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YWHAZ [cytosol]
Stable Identifier
R-SSC-206099
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
YWHAZ, F2Z558
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle Checkpoints (Sus scrofa)
G2/M Checkpoints (Sus scrofa)
G2/M DNA damage checkpoint (Sus scrofa)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Sus scrofa)
Association of p-S216-CDC25C with 14-3-3 proteins (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
FOXO-mediated transcription (Sus scrofa)
Regulation of localization of FOXO transcription factors (Sus scrofa)
14-3-3 proteins bind AKT-phosphorylated FOXO1 (Sus scrofa)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
p-T24,S256,S319-FOXO1:YWHAZ,YWHAQ,YWHAG,YWHAB [cytosol] (Sus scrofa)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
14-3-3 proteins bind AKT-phosphorylated FOXO3 (Sus scrofa)
YWHAZ dimer,YWHAQ dimer,SFN dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
p-T32,S253,S315-FOXO3:YWHAZ,YWHAQ,SFN [cytosol] (Sus scrofa)
YWHAZ dimer,YWHAQ dimer,SFN dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
14-3-3 proteins bind AKT-phosphorylated FOXO4 (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
p-T32,S197,S262-FOXO4:YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
TP53 Regulates Metabolic Genes (Sus scrofa)
DDIT4 binds 14-3-3 dimer (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
DDIT4:14-3-3 dimer [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
DDIT4:14-3-3 dimer [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
p-S939,T1462-TSC2:14-3-3 dimer [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
Hemostasis (Sus scrofa)
Platelet activation, signaling and aggregation (Sus scrofa)
GP1b-IX-V activation signalling (Sus scrofa)
GP1b-IX-V binds 14-3-3-zeta (Sus scrofa)
GPIb-IX-V:Collagen type I fibril:vWF:14-3-3-zeta [plasma membrane] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K (Sus scrofa)
GPIb-IX-V:Collagen type I fibril:vWF:14-3-3-zeta [plasma membrane] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
GPIb-IX-V:vWF:14-3-3-zeta:p85 [plasma membrane] (Sus scrofa)
GPIb-IX-V:Collagen type I fibril:vWF:14-3-3-zeta [plasma membrane] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress (Sus scrofa)
GPIb-IX-V:Collagen type I fibril:vWF:14-3-3-zeta [plasma membrane] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Rap1 signalling (Sus scrofa)
14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Sus scrofa)
14-3-3 beta, zeta [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Sus scrofa)
14-3-3 beta, zeta [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
Rap1 signal termination by Rap1GAPs (Sus scrofa)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Sus scrofa)
14-3-3 beta, zeta [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Sus scrofa)
14-3-3 zeta binding allows recruitment of PI3K (Sus scrofa)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
p-S585-IL3RB binds 14-3-3 proteins (Sus scrofa)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
Programmed Cell Death (Sus scrofa)
Apoptosis (Sus scrofa)
Intrinsic Pathway for Apoptosis (Sus scrofa)
Activation of BH3-only proteins (Sus scrofa)
Activation of BAD and translocation to mitochondria (Sus scrofa)
Activation of BAD by calcineurin (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
Sequestration of BAD protein by 14-3-3 (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by NOTCH (Sus scrofa)
Signaling by NOTCH4 (Sus scrofa)
NOTCH4 Activation and Transmission of Signal to the Nucleus (Sus scrofa)
NICD4 traffics to the nucleus (Sus scrofa)
p-4S-NICD4:YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase Effectors (Sus scrofa)
RHO GTPases activate PKNs (Sus scrofa)
Association of p-S216-CDC25C with 14-3-3 proteins (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
Signaling by WNT (Sus scrofa)
TCF dependent signaling in response to WNT (Sus scrofa)
Deactivation of the beta-catenin transactivating complex (Sus scrofa)
YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Sus scrofa)
XPO1:YWHAZ:p-S20-CBY1:CTNNB1 [cytosol] (Sus scrofa)
YWHAZ [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:F2Z558
Gene Names
YWHAZ
Reference Genes
ENSEMBL:ENSSSCG00000006062.5
Other Identifiers
780440
GO:0000122
GO:0002376
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0007165
GO:0019901
GO:0023052
GO:0031625
GO:0034330
GO:0042149
GO:0042802
GO:0044325
GO:0045824
GO:0048856
GO:0050815
GO:0051683
GO:0070372
GO:0090128
GO:0090168
GO:0098542
GO:0098978
GO:0140297
GO:0140311
GO:0140313
GO:1900181
GO:1904262
Ssc.1296.1.S1_at
Ssc.17423.1.S1_at
Participates
as a member of
14-3-3 beta, zeta [cytosol] (Sus scrofa)
as an input of
p-S585-IL3RB binds 14-3-3 proteins (Sus scrofa)
as a component of
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Sus scrofa)
XPO1:YWHAZ:p-S20-CBY1:CTNNB1 [cytosol] (Sus scrofa)
YWHAZ dimer [cytosol] (Sus scrofa)
Other forms of this molecule
YWHAZ [nucleoplasm]
Inferred From
YWHAZ [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000164924
Ensembl
ENSSSCP00000006472
,
ENSSSCT00000006651
,
ENSSSCG00000006062
VGNC
95047
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