Reactome | BTRC:CUL1:RBX1:SKP1 [cytosol]

BTRC:CUL1:RBX1:SKP1 [cytosol]

Stable Identifier

R-SSC-206748

Type

Complex

Species

Sus scrofa

Compartment

cytosol

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

CUL1 [cytosol] (Sus scrofa)
Ghost homologue of BTRC [cytosol] (Sus scrofa)
RBX1 [cytosol] (Sus scrofa)
SKP1 [cytosol] (Sus scrofa)

Participates

as an output of

Prolactin receptor is internalized (Sus scrofa)
Degradation of ubiquitinated beta catenin by the proteasome (Sus scrofa)

as an input of

PRLR binds SCF beta-TrCP complex (Sus scrofa)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Sus scrofa)
SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Sus scrofa)

as a component of

RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Sus scrofa)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Sus scrofa)
BTRC:CUL1:RBX1:SKP1:NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Sus scrofa)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Sus scrofa)

Inferred From

BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)

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