Reactome | mature NGF homodimer:p75NTR [plasma membrane]

mature NGF homodimer:p75NTR [plasma membrane]

Stable Identifier

R-SSC-205123

Type

Complex

Species

Sus scrofa

Compartment

plasma membrane

Locations in the PathwayBrowser

Expand all

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

mature beta-NGF homodimer [extracellular region] (Sus scrofa)
NGFR [plasma membrane] (Sus scrofa)

Participates

as an input of

p75NTR binds to NADE (Sus scrofa)
p75NTR interacts with RIP2 (Sus scrofa)

as a component of

NGF:p75NTR:NADE [plasma membrane] (Sus scrofa)
NGF ligand:p75NTR:NRIF [plasma membrane] (Sus scrofa)
NGF:p75NTR:RIP2 [plasma membrane] (Sus scrofa)
NGF ligand:p75NTR:Phospho-IRAK1:polyubiquitinated TRAF6:p62 [plasma membrane] (Sus scrofa)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Sus scrofa)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Sus scrofa)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:Phospho-IKK-beta [plasma membrane] (Sus scrofa)

as an output of

NGF homodimer binds to p75NTR (Sus scrofa)

Inferred From

mature NGF homodimer:p75NTR [plasma membrane] (Homo sapiens)