Reactome | COL4A4 [endoplasmic reticulum lumen]

COL4A4 [endoplasmic reticulum lumen]

Stable Identifier

R-SSC-2023640

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

endoplasmic reticulum lumen

Synonyms

3x4Hyp-3Hyp-GlcGalHyl-COL4A4, A0A287AZF2

Locations in the PathwayBrowser

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Extracellular matrix organization (Sus scrofa)

- Collagen formation (Sus scrofa)
  - Collagen biosynthesis and modifying enzymes (Sus scrofa)
    - Glucosylation of collagen propeptide hydroxylysines (Sus scrofa)
      - PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum membrane] (Sus scrofa)
        
        Glucosyl-galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Sus scrofa)
        
        3,4-Hyp Glu-Gal-Hyl-collagen propeptides [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL4A4 [endoplasmic reticulum lumen] (Sus scrofa)
    - PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Sus scrofa)
      - Glucosyl-galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Sus scrofa)
        
        3,4-Hyp Glu-Gal-Hyl-collagen propeptides [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL4A4 [endoplasmic reticulum lumen] (Sus scrofa)
      - PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum membrane] (Sus scrofa)
        
        Glucosyl-galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Sus scrofa)
        
        3,4-Hyp Glu-Gal-Hyl-collagen propeptides [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL4A4 [endoplasmic reticulum lumen] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287AZF2

Gene Names

COL4A4

Reference Genes

ENSEMBL:ENSSSCG00000016244

ENSEMBL:ENSSSCG00000016244.5 COL4A4

Participates

as a candidate of

3,4-Hyp Glu-Gal-Hyl-collagen propeptides [endoplasmic reticulum lumen] (Sus scrofa)

Other forms of this molecule

COL4A4 [endoplasmic reticulum lumen]

COL4A4 [extracellular region]

Inferred From

3x4Hyp-3Hyp-GlcGalHyl-COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)

Modified Residues

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,3S)-3-hydroxyproline at unknown position

PsiMod Name

(2S,3S)-3-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.

Name

O5-glucosylgalactosyl-L-hydroxylysine at unknown position

PsiMod Name

O5-glucosylgalactosyl-L-hydroxylysine

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to O5-glucosylgalactosyl-L-hydroxylysine.

Cross References

OpenTargets

ENSG00000081052

VGNC

95980