Reactome | ATF1 [nucleoplasm]

ATF1 [nucleoplasm]

Stable Identifier

R-SSC-199900

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

ATF1, F1SHC5

Locations in the PathwayBrowser

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Immune System (Sus scrofa)

- Cytokine Signaling in Immune system (Sus scrofa)
  - Signaling by Interleukins (Sus scrofa)
    - Interleukin-17 signaling (Sus scrofa)
      - MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        CREB phosphorylation (Sus scrofa)
        
        MSK1 activates ATF1 (Sus scrofa)
        
        ATF1 [nucleoplasm] (Sus scrofa)
- Innate Immune System (Sus scrofa)
  - Toll-like Receptor Cascades (Sus scrofa)
    - Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
      - MyD88 cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        CREB phosphorylation (Sus scrofa)
        
        MSK1 activates ATF1 (Sus scrofa)
        
        ATF1 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
      - Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        CREB phosphorylation (Sus scrofa)
        
        MSK1 activates ATF1 (Sus scrofa)
        
        ATF1 [nucleoplasm] (Sus scrofa)
      - Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        CREB phosphorylation (Sus scrofa)
        
        MSK1 activates ATF1 (Sus scrofa)
        
        ATF1 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
      - MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        CREB phosphorylation (Sus scrofa)
        
        MSK1 activates ATF1 (Sus scrofa)
        
        ATF1 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
      - MyD88-independent TLR4 cascade (Sus scrofa)
        
        TRIF(TICAM1)-mediated TLR4 signaling (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        CREB phosphorylation (Sus scrofa)
        
        MSK1 activates ATF1 (Sus scrofa)
        
        ATF1 [nucleoplasm] (Sus scrofa)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        CREB phosphorylation (Sus scrofa)
        
        MSK1 activates ATF1 (Sus scrofa)
        
        ATF1 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
      - MyD88 cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        CREB phosphorylation (Sus scrofa)
        
        MSK1 activates ATF1 (Sus scrofa)
        
        ATF1 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
      - MyD88 dependent cascade initiated on endosome (Sus scrofa)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        CREB phosphorylation (Sus scrofa)
        
        MSK1 activates ATF1 (Sus scrofa)
        
        ATF1 [nucleoplasm] (Sus scrofa)
    - Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
      - MyD88 dependent cascade initiated on endosome (Sus scrofa)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Sus scrofa)
        
        CREB phosphorylation (Sus scrofa)
        
        MSK1 activates ATF1 (Sus scrofa)
        
        ATF1 [nucleoplasm] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by Receptor Tyrosine Kinases (Sus scrofa)
  - Signaling by NTRKs (Sus scrofa)
    - Signaling by NTRK1 (TRKA) (Sus scrofa)
      - Nuclear Events (kinase and transcription factor activation) (Sus scrofa)
        
        CREB phosphorylation (Sus scrofa)
        
        MSK1 activates ATF1 (Sus scrofa)
        
        ATF1 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SHC5

Gene Names

ATF1

Reference Genes

ENSEMBL:ENSSSCG00000016138

Other Identifiers

102158891

GO:0000977

GO:0000978

GO:0000981

GO:0001228

GO:0003674

GO:0003677

GO:0003700

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005667

GO:0006355

GO:0006357

GO:0007165

GO:0008150

GO:0009058

GO:0010035

GO:0014074

GO:0019933

GO:0032991

GO:0034641

GO:0042802

GO:0043226

GO:0043565

GO:0045944

GO:0046982

GO:0090575

GO:1990589

GO:1990590

Participates

as an input of

MSK1 activates ATF1 (Sus scrofa)

Other forms of this molecule

phospho-ATF1 [nucleoplasm]

Inferred From

ATF1 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000123268

Ensembl

ENSSSCG00000016138, ENSSSCT00000017571, ENSSSCP00000017098

VGNC

85605

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