Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
RPS6KA5 [nucleoplasm]
Stable Identifier
R-SSC-198657
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
I3LQZ5
Locations in the PathwayBrowser
Expand all
Developmental Biology (Sus scrofa)
Nervous system development (Sus scrofa)
Axon guidance (Sus scrofa)
NCAM signaling for neurite out-growth (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-17 signaling (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
ERK/MAPK targets (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
p38MAPK phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
Innate Immune System (Sus scrofa)
C-type lectin receptors (CLRs) (Sus scrofa)
CD209 (DC-SIGN) signaling (Sus scrofa)
Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit (Sus scrofa)
RPS6KA5(MSK1/SAPK1):PKA catalytic subunits [nucleoplasm] (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
ERK/MAPK targets (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
p38MAPK phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
ERK/MAPK targets (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
p38MAPK phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
ERK/MAPK targets (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
p38MAPK phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
ERK/MAPK targets (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
p38MAPK phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
ERK/MAPK targets (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
p38MAPK phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
ERK/MAPK targets (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
p38MAPK phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
ERK/MAPK targets (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
p38MAPK phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
ERK/MAPK targets (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
p38MAPK phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
ERK/MAPK targets (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
p38MAPK phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by NTRKs (Sus scrofa)
Signaling by NTRK1 (TRKA) (Sus scrofa)
Nuclear Events (kinase and transcription factor activation) (Sus scrofa)
ERK/MAPK targets (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
p38MAPK phosphorylates MSK1 (Sus scrofa)
RPS6KA5 [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:I3LQZ5
Reference Genes
BioGPS Gene:100623751
ENSEMBL:ENSSSCG00000024377.4
Monarch:100623751
NCBI Gene:100623751
UCSC:I3LQZ5
Reference Transcript
RefSeq:XM_021099611.1
Other Identifiers
GO:0000166
GO:0000287
GO:0003824
GO:0004672
GO:0004674
GO:0004713
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0006325
GO:0006338
GO:0006355
GO:0006468
GO:0016301
GO:0016740
GO:0035175
GO:0035556
GO:0038202
GO:0043687
GO:0044022
GO:0044024
GO:0045892
GO:0045944
GO:0070498
GO:0099175
GO:0106310
GO:0140096
Ssc.2132.1.S1_a_at
Participates
as a member of
RPS6KA5(MSK1/SAPK1):PKA catalytic subunits [nucleoplasm] (Sus scrofa)
as an input of
p38MAPK phosphorylates MSK1 (Sus scrofa)
ERK1/2 phosphorylates MSK1 (Sus scrofa)
Other forms of this molecule
phospho-p-S212,S360,S376,T581-RPS6KA5 [nucleoplasm]
Inferred From
RPS6KA5 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_020955270.1
ENSEMBL
ENSSSCT00000026351
,
ENSSSCG00000024377
,
ENSSSCP00000026527
VGNC
92444
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text