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EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane]
Stable Identifier
R-SSC-1963593
Type
Complex
Species
Sus scrofa
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
PIP3 activates AKT signaling (Sus scrofa)
Negative regulation of the PI3K/AKT network (Sus scrofa)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Sus scrofa)
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
Activator:PI3K [plasma membrane] (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
Activator:PI3K [plasma membrane] (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
RAS GEFs promote RAS nucleotide exchange (Sus scrofa)
RAS GEFs [plasma membrane] (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:SOS1 [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
GRB2:SOS1:p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
Signaling by Non-Receptor Tyrosine Kinases (Sus scrofa)
Signaling by PTK6 (Sus scrofa)
ERBB2 Activates PTK6 Signaling (Sus scrofa)
Activated ERBB2 binds PTK6 (BRK) (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
ERBB2 promotes PTK6 autophosphorylation (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by ERBB2 (Sus scrofa)
Downregulation of ERBB2 signaling (Sus scrofa)
MATK (CSK homologous kinase) binds phosphorylated ERBB2 (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers:MATK [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
PTPN18 binds ERBB2:EGFR heterodimers (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers:PTPN18 [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers:PTPN18 [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
ERBB2 Activates PTK6 Signaling (Sus scrofa)
Activated ERBB2 binds PTK6 (BRK) (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
ERBB2 promotes PTK6 autophosphorylation (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
ERBB2 Regulates Cell Motility (Sus scrofa)
MEMO1 binds RHOA:GTP:DIAPH1 (Sus scrofa)
p-ERBB2 heterodimers:MEMO1 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers:MEMO1:RHOA:GTP:DIAPH1 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers:MEMO1 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2 heterodimers bind MEMO1 (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers:MEMO1 [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
PI3K events in ERBB2 signaling (Sus scrofa)
Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Sus scrofa)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
SHC1 events in ERBB2 signaling (Sus scrofa)
SHC1 phosphorylation by ERBB2 heterodimers (Sus scrofa)
SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
Trans-autophosphorylation of ERBB2 heterodimers (Sus scrofa)
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
EGF:p-6Y-EGFR [plasma membrane]
(Sus scrofa)
phospho-p-6Y,Y1112-ERBB2 [plasma membrane]
(Sus scrofa)
Participates
as a member of
p-6Y-ERBB2 heterodimers [plasma membrane] (Sus scrofa)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Sus scrofa)
Inferred From
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane]
(Homo sapiens)
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