Reactome | DSG3 [plasma membrane]

DSG3 [plasma membrane]

Stable Identifier

R-SSC-201590

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

DSG3, I3LU54

Locations in the PathwayBrowser

Expand all

Developmental Biology (Sus scrofa)

- Keratinization (Sus scrofa)
  - Formation of the cornified envelope (Sus scrofa)
    - Fillagrin and keratin intermediate filaments polymerize forming a network (Sus scrofa)
      - FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG3 [plasma membrane] (Sus scrofa)
      - FLG-Keratin filament network [plasma membrane] (Sus scrofa)
        
        FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG3 [plasma membrane] (Sus scrofa)
    - PERP binds desmosomes (Sus scrofa)
      - Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG3 [plasma membrane] (Sus scrofa)
      - Desmosome:PERP [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG3 [plasma membrane] (Sus scrofa)
    - Plasma membrane resorption (Sus scrofa)
      - Mature cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-cornified envelope:CDSN [plasma membrane] (Sus scrofa)
        
        No FGN-Cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-late cornified envelope [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome network [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG3 [plasma membrane] (Sus scrofa)
  - Keratin filaments bind cell-cell adhesion complexes (Sus scrofa)
    - Desmosome [plasma membrane] (Sus scrofa)
      - Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG3 [plasma membrane] (Sus scrofa)
    - Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
      - Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG3 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:I3LU54

Gene Names

DSG3

Reference Genes

ENSEMBL:ENSSSCG00000027160.4

Other Identifiers

100625733

GO:0005509

GO:0005886

GO:0007155

GO:0007156

GO:0016020

GO:0030057

GO:0070161

GO:0098609

Participates

as a member of

Desmogelins [plasma membrane] (Sus scrofa)

as an input of

Caspase-mediated cleavage of Desmoglein 3 (Sus scrofa)

Other forms of this molecule

DSG3 [cornified envelope]

DSG3 [cytosol]

DSG3 [plasma membrane]

Inferred From

DSG3 [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000134757

Ensembl

ENSSSCT00000027548, ENSSSCG00000027160, ENSSSCP00000027653

VGNC

87457