scrofa)
    - Semaphorin interactions (Sus scrofa)
      - Sema3A PAK dependent Axon repulsion (Sus scrofa)
        
        Dimerization of LIMK1 by Hsp90 (Sus scrofa)
        
        HSP90AA1,HSP90AB1 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        pLIMK dimer:HSP-90 [cytosol] (Sus scrofa)
        
        HSP90AA1,HSP90AB1 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Transphosphorylation of pLIMK1 (Sus scrofa)
        
        HSP90AA1,HSP90AB1 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        pLIMK dimer:HSP-90 [cytosol] (Sus scrofa)
        
        HSP90AA1,HSP90AB1 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)

Immune System (Sus scrofa)

- Innate Immune System (Sus scrofa)
  - DDX58/IFIH1-mediated induction of interferon-alpha/beta (Sus scrofa)
    - HSP90 binds TBK1 and IRF3 (Sus scrofa)
      - HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90:TBK1:IRF3 [cytosol] (Sus scrofa)
        
        HSP90:HSP90 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Sus scrofa)
    - Regulation of actin dynamics for phagocytic cup formation (Sus scrofa)
      - Dimerization of LIMK1 by Hsp90 (Sus scrofa)
        
        HSP90AA1,HSP90AB1 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        pLIMK dimer:HSP-90 [cytosol] (Sus scrofa)
        
        HSP90AA1,HSP90AB1 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - Transphosphorylation of pLIMK1 (Sus scrofa)
        
        HSP90AA1,HSP90AB1 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        pLIMK dimer:HSP-90 [cytosol] (Sus scrofa)
        
        HSP90AA1,HSP90AB1 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)

Metabolism (Sus scrofa)

- Metabolism of nitric oxide: NOS3 activation and regulation (Sus scrofa)
  - eNOS activation (Sus scrofa)
    - AKT1 phosphorylates eNOS (Sus scrofa)
      - p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - BH2 binding can lead to eNOS uncoupling (Sus scrofa)
      - p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - HSP90 binds eNOS:Caveolin-1:CaM complex (Sus scrofa)
      - Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Sus scrofa)
      - p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - Uncoupled eNOS favours the formation of superoxide (Sus scrofa)
      - p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - eNOS synthesizes NO (Sus scrofa)
      - p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
- Metabolism of vitamins and cofactors (Sus scrofa)
  - Metabolism of cofactors (Sus scrofa)
    - Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Sus scrofa)
      - BH2 binding can lead to eNOS uncoupling (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)

Organelle biogenesis and maintenance (Sus scrofa)

- Cilium Assembly (Sus scrofa)
  - Anchoring of the basal body to the plasma membrane (Sus scrofa)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - C2CD3 binds the mother centriole (Sus scrofa)
      - mother centriole [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Sus scrofa)
      - basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Sus scrofa)
        
        basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - MARK4 binds ODF2 in the centriole (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Sus scrofa)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Sus scrofa)
        
        basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - Recruitment of transition zone proteins (Sus scrofa)
      - basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - The distal appendage proteins recruit TTBK2 (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)

Programmed Cell Death (Sus scrofa)

- Regulated Necrosis (Sus scrofa)
  - RIPK1-mediated regulated necrosis (Sus scrofa)
    - Regulation of necroptotic cell death (Sus scrofa)
      - MLKL binds HSP90:CDC37 (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        MLKL:HSP90:CDC37 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - RIPK3 binds HSP90:CDC37 (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        RIPK3:HSP90:CDC37 [cytosol] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by Nuclear Receptors (Sus scrofa)
  - ESR-mediated signaling (Sus scrofa)
    - Extra-nuclear estrogen signaling (Sus scrofa)
      - eNOS synthesizes NO (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
- Signaling by Receptor Tyrosine Kinases (Sus scrofa)
  - Signaling by ERBB2 (Sus scrofa)
    - Downregulation of ERBB2 signaling (Sus scrofa)
      - CHIP (STUB1) mediates ubiquitination of ERBB2 (Sus scrofa)
        
        ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - CUL5 mediates ubiquitination of ERBB2 (Sus scrofa)
        
        ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - Drug-mediated inhibition of ERBB2 signaling (Sus scrofa)
      - ERBB2 binds TKIs (Sus scrofa)
        
        ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
    - Trans-autophosphorylation of ERBB2 heterodimers (Sus scrofa)
      - ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Sus scrofa)
        
        HSP90 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
  - Signaling by VEGF (Sus scrofa)
    - VEGFA-VEGFR2 Pathway (Sus scrofa)
      - Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - CRK binds BCAR1 and or PXN (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1/p-Y31,Y118-PAX:CRK [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - DOCK180:ELMO binds CRK (Sus scrofa)
        
        CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1/p-Y31,Y118-PAX:CRK [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Sus scrofa)
        
        CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - HSP90AA1 binds p-6Y-VEGFR2 (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - PXN binds p-6Y,S732-PTK2 (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:PXN [plasma membrane] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - VEGFR2 mediated vascular permeability (Sus scrofa)
        
        AKT1 phosphorylates eNOS (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        HSP90 binds eNOS:Caveolin-1:CaM complex (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        eNOS synthesizes NO (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
        
        p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
      - p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
        
        VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)
- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
  - Signaling by Rho GTPases (Sus scrofa)
    - RHO GTPase cycle (Sus scrofa)
      - RHOBTB GTPase Cycle (Sus scrofa)
        
        RHOBTB2 GTPase cycle (Sus scrofa)
        
        RHOBTB2 binds GTP (Sus scrofa)
        
        HSP90:CDC37 [cytosol] (Sus scrofa)
        
        HSP90 dimer [cytosol] (Sus scrofa)
        
        HSP90AA1,HSP90AB1 [cytosol] (Sus scrofa)
        
        Homologues of HSP90AA1 [cytosol] (Sus scrofa)