Reactome | EED [nucleoplasm]

EED [nucleoplasm]

Stable Identifier

R-SSC-212278

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

EED, A0A287B4M4

Locations in the PathwayBrowser

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Signal Transduction (Sus scrofa)

- Intracellular signaling by second messengers (Sus scrofa)
  - PIP3 activates AKT signaling (Sus scrofa)
    - PTEN Regulation (Sus scrofa)
      - Regulation of PTEN gene transcription (Sus scrofa)
        
        MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Sus scrofa)
        
        MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm] (Sus scrofa)
        
        MECOM:(PRC1.4,PRC2 (EZH2) core) [nucleoplasm] (Sus scrofa)
        
        PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Sus scrofa)
        
        PRC2 (EZH2) Core [nucleoplasm] (Sus scrofa)
        
        EED [nucleoplasm] (Sus scrofa)
        
        PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Sus scrofa)
        
        PRC2 (EZH2) Core [nucleoplasm] (Sus scrofa)
        
        EED [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287B4M4

Gene Names

EED

Reference Genes

ENSEMBL:ENSSSCG00000014915.5

Other Identifiers

100521029

GO:0001222

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005829

GO:0006325

GO:0006338

GO:0008047

GO:0016740

GO:0035098

GO:0036211

GO:0042054

GO:0042802

GO:0043226

GO:0098772

GO:0140096

Ssc.20341.1.S1_at

Ssc.25263.1.S1_at

Participates

as an input of

Formation of PRC2-EZH2 complex (Sus scrofa)

as a component of

PRC2 (EZH2) Core [nucleoplasm] (Sus scrofa)

Inferred From

EED [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000074266

Ensembl

ENSSSCT00000044568, ENSSSCG00000014915, ENSSSCP00000051060

VGNC

87552

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