Reactome | NCKIPSD [cytosol]

NCKIPSD [cytosol]

Stable Identifier

R-SSC-2197671

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

NCKIPSD, A0A8W4FEM2

Locations in the PathwayBrowser

Expand all

Immune System (Sus scrofa)

- Innate Immune System (Sus scrofa)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Sus scrofa)
    - Regulation of actin dynamics for phagocytic cup formation (Sus scrofa)
      - (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Sus scrofa)
        
        Mother filament:branching complex [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Sus scrofa)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Sus scrofa)
        
        SH3 domain proteins [cytosol] (Sus scrofa)
        
        NCKIPSD [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Sus scrofa)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Sus scrofa)
        
        SH3 domain proteins [cytosol] (Sus scrofa)
        
        NCKIPSD [cytosol] (Sus scrofa)
      - Detachment of WASP/WAVE (Sus scrofa)
        
        Mother filament:branching complex [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Sus scrofa)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Sus scrofa)
        
        SH3 domain proteins [cytosol] (Sus scrofa)
        
        NCKIPSD [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Sus scrofa)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Sus scrofa)
        
        SH3 domain proteins [cytosol] (Sus scrofa)
        
        NCKIPSD [cytosol] (Sus scrofa)
      - WIP binds WASP,N-WASP, activating them (Sus scrofa)
        
        CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Sus scrofa)
        
        SH3 domain proteins [cytosol] (Sus scrofa)
        
        NCKIPSD [cytosol] (Sus scrofa)
        
        SH3 domain proteins [cytosol] (Sus scrofa)
        
        NCKIPSD [cytosol] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
  - Signaling by Rho GTPases (Sus scrofa)
    - RHO GTPase Effectors (Sus scrofa)
      - RHO GTPases Activate WASPs and WAVEs (Sus scrofa)
        
        (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Sus scrofa)
        
        Mother filament:branching complex [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Sus scrofa)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Sus scrofa)
        
        SH3 domain proteins [cytosol] (Sus scrofa)
        
        NCKIPSD [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Sus scrofa)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Sus scrofa)
        
        SH3 domain proteins [cytosol] (Sus scrofa)
        
        NCKIPSD [cytosol] (Sus scrofa)
        
        Detachment of WASP/WAVE (Sus scrofa)
        
        Mother filament:branching complex [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Sus scrofa)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Sus scrofa)
        
        SH3 domain proteins [cytosol] (Sus scrofa)
        
        NCKIPSD [cytosol] (Sus scrofa)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Sus scrofa)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Sus scrofa)
        
        SH3 domain proteins [cytosol] (Sus scrofa)
        
        NCKIPSD [cytosol] (Sus scrofa)
        
        WIP binds WASP,N-WASP, activating them (Sus scrofa)
        
        CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Sus scrofa)
        
        SH3 domain proteins [cytosol] (Sus scrofa)
        
        NCKIPSD [cytosol] (Sus scrofa)
        
        SH3 domain proteins [cytosol] (Sus scrofa)
        
        NCKIPSD [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A8W4FEM2

Gene Names

NCKIPSD

Reference Genes

ENSEMBL:ENSSSCG00000011364.5

UCSC:A0A8W4FEM2 NCKIPSD

Other Identifiers

100524278

GO:0005634

GO:0006897

GO:0008180

GO:0010976

GO:0016192

GO:0030154

GO:0043226

GO:0048856

GO:0071933

Participates

as a member of

SH3 domain proteins [cytosol] (Sus scrofa)

Inferred From

NCKIPSD [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSSSCP00000077761, ENSSSCG00000011364, ENSSSCT00000101610

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